Prem Ponka - Publications, H-index & Citations

Prem Ponka

lady davis institute

56H指数

210论文数

1.4W被引数

收录论文 51

发表时间

Unraveling mechanisms regulating erythroid iron metabolism

CLINICA CHIMICA ACTA

IF2.9

2024-05-01

PREAI

Hamdi, A.; Tahtouh, T.; Garcia, D. Santos; Blank, V.; Ponka, P.

S-nitrosylation of IRP2 regulates its stability via the ubiquitin-proteasome pathway

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Kim, S; Wing, SS; Ponka, P

Nrf2 controls iron homoeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin

NATURE METABOLISM

IF20.8

2019-05-13

105

OAAI

Lim, Pei Jin; Duarte, Tiago L.; Arezes, Joao; Garcia-Santos, Daniel; Hamdi, Amel; Pasricha, Sant-Rayn; Armitage, Andrew E.; Mehta, Hema; Wideman, Sarah; Santos, Ana G.; Santos-Goncalves, Andreia; Morovat, Alireza; Hughes, Jim R.; Soilleux, Elizabeth; Wang, Chia-Yu; Bayer, Abraham L.; Klenerman, Paul; Willberg, Christian B.; Hartley, Richard C.; Murphy, Michael P.; Babitt, Jodie L.; Ponka, Prem; Porto, Graca; Drakesmith, Hal

Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells

HAEMATOLOGICA

IF7.9

2017-05-11

OAAI

Garcia-Santos, Daniel; Schranzhofer, Matthias; Bergeron, Richard; Sheftel, Alex D.; Ponka, Prem

Do Mammalian Cells Really Need to Export and Import Heme?

TRENDS IN BIOCHEMICAL SCIENCES

IF11

2017-05-01

PREAI

Ponka, Prem; Sheftel, Alex D.; English, Ann M.; Bohle, D. Scott; Garcia-Santos, Daniel

Response to: Dietary and pharmacological factors affecting iron absorption in mice and man

HAEMATOLOGICA

IF7.9

2016-02-29

OAAI

Fillebeen, Carine; Gkouvatsos, Konstantinos; Fragoso, Gabriela; Calve, Annie; Garcia-Santos, Daniel; Buffler, Marzell; Becker, Christiane; Schuemann, Klaus; Ponka, Prem; Santos, Manuela M.; Pantopoulos, Kostas

Hepcidin Bound to α2-Macroglobulin Reduces Ferroportin-1 Expression and Enhances Its Activity at Reducing Serum Iron Levels 与 α2-巨球蛋白结合的铁调素可降低Ferroportin-1表达并增强其降低血清铁水平的活性

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-08-01

OAAI

Huang, Michael Li-Hsuan; Austin, Christopher J. D.; Sari, Marie-Agnes; Rahmanto, Yohan Suryo; Ponka, Prem; Vyoral, Daniel; Richardson, Des R.

Nitrogen monoxide inhibits haem synthesis in mouse reticulocytes 一氧化氮抑制小鼠网织红细胞中的血红素合成

BIOCHEMICAL JOURNAL

IF4.3

2013-03-14

PREAI

Mikhael, Marc R.; Soe-Lin, Shan; Apte, Sameer; Ponka, Prem

Snx3 Regulates Recycling of the Transferrin Receptor and Iron Assimilation Snx3调节转铁蛋白受体的再循环和铁同化

CELL METABOLISM

IF30.9

2013-03-01

111

OAAI

Chen, Caiyong; Garcia-Santos, Daniel; Ishikawa, Yuichi; Seguin, Alexandra; Li, Liangtao; Fegan, Katherine H.; Hildick-Smith, Gordon J.; Shah, Dhvanit I.; Cooney, Jeffrey D.; Chen, Wen; King, Matthew J.; Yien, Yvette Y.; Schultz, Iman J.; Anderson, Heidi; Dalton, Arthur J.; Freedman, Matthew L.; Kingsley, Paul D.; Palis, James; Hattangadi, Shilpa M.; Lodish, Harvey F.; Ward, Diane M.; Kaplan, Jerry; Maeda, Takahiro; Ponka, Prem; Paw, Barry H.

Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia 在Friedreich共济失调的小鼠模型中鉴定非铁蛋白线粒体铁沉积物

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2012-11-20

OAAI

Whitnall, Megan; Rahmanto, Yohan Suryo; Huang, Michael L. -H.; Saletta, Federica; Lok, Hiu Chuen; Gutierrez, Lucia; Lazaro, Francisco J.; Fleming, Adam J.; St Pierre, Tim G.; Mikhael, Marc R.; Ponka, Prem; Richardson, Des R.

