未登录

S

Siyue Lou

Zhejiang Chinese Medical University

H指数:12

被引数:474

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Selective PI3Kδ inhibitor TYM-3-98 suppresses AKT/mTOR/SREBP1-mediated lipogenesis and promotes ferroptosis in KRAS-mutant colorectal cancer

选择性PI3Kδ 抑制剂TYM-3-98抑制AKT/mTOR/SREBP1-mediated脂肪生成并促进KRAS突变型结直肠癌的铁死亡

CELL DEATH & DISEASE

IF9.6

2024-07-032

OAAI

TYM-3-98, a novel selective inhibitor of PI3Kδ, demonstrates promising preclinical antitumor activity in B-cell lymphomas

TYM-3-98是一种新型的PI3Kδ 选择性抑制剂，在b细胞淋巴瘤中表现出有希望的临床前抗肿瘤活性

IF5.1

2024-06-012

PRE

Discovery of Highly Selective and Orally Bioavailable PI3Kδ Inhibitors with Anti-Inflammatory Activity for Treatment of Acute Lung Injury

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-08-225

PRE

A novel sesquiterpene lactone fraction from Eupatorium chinense L. suppresses hepatocellular carcinoma growth by triggering ferritinophagy and mitochondrial damage

IF8.3

2023-04-0113

PRE

Hydnocarpin D attenuates lipopolysaccharide-induced acute lung injury via MAPK/NF-κB and Keap1/Nrf2/HO-1 pathway

IF8.3

2022-07-0145

PRE

Inhibition of retinoic acid receptor α phosphorylation represses the progression of triple-negative breast cancer via transactivating miR-3074-5p to target DHRS3

抑制维甲酸受体 α 磷酸化通过反式激活miR-3074-5p靶向DHRS3抑制三阴性乳腺癌的进展

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

IF12.8

2021-04-2612

OAAI

Jatamanvaltrate P induces cell cycle arrest, apoptosis and autophagy in human breast cancer cells in vitro and in vivo

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2017-05-0135

PREAI

Am80-GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia-associated infection andmortality

EMBO MOLECULAR MEDICINE

IF8.3

2016-10-1313

OAAI

DJ-1 as a human oncogene and potential therapeutic target

BIOCHEMICAL PHARMACOLOGY

IF5.6

2015-02-01106

PREAI

The Lost Intrinsic Fragmentation of MAT1 Protein During Granulopoiesis Promotes the Growth and Metastasis of Leukemic Myeloblasts

粒细胞生成过程中MAT1蛋白的内在片段化丢失促进白血病成髓细胞的生长和转移

IF3.6

2013-10-0413

OAAI

Efficacy of all-trans retinoid acid in preventing nickel induced cardiotoxicity in myocardial cells of rats

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2013-01-0113

PREAI