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Xiaohui Zheng

Wenzhou Medical University

H指数:22

被引数:1,847

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Lespedeza bicolor root extract ameliorates LPS-induced acute lung injury through p38 MAPK/NF-κB pathway

胡枝子根提取物通过p38 MAPK/NF-κB通路改善LPS诱导的急性肺损伤

Microbial Pathogenesis

IF3.5

2026-06-010

PRE

Discovery and Structural Optimization of Novel 2-Aminopyrimidine Derivatives as Potent and Selective IKKβ Inhibitors for the Treatment of Colorectal Cancer

新型2-氨基嘧啶衍生物的发现与结构优化：作为强效且选择性IKKβ抑制剂的结直肠癌治疗药物

Journal of Medicinal Chemistry

IF6.8

2025-12-020

PRE

Discovery of Novel 2,4,5-Trisubstituted Pyrimidine Derivatives as Potent and Selective FGFR Inhibitors against Gatekeeper Mutants for the Treatment of NSCLC

新型2,4,5-三取代嘧啶衍生物作为针对门控突变体的强效且选择性FGFR抑制剂的发现，用于NSCLC的治疗

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-03-030

PRE

Design, synthesis, and biological evaluation of Flavokavain B derivatives as potent TRF2 inhibitors for the treatment of Osteosarcoma

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2025-03-010

PRE

Discovery of a selective TRF2 inhibitor FKB04 induced telomere shortening and senescence in liver cancer cells (vol 45, pg 1276, 2024)

ACTA PHARMACOLOGICA SINICA

IF8.4

2024-08-281

OA

H2O2 promotes photodynamic efficacy of TMPyP4 against ovarian cancer in vitro by downregulating HIF-1α expression

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2024-08-011

OAAI

Discovery of a selective TRF2 inhibitor FKB04 induced telomere shortening and senescence in liver cancer cells

ACTA PHARMACOLOGICA SINICA

IF8.4

2024-03-042

PRE

cyy-287, a novel pyrimidine-2,4-diamine derivative, inhibits tumor growth of EGFR-driven non-small cell lung cancer via the ERK pathway

ACTA BIOCHIMICA ET BIOPHYSICA SINICA

IF3.4

2022-10-133

OAAI

A chalcone-syringaldehyde hybrid inhibits triple-negative breast cancer cell proliferation and migration by inhibiting CKAP2-mediated FAK and STAT3 phosphorylation

IF8.3

2022-07-0114

OAAI

G-quadruplex stabilizer Tetra-Pt(bpy) disrupts telomere maintenance and impairs FAK-mediated migration of telomerase-positive cells

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2022-07-018

PRE

The novel FGFR inhibitor F1-7 induces DNA damage and cell death in colon cells

BRITISH JOURNAL OF CANCER

IF6.8

2022-06-175

OA

Narciclasine suppresses esophageal cancer cell proliferation and migration by inhibiting the FAK signaling pathway

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2022-04-0111

PRE

Discovery of Potent and Orally Bioavailable Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for the Treatment of Osteosarcoma

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-03-039

PRE

mTORC1 Promotes ARID1A Degradation and Oncogenic Chromatin Remodeling in Hepatocellular Carcinoma

CANCER RESEARCH

IF16.6

2021-08-2424

OA

The different biological effects of TMPyP4 and cisplatin in the inflammatory microenvironment of osteosarcoma are attributed to G-quadruplex

CELL PROLIFERATION

IF5.6

2021-07-2313

OAAI

Piperlongumine inhibits migration and proliferation of castration-resistant prostate cancer cells via triggering persistent DNA damage

BMC COMPLEMENTARY MEDICINE AND THERAPIES

IF3.4

2021-07-0622

OAAI

Design, synthesis, and biological evaluation of indazole derivatives as selective and potent FGFR4 inhibitors for the treatment of FGF19-driven hepatocellular cancer

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-03-0114

PREAI

Synthesis and biological evaluation of novel N-substituted benzamides as anti-migration agents for treatment of osteosarcoma

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-03-013

PREAI

miR-196b-5p-mediated downregulation of FAS promotes NSCLC progression by activating IL6-STAT3 signaling

CELL DEATH & DISEASE

IF9.6

2020-09-2230

OAAI

Preparation and Chemical Protective Clothing Application of PVDF Based Sodium Sulfonate Membrane

IF3.6

2020-08-1713

OAAI