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Bo-Chun Hu

Xuchang University

H指数:8

被引数:206

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Engineered BDH–NOx co-expression in Escherichia coli enables highly efficient in vivo cascade catalysis for the transformation of racemic epoxides to α-hydroxyketones

工程化BDH–NOx协同表达在Escherichia coli中实现了高效的原位级联催化，用于将外消旋环氧化物转化为α-羟基酮。

Journal of Biotechnology

IF3.9

2025-12-160

PRE

Significantly enhanced specific activity of Bacillus subtilis (2,3)-butanediol dehydrogenase through computer-aided refinement of its substrate-binding pocket

通过计算机辅助优化其底物结合口袋，显着增强了枯草芽孢杆菌 (2,3)-丁二醇脱氢酶的比活性

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2024-11-010

PRE

Regioselective inversion of an epoxide hydrolase by fine-tune its substrate-binding pocket for the production of (R)- and (S)-phenyl-1,2-ethanediol

MOLECULAR CATALYSIS

IF4.9

2024-10-010

PRE

Synthesis of α-hydroxy ketones through novel one-pot multi-enzyme cascade system from racemic epoxides

外消旋环氧化物通过新型一锅多酶级联系统合成 α-羟基酮

MOLECULAR CATALYSIS

IF4.9

2024-10-011

PRE

Comparative study on the target sequences of thaumatin-like protein (TLP) and internal transcribed spacer (ITS) in the detection of corn component in edible oil by ladder-shape melting temperature isothermal amplification (LMTIA)

LWT-FOOD SCIENCE AND TECHNOLOGY

IF6.6

2024-04-012

OAAI

Engineering a BsBDHA substrate-binding pocket entrance for the improvement in catalytic performance toward (R)-phenyl-1,2-ethanediol based on the computer-aided design

BIOCHEMICAL ENGINEERING JOURNAL

IF3.8

2023-05-014

PRE

Enantioconvergent hydrolysis of racemic epoxides at elevated concentrations in Tween-20/phosphate buffer by the corresponding epoxide hydrolases

PROCESS BIOCHEMISTRY

IF4

2022-04-015

PRE

Engineering the regiocomplementarity of an epoxide hydrolase from Rhodotorula paludigena by means of computer-aided design for the scale-up enantioconvergent hydrolysis of racemic m-nitrostyrene oxide

BIOCHEMICAL ENGINEERING JOURNAL

IF3.8

2022-03-017

PRE

Structure-Guided Regulation in the Enantioselectivity of an Epoxide Hydrolase to Produce Enantiomeric Monosubstituted Epoxides and Vicinal Diols via Kinetic Resolution

ORGANIC LETTERS

IF5

2022-03-0113

PRE

Structure-guided improvement in the enantioselectivity of an Aspergillus usamii epoxide hydrolase for the gram-scale kinetic resolution of ortho-trifluoromethyl styrene oxide

ENZYME AND MICROBIAL TECHNOLOGY

IF3.7

2021-05-016

PREAI

Nearly perfect kinetic resolution of racemic o-nitrostyrene oxide by AuEH2, a microsomal epoxide hydrolase from Aspergillus usamii, with high enantio- and regio-selectivity

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2021-02-014

PREAI

Efficient kinetic resolution of para-chlorostyrene oxide at elevated concentration by Solanum lycopersicum epoxide hydrolase in the presence of Tween-20

CATALYSIS COMMUNICATIONS

IF4.3

2021-01-015

OAAI

Greatly enhancing the enantioselectivity of PvEH2, a Phaseolus vulgaris epoxide hydrolase, towards racemic 1,2-epoxyhexane via replacing its partial cap-loop

通过替换其部分帽环，大大提高了菜豆环氧化物水解酶PvEH2对外消旋1，2-环氧己烷的对映选择性

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2020-08-0112

PREAI

Near-perfect kinetic resolution of o-methylphenyl glycidyl ether by RpEH, a novel epoxide hydrolase from Rhodotorula paludigena JNU001 with high stereoselectivity

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

IF4.3

2020-05-2811

PREAI

Near-perfect kinetic resolution of racemic p-chlorostyrene oxide by SIEH1, a novel epoxide hydrolase from Solanum lycopersicum with extremely high enantioselectivity

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2020-03-0115

PREAI

Characterization of a robust glucose 1-dehydrogenase, SyGDH, and its application in NADPH regeneration for the asymmetric reduction of haloketone by a carbonyl reductase in organic solvent/buffer system

PROCESS BIOCHEMISTRY

IF4

2020-02-017

PREAI

Manipulating the regioselectivity of aSolanum lycopersicumepoxide hydrolase for the enantioconvergent synthesis of enantiopure alkane- and alkene-1,2-diols

CATALYSIS SCIENCE & TECHNOLOGY

IF4.2

2020-01-017

PREAI

Manipulating regioselectivity of an epoxide hydrolase for single enzymatic synthesis of (R)-1,2-diols from racemic epoxides

CHEMICAL COMMUNICATIONS

IF4.2

2020-01-0127

PREAI

Substantially improving the enantioconvergence of PvEH1, a Phaseolus vulgaris epoxide hydrolase, towards m-chlorostyrene oxide by laboratory evolution

MICROBIAL CELL FACTORIES

IF4.9

2019-11-185

OAAI

Stereoselective ring-opening of styrene oxide at elevated concentration by Phaseolus vulgaris epoxide hydrolase, PvEH2, in the organic/aqueous biphasic system

CATALYSIS COMMUNICATIONS

IF4.3

2019-04-0110

PREAI