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Fernand-Pierre Gendron

Université de Sherbrooke

H指数:27

被引数:1,827

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Structure-based design of macrocyclic peptides to generate functional antibodies against G protein-coupled receptors

基于结构的环肽设计以生成靶向G蛋白偶联受体的功能性抗体

Nature Communications

IF15.7

2025-12-120

OAAI

A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells

IF3.2

2021-05-2517

OAAI

The expression of P2Y6 receptor promotes the quality of mucus in colitic mice

IF4.2

2021-03-2510

OAAI

Structure-activity relationship study of NPP1 inhibitors based on uracil-N1-(methoxy)ethyl-β-phosphate scaffold

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-12-017

PREAI

Reviewing the role of P2Y receptors in specific gastrointestinal cancers

PURINERGIC SIGNALLING

IF2.4

2019-09-0229

OAAI

Highly Selective and Potent Ectonucleotide Pyrophosphatase-1 (NPP1) Inhibitors Based on Uridine 5′-Pα,α-Dithiophosphate Analogues

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2018-04-2227

PREAI

The loss of P2X7 receptor expression leads to increase intestinal glucose transit and hepatic steatosis

SCIENTIFIC REPORTS

IF3.9

2017-10-1019

OAAI

The G protein-coupled P2Y6 pyrimidoceptor increases tumorigenesis potential of epithelial cell in colorectal cancer associated to colitis

CANCER RESEARCH

IF16.6

2017-07-010

PRE

Gata4 is critical to maintain gut barrier function and mucosal integrity following epithelial injury

SCIENTIFIC REPORTS

IF3.9

2016-11-0919

OAAI

The G protein-coupled P2Y6 pyrimidoceptor protects colorectal cancerous epithelial cells from apoptosis: Is this receptor a novel target against colorectal cancer

CANCER RESEARCH

IF16.6

2016-07-150

PRE

Synthesis and structure-activity relationship of uracil nucleotide derivatives towards the identification of human P2Y6 receptor antagonists

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2015-09-0122

PREAI

The acetylome regulators Hdac1 and Hdac2 differently modulate intestinal epithelial cell dependent homeostatic responses in experimental colitis

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

IF3.3

2014-04-0142

PREAI

Shuttling of information between the mucosal and luminal environment drives intestinal homeostasis

IF3

2014-03-1131

PREAI

UDP made a highly promising stable, potent, and selective P2Y6-receptor agonist upon introduction of a boranophosphate moiety

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2012-09-0125

PRE

Association between genetic variants in the HNF4A gene and childhood-onset Crohn's disease

GENES AND IMMUNITY

IF4.5

2012-08-2345

OAAI

P2Y2 receptor expression is regulated by C/EBPβ during inflammation in intestinal epithelial cells

IF4.2

2012-07-1617

OAAI

Nrf2 Silencing Induces Oxidative Stress, Inflammation and Mitochondrial Dysfunctions in the Intestine

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2011-11-010

PREAI

Modification in Oxidative Stress, Inflammation, and Lipoprotein Assembly in Response to Hepatocyte Nuclear Factor 4α Knockdown in Intestinal Epithelial Cells

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2010-12-0155

OAAI

Hepatocyte Nuclear Factor-4α Promotes Gut Neoplasia in Mice and Protects against the Production of Reactive Oxygen Species

CANCER RESEARCH

IF16.6

2010-11-1485

OAAI

HNF4 alpha: A New Susceptibility Gene for Crohn's Disease?

AMERICAN JOURNAL OF GASTROENTEROLOGY

IF7.6

2010-10-010

PRE