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M

Moaçir Wajner

instituto de ciências básicas da saúde

60H指数
739论文数
1.5W被引数
收录论文 233
发表时间
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L-carnitine modulates molecular responses associated with inflammation, endoplasmic reticulum stress, and neurotrophic signaling in cerebral cortex of neonatal Gcdh−/− mice exposed to glutaric and quinolinic acidsL-肉碱调节新生Gcdh−/−小鼠大脑皮层中与炎症、内质网应激和神经营养信号相关的分子反应，在暴露于戊二酸和喹啉酸时
errMetabolic Brain Disease
IF3.5
err2026-09-05
err0
errOAAI
errEdiandra Tissot Castro; Ângela Zanatta; Andrey Vinicios Soares Carvalho; Amanda Uggeri de Moraes; Carlos Alexandre Netto; Guilhian Leipnitz; Alexandre Umpierrez Amaral; Carmen Regla Vargas; Rafael Teixeira Ribeiro; Moacir Wajner
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Mitochondria-targeted reactive species scavenger JP4-039 protects against disturbances of redox homeostasis, mitochondrial quality control, and glucose metabolism in brains of glutaryl-CoA dehydrogenase-deficient mice: A potential new therapeutic strategy for glutaric acidemia type 1靶向线粒体的活性物质清除剂JP4-039可保护谷酰辅酶A脱氢酶缺陷小鼠大脑中氧化还原稳态、线粒体质量控制及葡萄糖代谢的紊乱：一种治疗戊二酸尿症I型的潜在新策略
errBiochemical Pharmacology
IF5.6
err2026-07-24
err0
PREAI
errRenata de Britto; Leonardo de Moura Alvorcem; Manuela Bianchin Marcuzzo; Rafael T. Ribeiro; Carolina Soares; Adriana Fernanda K. Vizuete; Larissa D. Bobermin; Gianina Teribele Venturin; Samuel Greggio; Eduardo R. Zimmer; André Quincozes-Santos; Diogo Onofre de Souza; Carlos-Alberto Gonçalves; Peter Wipf; Jerry Vockley; Bianca Seminotti; Moacir Wajner; Guilhian Leipnitz
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Ethylmalonic and Methylsuccinic Acids Disrupt Bioenergetics and Induce Mitochondrial Permeability Transition Through Thiol Redox Modulation in Rat Striatum: Potential Mechanisms Involved in Ethylmalonic Encephalopathy乙基丙二酸和甲基琥珀酸通过巯基氧化还原调控扰乱纹状体生物能量学并诱导线粒体渗透性转换：乙基丙二酸脑病潜在机制的探讨
errNeurochemical Research
IF3.8
err2026-05-27
err0
errOAAI
errManuela Bianchin Marcuzzo; Ângela Beatris Zemniaçak; Jaqueline Santana da Rosa; Bianca Silveira Signorini Verdi; Maria Paula Dalla Vechia Benati; Josyane de Andrade Silveira; Juliana Gomes do Nascimento; Helena de Almeida Moreira; Mateus Dias-Oliveira; Diogo Onofre Souza; Alexandre Umpierrez Amaral; Geancarlo Zanatta; Moacir Wajner; Guilhian Leipnitz
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Deleterious in vitro effects of ammonia and accumulated urea cycle amino acids on leukocyte DNA: assessment of the antioxidant effects of N-acetylcysteine and L-carnitine氨和积累的尿素循环氨基酸对白细胞DNA的有害体外效应：评估N-乙酰半胱氨酸和L-肉碱的抗氧化效应
errNaunyn-Schmiedeberg's Archives of Pharmacology
IF3.1
err2026-05-22
err0
PREAI
errFranciele Fátima Lopes; Jéssica Lamberty Faverzani; Bianca Gomes dos Reis; Ana Kalise Böttcher; Luisa Maria Bosquetti Tedesco; Stefani Altenhofen; Laura Smolski dos Santos; Gênifer Erminda Schreiner; Vanusa Manfredini; Moacir Wajner; Carmen Regla Vargas
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Nitrosative Stress Mediates Disruption of Redox Homeostasis and Oxidative Phosphorylation Caused by 3-Hydroxyisobutyric Acid in Cerebral Cortex of Developing Rats一氧化氮应激介导3-羟基异丁酸引起的发育期大鼠大脑皮层中氧化还原稳态和氧化磷酸化的破坏。
errMolecular Neurobiology
IF4.3
err2025-12-20
err0
PREAI
errRafael Teixeira Ribeiro; Rafael Palavro; Ângela Beatris Zeminiaçak; Ângela Zanatta; Ediandra Tissot Castro; Sâmela de Azevedo Cunha Cunha ; Tailine Quevedo Tavares; Alexandre Umpierrez Amaral; Guilhian Leipnitz; Moacir Wajner
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Neuroprotective, antioxidant and anti-inflammatory effect of carnitine in patients with Maple syrup urine disease: branched-chain amino acids and branched-chain keto acids levels肉碱在枫糖尿病患者中的神经保护、抗氧化和抗炎作用：支链氨基酸和支链酮酸水平
errMetabolic Brain Disease
IF3.5
err2025-11-15
err0
PREAI
