Hepatocyte-specific mutation establishes retinoid X receptor α as a heterodimeric integrator of multiple physiological processes in the liverMOLECULAR AND CELLULAR BIOLOGYIF2.72023-03-28216OAAI
The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesionsMOLECULAR AND CELLULAR BIOLOGYIF2.72023-03-27159OAAI
Niemann-Pick C1-deficient mice lacking sterol O-acyltransferase 2 have less hepatic cholesterol entrapment and improved liver functionAMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGYIF3.32018-10-018OAAI
ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolismPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAIF9.12018-09-18116OAAI
Normalization of Hepatic Homeostasis in the Npc1nmf164 Mouse Model of Niemann-Pick Type C Disease Treated with the Histone Deacetylase Inhibitor VorinostatJOURNAL OF BIOLOGICAL CHEMISTRYIF3.92017-03-0132OAAI
Hepatic entrapment of esterified cholesterol drives continual expansion of whole body sterol pool in lysosomal acid lipase-deficient miceAMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGYIF3.32014-10-1527OAAI
Histone Deacetylase 9 Represses Cholesterol Efflux and Alternatively Activated Macrophages in Atherosclerosis DevelopmentARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGYIF7.42014-09-01156OAAI
Sustained and selective suppression of intestinal cholesterol synthesis by Ro 48-8071, an inhibitor of 2,3-oxidosqualene:lanosterol cyclase, in the BALB/c mouseBIOCHEMICAL PHARMACOLOGYIF5.62014-04-0114OAAI
A Functional, Genome-wide Evaluation of Liposensitive Yeast Identifies the ARE2 Required for Viability (ARV1) Gene Product as a Major Component of Eukaryotic Fatty Acid ResistanceJOURNAL OF BIOLOGICAL CHEMISTRYIF3.92014-02-0132OAAI
Role of Calcium and EPAC in Norepinephrine-Induced Ghrelin SecretionENDOCRINOLOGYIF3.32014-01-0124OAAI
Characterization of Cholesterol Homeostasis in Telomerase-immortalized Tangier Disease Fibroblasts Reveals Marked Phenotype VariabilityJOURNAL OF BIOLOGICAL CHEMISTRYIF3.92013-12-019OAAI
The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolismJOURNAL OF CLINICAL INVESTIGATIONIF13.62012-12-21115OA
Cyclodextrin mediates rapid changes in lipid balance in Npc1-/- mice without carrying cholesterol through the bloodstreamJOURNAL OF LIPID RESEARCHIF4.12012-11-0163OAAI
Delineation of biochemical, molecular, and physiological changes accompanying bile acid pool size restoration in Cyp7a1-/- mice fed low levels of cholic acidAMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGYIF3.32012-07-1521OAAI
Quantitative role of LAL, NPC2, and NPC1 in lysosomal cholesterol processing defined by genetic and pharmacological manipulationsJOURNAL OF LIPID RESEARCHIF4.12011-04-0174OAAI
Multiple mechanisms limit the accumulation of unesterified cholesterol in the small intestine of mice deficient in both ACAT2 and ABCA1AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGYIF3.32010-11-0129OAAI
Weekly Cyclodextrin Administration Normalizes Cholesterol Metabolism in Nearly Every Organ of the Niemann-Pick Type C1 Mouse and Markedly Prolongs LifePEDIATRIC RESEARCHIF3.12010-10-01157OAAI
Chronic social defeat stress disrupts regulation of lipid synthesisJOURNAL OF LIPID RESEARCHIF4.12010-06-01105OAAI
Cyclodextrin overcomes the transport defect in nearly every organ of NPC1 mice leading to excretion of sequestered cholesterol as bile acidJOURNAL OF LIPID RESEARCHIF4.12010-05-01164OAAI
Liver X Receptor Agonists Augment Human Islet Function through Activation of Anaplerotic Pathways and Glycerolipid/Free Fatty Acid CyclingJOURNAL OF BIOLOGICAL CHEMISTRYIF3.92010-02-0141OAAI
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