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Tyrosine Kinase Inhibitors. 20. Optimization of Substituted Quinazoline and Pyrido[3,4-d]pyrimidine Derivatives as Orally Active, Irreversible Inhibitors of the Epidermal Growth Factor Receptor Family Smaill, Jeff B.; Gonzales, Andrea J.; Spicer, Julie A.; Lee, Helen; Reed, Jessica E.; Sexton, Karen; Althaus, Irene W.; Zhu, Tong; Black, Shannon L.; Blaser, Adrian; Denny, William A.; Ellis, Paul A.; Fakhoury, Stephen; Harvey, Patricia J.; Hook, Ken; McCarthy, Florence O. J.; Palmer, Brian D.; Rivault, Freddy; Schlosser, Kevin; Ellis, Teresa; Thompson, Andrew M.; Trachet, Erin; Winters, R. Thomas; Tecle, Haile; Bridges, Alexander 分享 收藏
Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor Gonzales, Andrea J.; Hook, Kenneth E.; Althaus, Irene W.; Ellis, Paul A.; Trachet, Erin; Delaney, Amy M.; Harvey, Patricia J.; Ellis, Teresa A.; Amato, Danielle M.; Nelson, James M.; Fry, David W.; Zhu, Tong; Loi, Cho-Ming; Fakhoury, Stephen A.; Schlosser, Kevin M.; Sexton, Karen E.; Winters, R. Thomas; Reed, Jessica E.; Bridges, Alex J.; Lettiere, Daniel J.; Baker, Deborah A.; Yang, Jianxin; Lee, Helen T.; Tecle, Haile; Vincent, Patrick W. 分享 收藏
Tyrosine kinase inhibitors.: 19.: 6-alkynamides of 4-anilinoquinazolines and 4-anilinopyrido[3,4-d]pyrimidines as irreversible inhibitors of the erbB family of tyrosine kinase receptors Klutchko, SR; Zhou, HR; Winters, RT; Tran, TP; Bridges, AJ; Althaus, IW; Amato, DM; Elliott, WL; Ellis, PA; Meade, MA; Roberts, BJ; Fry, DW; Gonzales, AJ; Harvey, PJ; Nelson, JM; Sherwood, V; Han, HK; Pace, G; Smaill, JB; Denny, WA; Showalter, HDH 分享 收藏
Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6 Toogood, PL; Harvey, PJ; Repine, JT; Sheehan, DJ; VanderWel, SN; Zhou, HR; Keller, PR; McNamara, DJ; Sherry, D; Zhu, T; Brodfuehrer, J; Choi, C; Barvian, MR; Fry, DW 分享 收藏
Pyrido[2,3-d]pyrimidin-7-ones as specific inhibitors of cyclin-dependent kinase 4 VanderWel, SN; Harvey, PJ; McNamara, DJ; Repine, JT; Keller, PR; Quin, J; Booth, RJ; Elliott, WL; Dobrusin, EM; Fry, DW; Toogood, PL 分享 收藏
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Pyrido[2,3-d]pyrimidin-7-one inhibitors of cyclin-dependent kinases (vol 43, pg 4609, 2000) Barvian, M; Boschelli, DH; Cossrow, J; Dobrusin, E; Fattaey, A; Fritsch, A; Fry, D; Harvey, P; Keller, P; Garrett, M; La, F; Leopold, W; McNamara, D; Quin, M; Trumpp-Kallmeyer, S; Toogood, P; Wu, ZP; Zhang, EL 分享 收藏
Pyrido[2,3-d]pyrimidin-7-one inhibitors of cyclin-dependent kinases Barvian, M; Boschelli, DH; Cossrow, J; Dobrusin, E; Fattaey, A; Fritsch, A; Fry, D; Harvey, P; Keller, P; Garrett, M; La, F; Leopold, W; McNamara, D; Quin, M; Trumpp-Kallmeyer, S; Toogood, P; Wu, ZP; Zhang, EL 分享 收藏
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