Philip A. Efron - Publications, H-index & Citations

Philip A. Efron

State University System of Florida

60H指数

440论文数

1.4W被引数

收录论文 185

发表时间

Preterm birth skews the developmental trajectory of myeloid-derived suppressor cells in the first 48 hours of life: single-cell transcriptomics and inferred intercellular communication 早产导致髓系来源抑制细胞在生命最初48小时内的发育轨迹发生偏移：单细胞转录组学和推断的细胞间通讯

Molecular Medicine

IF6.4

2026-03-27

OAAI

Miguel Hernández-Ríos; Jaimar Rincon; Leandro Balzano-Nogueira; Valerie Polcz; Dayuan Wang; Whitman Wiggins; Christine Rodhouse; Athina Yoham; Feifei Xiao; Ricardo Ungaro; Marvin Dirain; Lyle Moldawer; Robert Maile; Guoshuai Cai; Philip Efron; Shawn Larson

A murine model of sepsis induces age- and sex-specific chromatin remodeling in myeloid-derived suppressor cells 脓毒症小鼠模型诱导髓源抑制细胞发生年龄和性别特异的染色质重塑

Frontiers in Immunology

IF5.9

2026-03-26

OAAI

AM Angel M. Charles; CE Christine E. Rodhouse; DB Dijoia B. Darden; ML Marie-Pierre L. Gauthier; MZ Mingqi Zhou †; MH Miguel Hernandez-Rios; DW Dayuan Wang; GC Gemma Casadesus; LB Letitia Bible; AM Alicia M. Mohr; FX Feifei Xiao; GC Guoshuai Cai; JO Jason O. Brant; SM Shannon M. Wallet; CE Clayton E. Mathews; LL Lyle L. Moldawer; PC Paramita Chakrabarty; RL Rhonda L. Bacher; PA Philip A. Efron; RM Robert Maile; MP Michael P. Kladde ‡

Interaction of Sepsis, Disuse, and Aging on Skeletal Muscle Function and Remodeling in Male and Female Mice 脓毒症、废用及衰老对雄性和雌性小鼠骨骼肌功能与重塑的影响

Acta Physiologica

IF5.6

2026-03-18

PREAI

Diana C. Muller; Franccesco P. Boeno; Gisienne Reis; Armina Azam; Malaica Ashley; Yumei Zhou; Feng Yue; Terence E. Ryan; Philip A. Efron; Orlando Laitano

Chromatin Remodeling and Transcriptional Silencing Define the Dynamic Innate Immune Response of Tissue Resident Macrophages After Burn Injury 染色质重塑和转录沉默定义了组织驻留巨噬细胞在烧伤损伤后的动态固有免疫应答

Shock

IF2.9

2026-03-01

PREAI

Kim, Han G.; Gauthier, Marie-Pierre L.; Higgs, Aidan; Hernandez, Denise A.; Zhou, Mingqi; Brant, Jason O.; Bacher, Rhonda L.; Darden, Dijoia B.; Wallet, Shannon M.; Mathews, Clayton E.; Moldawer, Lyle L.; Efron, Philip A.; Kladde, Michael P.; Maile, Robert

Macrophages Polarization as a Potential Driver and a Therapeutic Target for Sepsis-induced Cognitive Impairment in Older Adults 巨噬细胞极化作为脓毒症诱导的老年人认知障碍的潜在驱动因素和治疗靶点

Shock

IF2.9

2026-02-01

PREAI

Zeidan, Rola S.; Reinhard, Simon; Sykes, Shannon; Price, Catherine; Wallet, Shannon; Maile, Robert; Efron, Philip; Mankowski, Robert T.; Anton, Stephen

Spatial single-cell multiomics reveals peripheral immune dysfunction in Parkinson’s and inflammatory bowel disease 空间单细胞多组学揭示帕金森病和炎症性肠病的外周免疫功能障碍

npj Parkinson's Disease

IF8.2

2026-01-16

OAAI

MacKenzie L. Bolen; Marc Buendia; Ji Shi; Hannah Staley; Jennifer M. Kachergus; Philip A. Efron; Gwoncheol Park; Ravinder Nagpal; Stephan D. Alvarez; Qing-Shan Xue; Nikolaus R. McFarland; Ellen M. Zimmermann; Christopher E. Forsmark; Kelly B. Menees; Azucena Salas; E. Aubrey Thompson; Malú Gámez Tansey

