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Lilan Xin

zhongnan hospital of wuhan university and wuhan university

9H指数
27论文数
183被引数
收录论文 17
发表时间
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A distinct zearalenone detoxification strategy mediated by cytochrome P450一种由细胞色素P450介导的独特玉米赤霉烯酮解毒策略
errFood Chemistry
IF9.8
err2026-03-03
err0
PREAI
errZiwei Liu; Rouming Peng; Qian Li; Chun-Chi Chen; Lilan Xin; Kangkang Li; Jian-Wen Huang; Xin Liu; Xiaodong Zhang; Linzhen Hu; Shangwen Luo; Haibing Zhou; Aitao Li; Jian Min; Rey-Ting Guo
err分享
err收藏
Hydrophobic tagging: A promising paradigm for targeted protein degradation
errCell Insight
IF0
err2025-12-01
err1
errOAAI
errXin, Lilan; Wang, Hongli; Yang, Maoze; Guo, Zhangxiao; Zhu, Man; Moore, Terry W.; Dong, Chune; Zhou, Hai-Bing
err分享
err收藏
Discovery of ERα-targeting PROTACs with intrinsic fluorescence for precision theranostics of breast cancer具有固有荧光的ERα靶向PROTACs在乳腺癌精准诊疗中的发现
errRSC Med. Chem.
IF3.6
err2025-08-14
err0
PREAI
errYihe Wu ‡; Junhong Dai ‡; Xiaofei Deng; Pei He; Jinsen Liang; Lilan Xin; Baohua Xie; Shenghong Zhu; Chune Dong; Hai-Bing Zhou
err分享
err收藏
The discovery of acyl thiourea derivatives as potent hydrophobic tagging degraders targeting SIRT2 for the treatment of ovarian cancer酰基硫脲衍生物作为靶向SIRT2的强效疏水标签降解剂在卵巢癌治疗中的发现
errChinese Chemical Letters
IF8.9
err2025-03-26
err0
PREAI
errDandan Wang; Xiaoyu Ma; Yijin Zhao; Wenting Zou; Hua Wang; Yang Gao; Shimeng Wan; Jian Ni; Lilan Xin; Hai-Bing Zhou; Hongbing Cai; Chune Dong
err分享
err收藏
Pegylated NIR Fluorophore-Conjugated OBHSA Prodrug for ERα-Targeted Theranostics with Enhanced Imaging and Long-Term Retention
errMOLECULES
IF4.6
err2025-01-14
err0
errOAAI
errWang, Xiaohua; Deng, Xiaofei; Xin, Lilan; Dong, Chune; Hu, Guoyuan; Zhou, Hai-Bing
err分享
err收藏
Structure-guided identification of novel dual-targeting estrogen receptor α degraders with aromatase inhibitory activity for the treatment of endocrine-resistant breast cancer (vol 253, 115328, 2023)
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-10-01
err0
PREAI
errXin, Lilan; Min, Jian; Hu, Hebing; Li, Yuanyuan; Du, Chuanqian; Xie, Baohua; Cheng, Yan; Deng, Xiaofei; Deng, Xiangping; Shen, Kang; Huang, Jian; Chen, Chun-Chi; Guo, Rey-Ting; Dong, Chune; Zhou, Hai-Bing
err分享
err收藏
Novel Hsp90-Targeting PROTACs: Enhanced synergy with cisplatin in combination therapy of cervical cancer
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-09-01
err5
PREAI
errLiang, Jinsen; Wang, Dandan; Zhao, Yijin; Wu, Yihe; Liu, Xuelian; Xin, Lilan; Dai, Junhong; Ren, Hang; Zhou, Hai-Bing; Cai, Hongbing; Dong, Chune
err分享
err收藏
FLT3-selective PROTAC: Enhanced safety and increased synergy with Venetoclax in FLT3-ITD mutated acute myeloid leukemia
errCANCER LETTERS
IF10.1
err2024-06-01
err3
PREAI
errTan, Yuxin; Xin, Lilan; Wang, Qian; Xu, Rong; Tong, Xiqin; Chen, Guopeng; Ma, Linlu; Yang, Fuwei; Jiang, Hongqiang; Zhang, Nan; Wu, Jinxian; Li, Xinqi; Guo, Xinyi; Wang, Chao; Zhou, Haibing; Zhou, Fuling
err分享
err收藏
Discovery of Novel ERα and Aromatase Dual-Targeting PROTAC Degraders to Overcome Endocrine-Resistant Breast Cancer
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-05-29
