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G

Gabriel Helmlinger

quantitative medicines

25H指数
93论文数
5.3K被引数
收录论文 47
发表时间
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Bayesian Workflow for Minimal PBPK Models: Case Study of Dapagliflozin贝叶斯工作流程在最小PBPK模型中的应用：达格列净案例研究
errCPT-Pharmacometrics & Systems Pharmacology
IF3
err2026-09-15
err0
errOAAI
errAnna Mikhailova; Kirill Peskov; Gabriel Helmlinger; Victor Sokolov
err分享
err收藏
Niraparib PBPK modeling to predict optimal dosage in patients with hepatic impairmentNiraparib PBPK建模以预测肝功能不全患者的最佳剂量
errFrontiers in Pharmacology
IF4.8
err2026-05-11
err0
errOAAI
errAP Anatoly Pokladyuk; VV Veronika Voronova; GH Gabriel Helmlinger; KP Kirill Peskov; YK Yuri Kosinsky
err分享
err收藏
Multiscale physiologically-based model of age-dependent CD4+ T-lymphocyte homeostasis年龄依赖性CD4 T淋巴细胞稳态的多尺度生理模型
errFrontiers in Immunology
IF5.9
err2026-02-05
err0
errOAAI
errVictoria Kulesh; Kirill Peskov; Gabriel Helmlinger; Gennady Bocharov
err分享
err收藏
A Systematic Comparative Analysis of Tumor Size Models Based on Erlotinib Clinical Data in Advanced NSCLC基于厄洛替尼临床数据的晚期NSCLC肿瘤大小模型系统性比较分析
errcpt pharmacometrics systems pharmacology
IF0
err2025-08-11
err0
errOAAI
errAnna Mishina; Kirill Zhudenkov; Gabriel Helmlinger; Kirill Peskov
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Mathematical modeling in autoimmune diseases: from theory to clinical application (vol 15,1371620,2024)
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2025-01-30
err0
errOAAI
errUgolkov, Yaroslav; Nikitich, Antonina; Leon, Cristina; Helmlinger, Gabriel; Peskov, Kirill; Sokolov, Victor; Volkova, Alina
err分享
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Systematic review and quantitative meta-analysis of age-dependent human T-lymphocyte homeostasis年龄依赖性人类T淋巴细胞稳态的系统评价和定量荟萃分析
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2025-01-27
err0
errOAAI
errKulesh, Victoria; Peskov, Kirill; Helmlinger, Gabriel; Bocharov, Gennady
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L-Type amino acid transporter 1-targeting nanoparticles for antisense oligonucleotide delivery to the CNS
errMOLECULAR THERAPY NUCLEIC ACIDS
IF6.1
err2024-12-01
err0
errOAAI
errLim, Yu Na; Ryu, In Soo; Jung, Yeon-Joo; Helmlinger, Gabriel; Kim, Insun; Park, Hye Won; Kang, Hansol; Lee, Jina; Lee, Hyo Jin; Lee, Kang Seon; Jang, Ha-Na; Ha, Dae-In; Park, Junghyung; Won, Jinyoung; Lim, Kyung Seob; Jeon, Chang-Yeop; Cho, Hyun-Jeong; Min, Hyun Su; Ryu, Jin-Hyeob
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err收藏
Mathematical modeling of endogenous and exogenously administered T cell recirculation in mouse and its application to pharmacokinetic studies of cell therapies
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-04-17
err1
errOAAI
errNikitich, Antonina; Helmlinger, Gabriel; Peskov, Kirill; Bocharov, Gennady
err分享
err收藏
Mathematical modeling in autoimmune diseases: from theory to clinical application
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-03-14
err0
errOAAI
errUgolkov, Yaroslav; Nikitich, Antonina; Leon, Cristina; Helmlinger, Gabriel; Peskov, Kirill; Sokolov, Victor; Volkova, Alina
err分享
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An integrative mechanistic model of thymocyte dynamics胸腺细胞动力学的综合机制模型
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-02-26
err1
errOAAI
errKulesh, Victoria; Peskov, Kirill; Helmlinger, Gabriel; Bocharov, Gennady
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A workflow for the joint modeling of longitudinal and event data in the development of therapeutics: Tools, statistical methods, and diagnostics
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2022-02-21
err8
errOAAI
errZhudenkov, Kirill; Gavrilov, Sergey; Sofronova, Alina; Stepanov, Oleg; Kudryashova, Nataliya; Helmlinger, Gabriel; Peskov, Kirill
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cytoTIL15: A novel TIL therapy for melanoma with superior potency and enhanced persistence without IL2 to improve safety & efficacy and expand patient eligibility
errANNALS OF ONCOLOGY
