未登录 To be, or not to be cleaved: Directed evolution of a canonical serine protease inhibitor against active and inactive protease pair identifies binding loop residue critical for prevention of proteolytic cleavage 存在与否被切割:针对活性与失活蛋白酶对的方向性进化研究,鉴定了经典的丝氨酸蛋白酶抑制剂中与预防蛋白水解切割相关的关键结合环残基 Koller, Zsombor; Nemeth, Balint Zoltan; Kiss, Bence; Nagy, Zoltan Attila; Schlosser, Gitta; Magyar, Csaba; Demcsak, Alexandra; Sahin-Toth, Miklos; Pal, Gabor 分享 收藏
Targeting the complement lectin pathway with a highly specific MASP-2 inhibitor protects against renal ischemia-reperfusion injury 靶向凝集素途径的MASP-2特异性抑制剂可保护肾脏缺血再灌注损伤 Bongoni, Anjan K.; Kiss, Bence; McRae, Jennifer L.; Salvaris, Evelyn J.; Fisicaro, Nella; Muntz, Fenella; Nemeth, Balint Zoltan; Nagy, Zoltan Attila; Kocsis, Andrea; Gal, Peter; Cowan, Peter J. 分享 收藏
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Complement inhibition can decrease the haemostatic response in a microvascular bleeding model at multiple levels Golomingi, Murielle; Kohler, Jessie; Lamers, Christina; Pouw, Richard B.; Ricklin, Daniel; Dobo, Jozsef; Gal, Peter; Pal, Gabor; Kiss, Bence; Dopler, Arthur; Schmidt, Christoph Q.; Hardy, Elaissa Trybus; Lam, Wilbur; Schroeder, Verena 分享 收藏
Independent Membrane Binding Properties of the Caspase Generated Fragments of the Beaded Filament Structural Protein 1 (BFSP1) Involves an Amphipathic Helix Jarrin, Miguel; Kalligeraki, Alexia A.; Uwineza, Alice; Cawood, Chris S.; Brown, Adrian P.; Ward, Edward N.; Le, Khoa; Freitag-Pohl, Stefanie; Pohl, Ehmke; Kiss, Bence; Tapodi, Antal; Quinlan, Roy A. 分享 收藏
Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation (vol 298, 101985, 2022) Nagy, Zoltan Attila; Heja, David; Bencze, Daniel; Kiss, Bence; Boros, Eszter; Szakacs, David; Fodor, Krisztian; Wilmanns, Matthias; Kocsis, Andrea; Dobo, Jozsef; Gal, Peter; Harmat, Veronika; Pal, Gabor 分享 收藏
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Complement lectin pathway components MBL and MASP-1 promote haemostasis upon vessel injury in a microvascular bleeding model Golomingi, Murielle; Kohler, Jessie; Jenny, Lorenz; Hardy, Elaissa T.; Dobo, Jozsef; Gal, Peter; Pal, Gabor; Kiss, Bence; Lam, Wilbur A.; Schroeder, Verena 分享 收藏
Competitive inhibition of the classical complement pathway using exogenous single-chain C1q recognition proteins Vadaszi, Henrietta; Kiss, Bence; Micsonai, Andras; Schlosser, Gitta; Szaniszlo, Tamas; Kovacs, Reka A.; Gyoerffy, Balazs A.; Kekesi, Katalin A.; Goto, Yuji; Uzonyi, Barbara; Liliom, Karoly; Kardos, Jozsef 分享 收藏
Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation Nagy, Zoltan Attila; Heja, David; Bencze, Daniel; Kiss, Bence; Boros, Eszter; Szakacs, David; Fodor, Krisztian; Wilmanns, Matthias; Kocsis, Andrea; Dobo, Jozsef; Gal, Peter; Harmat, Veronika; Pal, Gabor 分享 收藏
Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PL A2R1-associated membranous nephropathy Haddad, George; Lorenzen, Johan M.; Ma, Hong; Haan, Noortje de; Seeger, Harald; Zaghrini, Christelle; Brandt, Simone; Kolling, Malte; Wegmann, Urs; Kiss, Bence; Pal, Gabor; Gal, Peter; Wuthrich, Rudolf P.; Wuhrer, Manfred; Beck, Laurence H.; Salant, David J.; Lambeau, Gerard; Kistler, Andreas D. 分享 收藏
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MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked Dobo, Jozsef; Szakacs, David; Oroszlan, Gabor; Kortvely, Elod; Kiss, Bence; Boros, Eszter; Szasz, Robert; Zavodszky, Peter; Gal, Peter; Pal, Gabor 分享 收藏
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