Takuya Noguchi

Tohoku University

H指数:44

被引数:7,799

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AMPK Limits MNNG-Induced Parthanatos by Inhibiting BH3-Only Protein Bim

AMPK通过抑制BH3-Only蛋白Bim限制MNNG诱导的Parthanatos

International Journal of Molecular Sciences

IF4.9

2026-03-030

OAAI

Identification of MKRN1 as a key modulator of the p53-MDM2 feedback loop

cell death & differentiation

IF0

2026-01-300

OAAI

FBXO22 Suppresses Oxidative Stress-Induced ASK1 Activation and Cell Death via Ubiquitination-Dependent Degradation of TRIM48

FBXO22通过泛素化依赖性降解TRIM48，抑制氧化应激诱导的ASK1激活和细胞死亡。

International Journal of Molecular Sciences 2025, Vol. 26, Page 9472

IF4.9

2025-09-280

OAAI

Elaidic acid drives cellular senescence and inflammation via lipid raft-mediated IL-1R signaling

反式油酸通过脂筏介导的白介素1受体（IL-1R）信号通路驱动细胞衰老和炎症。

iScience

IF4.1

2025-08-060

Frequency-Regulated Repeated Micro-Vibration Promotes Osteoblast Differentiation Through BMP Signaling in MC3T3-E1 Cells

频率调节的重复性微振动通过BMP信号通路促进MC3T3-E1细胞中成骨细胞分化

LIFE-BASEL

IF3.4

2025-04-030

The Selective 3-MST Inhibitor I3MT-3 Works as a Potent Caspase-1 Inhibitor

选择性3-MST抑制剂I3MT-3作为有效的半胱天冬酶-1抑制剂

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-03-020

Conjugated fatty acids drive ferroptosis through chaperone-mediated autophagic degradation of GPX4 by targeting mitochondria

共轭脂肪酸通过靶向线粒体通过伴侣介导的GPX4自噬降解驱动铁死亡

CELL DEATH & DISEASE

IF9.6

2024-12-061

OAAI

Roquin-2 promotes oxidative stress-induced cell death by ubiquitination-dependent degradation of TAK1

Roquin-2通过泛素化依赖的TAK1降解促进氧化应激诱导的细胞死亡

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2024-08-011

OAAI

The NLRP3 Inflammasome Is a Major Cause of Acute Renal Failure Induced by Polypeptide Antibiotics

JOURNAL OF IMMUNOLOGY

IF3.4

2024-04-194

PRE

The E3 Ubiquitin Protein Ligase LINCR Amplifies the TLR-Mediated Signals through Direct Degradation of MKP1

CELLS

IF5.2

2024-04-152

OAAI

Aggregability of the SQSTM1/p62-based aggresome-like induced structures determines the sensitivity to parthanatos

CELL DEATH DISCOVERY

IF7

2024-02-120

OAAI

LLPS of SQSTM1/p62 and NBR1 as outcomes of lysosomal stress response limits cancer cell metastasis

作为溶酶体应激反应的结果，SQSTM1/p62和NBR1的LLPS限制了癌细胞的转移

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-10-1711

OAAI

Geometrical isomerization of arachidonic acid during lipid peroxidation interferes with ferroptosis

脂质过氧化过程中花生四烯酸的几何异构化会干扰铁死亡

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2023-08-0110

OAAI

Reactive sulfur species disaggregate the SQSTM1/p62-based aggresome-like induced structures via the HSP70 induction and prevent parthanatos

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-06-014

OAAI

Methylmercury directly modifies the 105th cysteine residue in oncostatin M to promote binding to tumor necrosis factor receptor 3 and inhibit cell growth

ARCHIVES OF TOXICOLOGY

IF6.9

2023-05-171

PRE

A comprehensive toxicological analysis of trans-fatty acids (TFAs) reveals a pro-apoptotic action specific to industrial TFAs counteracted by polyunsaturated FAs

SCIENTIFIC REPORTS

IF3.9

2023-04-116

OAAI

Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27259

OAAI

The NLRP3 Inflammasome Works as a Sensor for Detecting Hypoactivity of the Mitochondrial Src Family Kinases

JOURNAL OF IMMUNOLOGY

IF3.4

2023-03-159

PRE

trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway

SCIENTIFIC REPORTS

IF3.9

2021-05-1415

OAAI

Methylmercury induces neuronal cell death by inducing TNF-α expression through the ASK1/p38 signaling pathway in microglia

SCIENTIFIC REPORTS

IF3.9

2021-05-1020

OAAI

Takuya Noguchi

个人简介

教育背景

工作经历

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