IF65.4
err2021-09-01
err1
errOAAI
errKhattar, M.; Burga, R.; Pedro, K.; Foley, C.; Lajoie, S.; Ocando, A. V.; Tremblay, J.; Thornton, D.; Tam, S.; Nabulsi, F.; Vallaster, C.; Saha, S.; Wilmes, G.; Helmlinger, G.; Tchaicha, J.; Sethi, D.; Ols, M.; Vanasse, G.; Subramanian, S.; ter Meulen, J.
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Evaluation of Combination Strategies for the A2AR Inhibitor AZD4635 Across Tumor Microenvironment Conditions via a Systems Pharmacology Model
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2021-03-02
err12
errOAAI
errVoronova, Veronika; Peskov, Kirill; Kosinsky, Yuri; Helmlinger, Gabriel; Chu, Lulu; Borodovsky, Alexandra; Woessner, Richard; Sachsenmeier, Kris; Shao, Wenlin; Kumar, Rakesh; Pouliot, Gayle; Merchant, Melinda; Kimko, Holly; Mugundu, Ganesh
err分享
err收藏
Longitudinal Tumor Size and Neutrophil-to-Lymphocyte Ratio Are Prognostic Biomarkers for Overall Survival in Patients With Advanced Non-Small Cell Lung Cancer Treated With Durvalumab
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2020-12-21
err19
errOAAI
errGavrilov, Sergey; Zhudenkov, Kirill; Helmlinger, Gabriel; Dunyak, James; Peskov, Kirill; Aksenov, Sergey
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Renal Effects of Dapagliflozin in People with and without Diabetes with Moderate or Severe Renal Dysfunction: Prospective Modeling of an Ongoing Clinical Trial
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2020-10-01
err9
errOAAI
errHallow, K. Melissa; Boulton, David W.; Penland, Robert C.; Helmlinger, Gabriel; Nieves, Emily H.; van Raalte, Daniel H.; Heerspink, Hiddo L.; Greasley, Peter J.
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Quantification of Scheduling Impact on Safety and Efficacy Outcomes of Brain Metastasis Radio- and Immuno-Therapies: A Systematic Review and Meta-Analysis
errFRONTIERS IN ONCOLOGY
IF3.3
err2020-09-02
err8
errOAAI
errVoronova, Veronika; Lebedeva, Svetlana; Sekacheva, Marina; Helmlinger, Gabriel; Peskov, Kirill
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Dose dependence of treatment-related adverse events for immune checkpoint inhibitor therapies: a model-based meta-analysis免疫检查点抑制剂治疗相关不良事件的剂量依赖性: 基于模型的meta分析
errONCOIMMUNOLOGY
IF6.3
err2020-05-21
err30
errOAAI
errShulgin, Boris; Kosinsky, Yuri; Omelchenko, Andrey; Chu, Lulu; Mugundu, Ganesh; Aksenov, Sergey; Pimentel, Rodrigo; DeYulia, Garrett; Kim, Geoffrey; Peskov, Kirill; Helmlinger, Gabriel
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Effect of URAT1 inhibition with verinurad on proximal tubule intracellular lactate: A mathematical modeling analysis and hypothesis for antiproteinuric effect
errFASEB JOURNAL
IF4.2
err2020-04-20
err0
errOAAI
errNieves, Emily; Hallow, Melissa; Greasley, Peter; Helmlinger, Gabriel; Parkinson, Joanna
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Differentiating the Sodium-Glucose Cotransporter 1 Inhibition Capacity of Canagliflozin vs. Dapagliflozin and Empagliflozin Using Quantitative Systems Pharmacology Modeling
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2020-03-06
err31
errOAAI
errSokolov, Victor; Yakovleva, Tatiana; Chu Lulu; Tang Weifeng; Greasley, Peter J.; Johansson, Susanne; Peskov, Kirill; Helmlinger, Gabriel; Boulton, David W.; Penland, Robert C.
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A Physiology-Based Model of rile Acid Distribution and Metabolism Under Healthy Pathologic Conditions in Human Beings在人类健康病理条件下基于生理学的rile酸分布和代谢模型
errCELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
IF7.4
err2020-01-01
err34
errOAAI
errVoronova, Veronika; Sokolov, Victor; Al-Khaifi, Amani; Straniero, Sara; Kumar, Chanchal; Peskov, Kirill; Helmlinger, Gabriel; Rudling, Mats; Angelin, Bo
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研究方向

暂无研究方向
合作学者
合作期刊
J
John J.V. McMurray
H 指数: 231 · 论文数: 2.6K
R
Rakesh K. Jain
H 指数: 200 · 论文数: 1.7K
H
Hiddo J.L. Heerspink
H 指数: 118 · 论文数: 1.1K
H
Helena Edlund
H 指数: 86 · 论文数: 163
V
Volker Vallon
H 指数: 85 · 论文数: 341
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