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P

Pranav Shah

national institutes of health
H指数:23
被引数:1,483

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Novel 5-Phenylmorphans as Opioid Receptor Antagonists: Synthesis, Structure-Activity Relationship, Biological Evaluation and Computational Modeling

新型5-苯基吗啡烷作为阿片受体拮抗剂：合成、构效关系、生物评价和计算建模

Molecules
IF4.6
2026-10-020
OA
Zahra Hasanpour; Dan Luo; Thomas E. Prisinzano; Pranav Shah; Dana E. Selley; James C. Gillespie; Laurel A. Grisanti; Carmine Talarico; Davide Graziani; Xin Xu; Andrea R. Beccari; Kun-Eek Kil; Sung Won Kim; Arthur E. Jacobson; Kenner C. Rice; Agnieszka Sulima
Structure–Activity Relationship Studies toward the Optimization of First-In-Class Selective Small Molecule Agonists of the GPCR Relaxin/Insulin-like Family Peptide Receptor 2

结构-活性关系研究以优化首创新药选择性小分子激动剂，针对GPCR松弛素/胰岛素样家族肽受体2

Journal of Medicinal Chemistry
IF6.8
2026-02-190
PRE
Kenneth J. Wilson; Maria Esteban-Lopez; Courtney Myhr; Wenjuan Ye; Curtis E. Moore; Noel Southall; Xin Hu; Abhijeet Kapoor; Konstantinos Afratis; Christopher A. LeClair; Samuel A. Kotler; Pranav Shah; Elias Carvalho Padilha; Yuhong Fang; David Calabrese; Emmett R. George; Amy Wang; Xin Xu; Elena Barnaeva; Marc Ferrer; Mark Henderson; Irina Agoulnik; Alexander I. Agoulnik; Juan J. Marugan
IRAK1/4/pan-FLT3 Kinase Inhibitors with Reduced hERG Block as Treatments for Acute Myeloid Leukemia

IRAK1/4/pan-FLT3激酶抑制剂，具有降低的hERG阻断作用，作为急性髓系白血病的治疗方法

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2025-04-290
PRE
Hoyt, SB; Finocchio, CJ; Croll, E; Tawa, GJ; Zhang, ML; Wang, JG; Li, HX; Ma, L; Li, KK; Zhang, XH; Xu, X; Shah, P; Fang, YH; Bolanos, LC; Gracia-Maldonado, G; Kolt, A; Robinson, C; Free, J; Edmondson, EF; Difilippantonio, S; Jones, LM; Culver-Cochran, AE; Rosenbaum, JS; Starczynowski, DT; Thomas, CJ
Discovery of IRAK1/4/pan-FLT3 Kinase Inhibitors as Treatments for Acute Myeloid Leukemia
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2024-10-231
OAAI
Hoyt, Scott B.; Finocchio, Chris J.; Croll, Elizabeth; Tawa, Gregory J.; Li, Huixu; Ma, Li; Li, Kaikai; Liu, Li; Li, Ranran; Zhang, Xiaohu; Wilson, Kelli; Xu, Xin; Shah, Pranav; Williams, Jordan; Fang, Yuhong; Bolanos, Lyndsey C.; Gracia-Maldonado, Gabriel; Kolt, Amal; Robinson, Christina; Free, Jessica; Edmondson, Elijah F.; Difilippantonio, Simone; Jones, LaQuita M.; Culver-Cochran, Ashley E.; Rosenbaum, Jan S.; Starczynowski, Daniel T.; Thomas, Craig J.
In vitro and in vivo pharmacokinetic characterization, chiral conversion and PBPK scaling towards human PK simulation of S-MRI-1867, a drug candidate for Hermansky-Pudlak syndrome pulmonary fibrosis