errJúlia Girardi; Jéssica Lamberty Faverzani; Franciele Fátima Lopes; Angela Sitta; Daniella de Moura Coelho; Luísa Maria Bosquetti Tedesco; Natacha Dornelles; Moacir Wajner; Carmen Regla Vargas
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Nitisinone treatment protect hereditary tyrosinemia type I patients against inflammation, DNA and protein oxidative damage by decreasing succinylacetone levels尼替司农治疗通过降低琥珀酰乙酮水平，保护I型遗传性酪氨酸血症患者免受炎症、DNA和蛋白质氧化损伤。
errMetabolic Brain Disease
IF3.5
err2025-09-26
err0
PREAI
errRoberta Barbizan Mascarello; Jéssica Lamberty Faverzani; Franciele Fátima Lopes; Luísa Maria Bosquetti Tedesco; Ana Kalise Böttcher; Moacir Wajner; Carmen Regla Vargas
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Intracerebral Administration of Hydrogen Sulfide Impairs Bioenergetics, Redox Status and Mitochondrial Quality Control in Rat Striatum硫化氢的颅内给药损害大鼠纹状体的生物能量代谢、氧化还原状态和线粒体质量控制
errNeurotoxicity Research
IF3.3
err2025-09-20
err0
PREAI
errManuela Bianchin Marcuzzo; Josyane de Andrade Silveira; Camila Vieira Pinheiro; Jaqueline Santana da Rosa; Angela B. Zemniaçak; Morgana Brondani; Nathalia Simon Kist; Chrístofer Ian Hernandez Hoffmann; Helgi B. Schioth; Alexandre U. Amaral; Moacir Wajner; Guilhian Leipnitz
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Maternal lactoferrin supplementation prevents mitochondrial and redox homeostasis dysfunction, and improves antioxidant defenses through Nrf2 and UCP2 signaling after neonatal hypoxia-ischemia母体乳铁蛋白补充可预防新生儿缺氧缺血后的线粒体和氧化还原稳态功能障碍，并通过Nrf2和UCP2信号通路改善抗氧化防御能力。
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err2025-04-01
err1
PREAI
errCarvalho, Andrey Vinicios S.; Sanches, Eduardo F.; Ribeiro, Rafael T.; Duran-Carabali, Luz Elena; Ramires Junior, Osmar; Muniz, Bruna Dutra; Wajner, Moacir; Wyse, Angela T.; Netto, Carlos Alexandre; Sizonenko, Stephane V.
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Neuroprotective effects of L-carnitine towards oxidative stress and inflammatory processes: a review of its importance as a therapeutic drug in some disorders
errMETABOLIC BRAIN DISEASE
IF3.5
err2025-02-15
err0
PREAI
errGuerreiro, Gilian; Deon, Marion; Becker, Graziela Schmitt; dos Reis, Bianca Gomes; Wajner, Moacir; Vargas, Carmen Regla
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L-carnitine protects against oxidative damage and neuroinflammation in cerebral cortex of rats submitted to chronic chemically-induced model of hyperphenylalaninemia
errMETABOLIC BRAIN DISEASE
IF3.5
err2025-01-18
err0
PREAI
errFaverzani, Jessica Lamberty; Guerreiro, Gilian; Lopes, Franciele Fatima; Sitta, Angela; Coelho, Daniella de Moura; Mescka, Caroline Paula; Sehn, Luisa Degrandi; Rosa, Gabriel de Lima; de Lima, Amanda Muliterno Domingues Lourenco; Gonzalez, Esteban Alberto; Ribeiro, Rafael Teixeira; Palavro, Rafael; Coitinho, Adriana Simon; Baldo, Guilherme; Wajner, Moacir; Vargas, Carmen Regla
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α-Ketoisocaproic Acid Disrupts Mitochondrial Bioenergetics in the Brain of Neonate Rats: Molecular Modeling Studies of α-ketoglutarate Dehydrogenase Subunits Inhibition
errNEUROCHEMICAL RESEARCH
IF3.8
err2025-01-09
err0
PREAI
errZemniacak, angela Beatris; Ribeiro, Rafael Teixeira; das Neves, Gustavo Machado; Cunha, Samela de Azevedo; Tavares, Tailine Quevedo; Carvalho, Andrey Vinicios Soares; Netto, Carlos Alexandre; Castilho, Roger Frigerio; Wajner, Moacir; Amaral, Alexandre Umpierrez
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Protective effects of the PPAR agonist bezafibrate against disruption of redox and energy homeostasis, neuronal death, astroglial reactivity, and neuroinflammation induced in vivo by D-2-hydroxyglutaric acid in rat brain
errEUROPEAN JOURNAL OF PHARMACOLOGY
IF4.7
err2025-01-01
err0
PREAI
errRibeiro, Rafael Teixeira; Marcuzzo, Manuela Bianchin; Carvalho, Andrey Vinicios Soares; Palavro, Rafael; Castro, Ediandra Tissot; Pinheiro, Camila Vieira; Bobermin, Larissa Daniele; Amaral, Alexandre Umpierrez; Leipnitz, Guilhian; Netto, Carlos Alexandre; Wajner, Moacir