Sepsis-induced systemic inflammation and tau pathology examined in the PS19 transgenic mouse model 脓毒症诱导的全身性炎症和tau病理在PS19转基因小鼠模型中的研究

Alzheimer's & Dementia

IF0

2025-12-25

OAAI

Quan Vo; Dina Nacionales; Kristi Biswas; Carmelina Gorski; Lyle L Moldawer; Philip A Efron; Paramita Chakrabarty

DAMP-driven trained immunity: metabolic and epigenetic reprogramming in critical illness and chronic inflammation DAMP驱动的训练性免疫：危重病和慢性炎症中的代谢与表观遗传重编程

Frontiers in Immunology

IF5.9

2025-11-24

OAAI

Han G. Kim; Jaimar C. Rincon; Philip A. Efron; Robert Maile

Author Correction: A consensus immune dysregulation framework for sepsis and critical illnesses 作者更正：脓毒症和危重疾病的共识免疫失调框架

Nature Medicine

IF50

2025-10-27

OAAI

Andrew R. Moore; Hong Zheng; Ananthakrishnan Ganesan; Yehudit Hasin-Brumshtein; Manoj V. Maddali; Joseph E. Levitt; Tom van der Poll; Jingyi Lu; Hjalmar R. Bouma; Brendon P. Scicluna; Evangelos J. Giamarellos-Bourboulis; Antigone Kotsaki; Ignacio Martin-Loeches; Alexis Garduno; Jeremiah Hinson; Richard E. Rothman; Jonathan Sevransky; David W. Wright; Mihir R. Atreya; Lyle L. Moldawer; Philip A. Efron; Marcela Kralovcova; Thomas Karvunidis; Heather M. Giannini; Nuala J. Meyer; Timothy E. Sweeney; Angela J. Rogers; Purvesh Khatri

Short-Course Antibiotic Agent Therapy for Early Ventilator-Associated Pneumonia in Patients with Trauma 创伤患者早期呼吸机相关性肺炎的短程抗生素治疗

SURGICAL INFECTIONS

IF0

2025-09-01

PREAI

Shoulders, Bethany R.; Fassler, Anne-Marie; Maguigan, Kelly L.; Loftus, Tyler J.; Efron, Philip A.; Mohr, Alicia M.; Vanzant, Erin

Temporal impact of sepsis on Alzheimer's disease pathology and neuroinflammation 脓毒症对阿尔茨海默病病理和神经炎症的时间影响

PROGRESS IN NEUROBIOLOGY

IF6.1

2025-07-01

OAAI

Quan Vo; Dina C. Nacionales; Karen N. McFarland; Carmelina Gorski; Evan L. Barrios; Gwoncheol Park; Lyle L. Moldawer; Gemma Casadesus; Ravinder Nagpal; Philip A. Efron; Paramita Chakrabarty

Innate immune training in the neonatal response to sepsis 新生儿对脓毒症的反应中的先天免疫训练

MOLECULAR MEDICINE

IF6.4

2025-04-30

OAAI

Rincon, Jaimar C.; Wang, Dayuan; Polcz, Valerie E.; Barrios, Evan L.; Dirain, Marvin L.; Ungaro, Ricardo F.; Nacionales, Dina C.; Zeumer-Spataro, Leilani; Xiao, Feifei; Efron, Philip A.; Moldawer, Lyle L.; Cai, Guoshuai; Larson, Shawn D.

Determining potential immunomodulatory drug efficacy in sepsis using ELISpot 利用ELISpot确定脓毒症中潜在免疫调节药物的疗效

SCIENTIFIC REPORTS

IF3.9

2025-04-18

OAAI

Walton, Andrew H.; Mazer, Monty B.; Remy, Kenneth E.; Osborne, Dale F.; Davitt, Ethan B.; Griffith, Thomas S.; Gould, Robert W.; Badovinac, Vladimir P.; Brakenridge, Scott C.; Drewry, Anne M.; Ungaro, Ricardo F.; Rocha, Ivanna L.; Loftus, Tyler J.; Efron, Philip A.; Moldawer, Lyle L.; Caldwell, Charles C.