Hermansky-pudlak综合征肺纤维化的候选药物S-MRI-1867的体外和体内药代动力学表征，手性转化和PBPK缩放

BIOMEDICINE & PHARMACOTHERAPY
IF7.5
2023-12-011
OAAI
Padilha, Elias C.; Yang, Mengbi; Shah, Pranav; Wang, Amy Q.; Duan, Jianmin; Park, Joshua K.; Zawatsky, Charles N.; Malicdan, May Christine V.; Kunos, George; Iyer, Malliga R.; Gaucher, Genevieve; Ravenelle, Francois; Cinar, Resat; Xu, Xin
Prevalence and Causes of Diagnostic Errors in Hospitalized Patients Under Investigation for COVID-19
JOURNAL OF GENERAL INTERNAL MEDICINE
IF4.2
2023-03-237
OAAI
Auerbach, Andrew D.; Astik, Gopi J.; O'Leary, Kevin J.; Barish, Peter N.; Kantor, Molly A.; Raffel, Katie R.; Ranji, Sumant R.; Mueller, Stephanie K.; Burney, Sharran N.; Galinsky, Janice; Gershanik, Esteban F.; Goyal, Abhishek; Chitneni, Pooja R.; Rastegar, Sarah; Esmaili, Armond M.; Fenton, Cynthia; Virapongse, Anunta; Ngov, Li-Kheng; Burden, Marisha; Keniston, Angela; Patel, Hemali; Gupta, Ashwin B.; Rohde, Jeff; Marr, Ruby; Greysen, S. Ryan; Fang, Michele; Shah, Pranav; Mao, Frances; Kaiksow, Farah; Sterken, David; Choi, Justin J.; Contractor, Jigar; Karwa, Abhishek; Chia, David; Lee, Tiffany; Hubbard, Colin C.; Maselli, Judith; Dalal, Anuj K.; Schnipper, Jeffrey L.
Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2022-06-138
OA
Frankowski, Kevin J.; Patnaik, Samarjit; Wang, Chen; Southall, Noel; Dutta, Dipannita; De, Soumitta; Li, Dandan; Dextras, Christopher; Lin, Yi-Han; Bryant-Connah, Marthe; Davis, Danielle; Wang, Feijun; Wachsmuth, Leah M.; Shah, Pranav; Williams, Jordan; Kabir, Md; Zhu, Edward; Baljinnyam, Bolormaa; Wang, Amy; Xu, Xin; Norton, John; Ferrer, Marc; Titus, Steve; Simeonov, Anton; Zheng, Wei; Griner, Lesley A. Mathews; Jadhav, Ajit; Aube, Jeffrey; Henderson, Mark J.; Rudloff, Udo; Schoenen, Frank J.; Huang, Sui; Marugan, Juan J.
Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites
SCIENTIFIC REPORTS
IF3.9
2021-01-2220
OAAI
Dorjsuren, Dorjbal; Eastman, Richard T.; Wicht, Kathryn J.; Jansen, Daniel; Talley, Daniel C.; Sigmon, Benjamin A.; Zakharov, Alexey V.; Roncal, Norma; Girvin, Andrew T.; Antonova-Koch, Yevgeniya; Will, Paul M.; Shah, Pranav; Sun, Hongmao; Klumpp-Thomas, Carleen; Mok, Sachel; Yeo, Tomas; Meister, Stephan; Marugan, Juan Jose; Ross, Leila S.; Xu, Xin; Maloney, David J.; Jadhav, Ajit; Mott, Bryan T.; Sciotti, Richard J.; Winzeler, Elizabeth A.; Waters, Norman C.; Campbell, Robert F.; Huang, Wenwei; Simeonov, Anton; Fidock, David A.

研究方向

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X
Xin Xu
H 指数:41论文数:210被引数:6,789
A
Anton Simeonov
H 指数:85论文数:705被引数:2.5万
A
Ajit Jadhav
H 指数:67论文数:317被引数:1.9万
M
Mark J. Henderson
H 指数:28论文数:130被引数:2,560
E
Elias Carvalho Padilha
H 指数:14论文数:43被引数:1,049
A
Amy Q. Wang
H 指数:21论文数:51被引数:2,588
R
Ruili Huang
H 指数:58论文数:320被引数:1.3万
M
Menghang Xia
H 指数:57论文数:336被引数:1.4万
Y
Yuhong Fang
H 指数:15论文数:83被引数:2,451
V
Vishal B. Siramshetty
H 指数:16论文数:42被引数:1,395