Iron Overload in Human Disease 铁过载与人类疾病

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2012-01-26

510

PREAI

Fleming, Robert E.; Ponka, Prem

Nitric Oxide Storage and Transport in Cells Are Mediated by Glutathione S-Transferase P1-1 and Multidrug Resistance Protein 1 via Dinitrosyl Iron Complexes 谷胱甘肽S-转移酶P1-1和多药耐药蛋白1通过二亚硝酰铁复合物介导一氧化氮在细胞中的储存和运输

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2012-01-01

OAAI

Lok, Hiu Chuen; Rahmanto, Yohan Suryo; Hawkins, Clare L.; Kalinowski, Danuta S.; Morrow, Charles S.; Townsend, Alan J.; Ponka, Prem; Richardson, Des R.

Antitumor Activity of Metal-Chelating Compound Dp44mT Is Mediated by Formation of a Redox-Active Copper Complex That Accumulates in Lysosomes 金属螯合化合物Dp44mT的抗肿瘤活性是由溶酶体中积累的氧化还原活性铜复合物的形成介导的

CANCER RESEARCH

IF16.6

2011-08-30

269

OAAI

Lovejoy, David B.; Jansson, Patric J.; Brunk, Ulf T.; Wong, Jacky; Ponka, Prem; Richardson, Des R.

Hypoxia. 5. Hypoxia and hematopoiesis 缺氧和造血

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2011-06-01

PREAI

Yoon, Donghoon; Ponka, Prem; Prchal, Josef T.

Antagonistic roles of the ERK and p38 MAPK signalling pathways in globin expression, haem biosynthesis and iron uptake ERK和p38 MAPK信号通路在珠蛋白表达，血红素生物合成和铁摄取中的拮抗作用

BIOCHEMICAL JOURNAL

IF4.3

2010-10-25

PREAI

Mardini, Louay; Gasiorek, Jadwiga; Derjuga, Anna; Carriere, Lucie; Schranzhofer, Matthias; Paw, Barry H.; Ponka, Prem; Blank, Volker

Lysosomal Proteolysis Is the Primary Degradation Pathway for Cytosolic Ferritin and Cytosolic Ferritin Degradation Is Necessary for Iron Exit 溶酶体蛋白水解是胞质铁蛋白的主要降解途径，而胞质铁蛋白降解是铁排出所必需的

ANTIOXIDANTS & REDOX SIGNALING

IF6.1

2010-10-01

111

PREAI

Zhang, Yinghui; Mikhael, Marc; Xu, Dongxue; Li, Yiye; Shan Soe-Lin; Ning, Bo; Li, Wei; Nie, Guangjun; Zhao, Yuliang; Ponka, Prem

Ferritin does not donate its iron for haem synthesis in macrophages 铁蛋白不会为巨噬细胞中的血红素合成提供铁

BIOCHEMICAL JOURNAL

IF4.3

2010-07-14

PREAI

Mikhael, Marc; Sheftel, Alex D.; Ponka, Prem

Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol 线粒体铁的运输以及线粒体与胞质之间铁代谢的整合

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2010-05-21

446

OAAI

Richardson, Des R.; Lane, Darius J. R.; Becker, Erika M.; Huang, Michael L. -H.; Whitnall, Megan; Rahmanto, Yohan Suryo; Sheftel, Alex D.; Ponka, Prem

Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant 通过分析小鼠突变体阐明弗里德赖希共济失调中线粒体铁负荷的机制

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2009-09-22

206

OAAI

Huang, Michael Li-Hsuan; Becker, Erika M.; Whitnall, Megan; Rahmanto, Yohan Suryo; Ponka, Prem; Richardson, Des R.

Overexpression of Mitochondrial Ferritin Sensitizes Cells to Oxidative Stress Via an Iron-Mediated Mechanism 线粒体铁蛋白的过表达通过铁介导的机制使细胞对氧化应激敏感

ANTIOXIDANTS & REDOX SIGNALING

IF6.1

2009-08-01

PREAI

Lu, Zhongbing; Nie, Guangjun; Li, Yiye; Soe-lin, Shan; Tao, Yi; Cao, Yuanlin; Zhang, Zhiyong; Liu, Nianqing; Ponka, Prem; Zhao, Baolu

研究方向