err3
PREAI
errXin, Lilan; Wang, Chao; Cheng, Yan; Wang, Hongli; Guo, Xinyi; Deng, Xiaofei; Deng, Xiangping; Xie, Baohua; Hu, Hankun; Min, Chang; Dong, Chune; Zhou, Hai-Bing
err分享
err收藏
Novel Acyl Thiourea-Based Hydrophobic Tagging Degraders Exert Potent Anti-Influenza Activity through Two Distinct Endonuclease Polymerase Acidic-Targeted Degradation Pathways
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-05-22
err2
PREAI
errMa, Xiaoyu; Wang, Xueyun; Chen, Feifei; Zou, Wenting; Ren, Junrui; Xin, Lilan; He, Pei; Liang, Jinsen; Xu, Zhichao; Dong, Chune; Lan, Ke; Wu, Shuwen; Zhou, Hai-Bing
err分享
err收藏
Novel estrogen receptor β/histone deacetylase dual-targeted near-infrared fluorescent probes as theranostic agents for imaging and treatment of prostate cancer新型雌激素受体 β/组蛋白去乙酰化酶双靶向近红外荧光探针作为前列腺癌成像和治疗的治疗剂
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-03-01
err3
PREAI
errHe, Pei; Yu, Huiguang; Deng, Xiaofei; Xin, Lilan; Xu, Bin; Zhou, Hai-Bing; Dong, Chune
err分享
err收藏
Fluorescence theranostic PROTACs for real-time visualization of ERα degradation
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-03-01
err3
PREAI
errWang, Xiaohua; Xin, Lilan; Deng, Xiaofei; Dong, Chune; Hu, Guoyuan; Zhou, Hai-Bing
err分享
err收藏
Identification of Novel Dual-Target Estrogen Receptor α Degraders with Tubulin Inhibitory Activity for the Treatment of Endocrine-Resistant Breast Cancer
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-08-16
err7
PREAI
errDeng, Xiangping; Deng, Xiaofei; Ning, Wentao; Xin, Lilan; Li, Qiuzi; Hu, Zhiye; Xie, Baohua; Liang, Kaiwei; Min, Chang; Dong, Chune; Huang, Jian; Zhou, Hai-Bing
err分享
err收藏
Structure-guided identification of novel dual-targeting estrogen receptor α degraders with aromatase inhibitory activity for the treatment of endocrine-resistant breast cancer
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-05-01
err12
errOAAI
errXin, Lilan; Min, Jian; Hu, Hebing; Li, Yuanyuan; Du, Chuanqian; Xie, Baohua; Cheng, Yan; Deng, Xiaofei; Deng, Xiangping; Shen, Kang; Huang, Jian; Chen, Chun -Chi; Guo, Rey-Ting; Dong, Chune; Zhou, Hai -Bing
err分享
err收藏
A novel selective estrogen receptor degrader induces cell cycle arrest in breast cancer via ER? degradation and the autophagy-lysosome pathway
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2023-03-01
err5
PREAI
errZhou, Jiawei; Shen, Rong; Liu, Jing; Deng, Xiangping; Xin, Lilan; Zhou, Hai-Bing; Huang, Jian
err分享
err收藏
Novel hybrid conjugates with dual estrogen receptor α degradation and histone deacetylase inhibitory activities for breast cancer therapy
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2021-06-01
err7
PREAI
errZhao, Chenxi; Tang, Chu; Li, Changhao; Ning, Wentao; Hu, Zhiye; Xin, Lilan; Zhou, Hai-Bing; Huang, Jian
err分享
err收藏
err
IF0
err
err0
PREAI
err
err分享
err收藏

研究方向

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合作学者
合作期刊
刘
刘佳 (Jing Liu)
H 指数: 63 · 论文数: 371
Kang Shen 封面图
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H 指数: 63 · 论文数: 272
王超 封面图
王超 (Chao Wang)
H 指数: 53 · 论文数: 500
蓝柯 封面图
蓝柯 (Ke Lan)
H 指数: 50 · 论文数: 334
D
Dandan Wang
H 指数: 50 · 论文数: 270
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