Functional connectivity within sensorimotor cortical and striatal regions is regulated by sepsis in a sex-dependent manner (vol 305, 120995, 2025)脓毒症以性别依赖的方式调节感觉运动皮层和纹状体区域内的功能连接（vol 305, 120995, 2025）

NEUROIMAGE

IF4.5

2025-03-01

OAAI

Vo, Quan; Simon, Zachary D.; Park, Gwoncheol; Nacionales, Dina C.; Gorski, Carmelina; Barrios, Evan L.; Casadesus, Gemma; Efron, Philip A.; Moldawer, Lyle L.; Nagpal, Ravinder; Febo, Marcelo

Investigating Sepsis-Associated Delirium Through Optical Neuroimaging: A New Frontier in Critical Care Research

CHEMOSENSORS

IF3.7

2024-12-15

OAAI

Jiang, Shixie; Gunther, Matthew; Maldonado, Jose R.; Efron, Philip A.; Dekosky, Steven T.; Jiang, Huabei

Unique lymphocyte transcriptomic profiles in septic patients with chronic critical illness

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-12-03

OAAI

Barrios, Evan L.; Balzano-Nogueira, Leandro; Polcz, Valerie E.; Rodhouse, Christine; Leary, Jack R.; Darden, Dijoia B.; Rincon, Jaimar C.; Dirain, Marvin L.; Ungaro, Ricardo; Nacionales, Dina C.; Larson, Shawn D.; Sharma, Ashish; Upchurch, Gilburt; Wallet, Shannon M.; Brusko, Todd M.; Loftus, Tyler J.; Mohr, Alicia M.; Maile, Robert; Bacher, Rhonda; Cai, Guoshuai; Kladde, Michael P.; Mathews, Clayton E.; Moldawer, Lyle L.; Brusko, Maigan A.; Efron, Philip A.

Nonselective beta blockade enhances gut microbiome diversity in a rodent model of trauma, hemorrhage, and chronic stress

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY

IF3.7

2024-11-13

PREAI

Munley, Jennifer A.; Kelly, Lauren S.; Park, Gwoncheol; Pons, Erick E.; Apple, Camille G.; Kannan, Kolenkode B.; Bible, Letitia E.; Efron, Philip A.; Nagpal, Ravinder; Mohr, Alicia M.

Examining bile acids in pediatric sepsis - a step in the right direction

PEDIATRIC RESEARCH

IF3.1

2024-11-01

PREAI

Hernandez-Rios, Miguel; Rincon, Jaimar C.; Efron, Philip A.; Larson, Shawn D.

Severe trauma leads to sustained muscle loss, induced frailty, and distinct temporal changes in myokine and chemokine profiles of older patients

SURGERY

IF2.7

2024-11-01

PREAI

Polcz, Valerie E.; Barrios, Evan L.; Cox, Michael C.; Rocha, Ivanna; Liang, Muxuan; Hawkins, Russell B.; Darden, Dijoia; Ungaro, Ricardo; Dirain, Marvin; Mankowski, Robert; Mohr, Alicia M.; Moore, Frederick A.; Moldawer, Lyle L.; Efron, Philip A.; Brakenridge, Scott C.; Loftus, Tyler J.

Surviving septic patients endotyped with a functional assay demonstrate active immune responses

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-10-14

OAAI

Price, Adam D.; Becker, Ellen R.; Barrios, Evan L.; Mazer, Monty B.; McGonagill, Patrick W.; Bergmann, Christian B.; Goodman, Michael D.; Gould, Robert W.; Rao, Mahil; Polcz, Valerie E.; Kucaba, Tamara A.; Walton, Andrew H.; Miles, Sydney; Xu, Julie; Liang, Muxuan; Loftus, Tyler J.; Efron, Philip A.; Remy, Kenneth E.; Brakenridge, Scott C.; Badovinac, Vladimir P.; Griffith, Thomas S.; Moldawer, Lyle L.; Hotchkiss, Richard S.; Caldwell, Charles C.

研究方向