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Increased ROS levels, antioxidant defense disturbances and bioenergetic disruption induced by thiosulfate administration in the brain of neonatal rats
errMETABOLIC BRAIN DISEASE
IF3.5
err2024-12-20
err0
PREAI
errGlanzel, Nicolas Manzke; da Rosa-Junior, Nevton Teixeira; Signori, Marian F.; Silveira, Josyane de Andrade; Pinheiro, Camila Vieira; Marcuzzo, Manuela Bianchin; Campos-Carraro, Cristina; Araujo, Alex Sander da Rosa; Schioth, Helgi B.; Wajner, Moacir; Leipnitz, Guilhian
err分享
err收藏
Impairment of neuromotor development and cognition associated with histopathological and neurochemical abnormalities in the cerebral cortex and striatum of glutaryl-CoA dehydrogenase deficient mice
errNEUROCHEMISTRY INTERNATIONAL
IF4
err2024-12-01
err0
PREAI
errCastro, Ediandra Tissot; Ribeiro, Rafael Teixeira; Carvalho, Andrey Vinicios Soares; Machado, Diorlon Nunes; Zemniacak, Angela Beatris; Palavro, Rafael; Cunha, Samela de Azevedo; Tavares, Tailine Quevedo; Souza, Diogo Onofre Gomes de; Netto, Carlos Alexandre; Leipnitz, Guilhian; Amaral, Alexandre Umpierrez; Wajner, Moacir
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Neurodegenerative biomarkers and inflammation in patients with propionic and methylmalonic acidemias: effect of L-carnitine treatment
errMETABOLIC BRAIN DISEASE
IF3.5
err2024-11-16
err0
PREAI
errdos Reis, Bianca Gomes; Becker, Graziela Schmitt; Marchetti, Desiree Padilha; Coelho, Daniella de Moura; Sitta, Angela; Wajner, Moacir; Vargas, Carmen Regla
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err收藏
3-Hydroxy-3-Methylglutaric Acid Disrupts Brain Bioenergetics, Redox Homeostasis, and Mitochondrial Dynamics and Affects Neurodevelopment in Neonatal Wistar Rats3-羟基-3-甲基戊二酸会破坏新生Wistar大鼠的脑生物能，氧化还原稳态和线粒体动力学，并影响神经发育
errBIOMEDICINES
IF3.9
err2024-07-15
err1
errOAAI
errSilveira, Josyane de Andrade; Marcuzzo, Manuela Bianchin; da Rosa, Jaqueline Santana; Kist, Nathalia Simon; Hoffmann, Christofer Ian Hernandez; Carvalho, Andrey Soares; Ribeiro, Rafael Teixeira; Quincozes-Santos, Andre; Netto, Carlos Alexandre; Wajner, Moacir; Leipnitz, Guilhian
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Glycine disrupts myelin, glutamatergic neurotransmission, and redox homeostasis in a neonatal model for non ketotic hyperglycinemia甘氨酸在非酮症性高血糖症的新生儿模型中破坏髓磷脂，谷氨酸能神经传递和氧化还原稳态
errBIOCHIMIE
IF3
err2024-04-01
err1
PREAI
errParmeggiani, Belisa; Signori, Marian Flores; Cecatto, Cristiane; Frusciante, Marina Rocha; Marcuzzo, Manuela Bianchin; Souza, Debora Guerini; Ribeiro, Rafael Teixeira; Seminotti, Bianca; de Souza, Diogo Onofre Gomes; Ribeiro, Cesar Augusto Joa o; Wajner, Moacir; Leipnitz, Guilhian
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Disturbances in mitochondrial bioenergetics and control quality and unbalanced redox homeostasis in the liver of a mouse model of mucopolysaccharidosis type IIII型粘多糖贮积症小鼠模型肝脏中线粒体生物能学的紊乱，控制质量和不平衡的氧化还原稳态
errMOLECULAR AND CELLULAR BIOCHEMISTRY
IF3.7
err2024-03-18
err2
PREAI
errPinheiro, Camila Vieira; Ribeiro, Rafael Teixeira; Roginski, Ana Cristina; Brondani, Morgana; Zemniacak, angela Beatris; Hoffmann, Christofer Ian Hernandez; Amaral, Alexandre Umpierrez; Wajner, Moacir; Baldo, Guilherme; Leipnitz, Guilhian
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Disturbance of mitochondrial functions caused by N-acetylglutamate and N-acetylmethionine in brain of adolescent rats: Potential relevance in aminoacylase 1 deficiency青春期大鼠大脑中N-乙酰谷氨酸和N-乙酰蛋氨酸引起的线粒体功能紊乱: 氨基酰化酶1缺乏症的潜在相关性
errNEUROCHEMISTRY INTERNATIONAL
IF4
err2023-12-01
err0
PREAI
errBortoluzzi, Vanessa Trindade; Ribeiro, Rafael Teixeira; Zemniacak, Angela Beatris; Cunha, Samela de Azevedo; Sass, Joern Oliver; Castilho, Roger Frigerio; Amaral, Alexandre Umpierrez; Wajner, Moacir
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