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收藏分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Current Approaches for Predicting Human PK for Small Molecule Development Candidates: Findings from the IQ Human PK Prediction Working Group Survey
Petersson, Carl; Zhou, Xin; Berghausen, Joerg; Cebrian, David; Davies, Michael; DeMent, Kevin; Eddershaw, Peter; Riedmaier, Arian Emami; Leblanc, Alix F.; Manveski, Nenad; Marathe, Punit; Mavroudis, Panteleimon D.; McDougall, Robin; Parrott, Neil; Reichel, Andreas; Rotter, Charles; Tess, David; Volak, Laurie P.; Xiao, Guangqing; Yang, Zheng; Baker, James 分享 收藏 Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain-a Game Changing Parameter for CNS Drug Discovery and Development未结合的脑-血浆分配系数，Kp，uu，脑-CNS药物发现和开发的游戏改变参数Loryan, Irena; Reichel, Andreas; Feng, Bo; Bundgaard, Christoffer; Shaffer, Christopher; Kalvass, Cory; Bednarczyk, Dallas; Morrison, Denise; Lesuisse, Dominique; Hoppe, Edmund; Terstappen, Georg C.; Fischer, Holger; Di, Li; Colclough, Nicola; Summerfield, Scott; Buckley, Stephen T.; Maurer, Tristan S.; Friden, Markus 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Favorable outcome of experimental islet xenotransplantation without immunosuppression in a nonhuman primate model of diabetes在非人灵长类动物糖尿病模型中无免疫抑制的实验性胰岛异种移植的良好结果Ludwig, Barbara; Ludwig, Stefan; Steffen, Anja; Knauf, Yvonne; Zimerman, Baruch; Heinke, Sophie; Lehmann, Susann; Schubert, Undine; Schmid, Janine; Bleyer, Martina; Schoenmann, Uwe; Colton, Clark K.; Bonifacio, Ezio; Solimena, Michele; Reichel, Andreas; Schally, Andrew V.; Rotem, Avi; Barkai, Uriel; Grinberg-Rashi, Helena; Kaup, Franz-Josef; Avni, Yuval; Jones, Peter; Bornstein, Stefan R. 分享 收藏 An international multicenter study comparing EUS-guided pancreatic duct drainage with enteroscopy-assisted endoscopic retrograde pancreatography after Whipple surgeryChen, Yen-I; Levy, Michael J.; Moreels, Tom G.; Hajijeva, Gulara; Will, Uwe; Artifon, Everson L.; Hara, Kazuo; Kitano, Masayuki; Topazian, Mark; Abu Dayyeh, Barham; Reichel, Andreas; Vilela, Tiago; Ngamruengphong, Saowanee; Haito-Chavez, Yamile; Bukhari, Majidah; Okolo, Patrick, III; Kumbhari, Vivek; Ismail, Amr; Khashab, Mouen A. 分享 收藏 分享 收藏 分享 收藏 An International Multicenter Study Comparing EUS-Guided Pancreatic Duct Drainage With Enteroscopy-Assisted Endoscopic Retrograde Pancreatography Following Whipple SurgeryChen, Yen-I.; Levy, Michael J.; Moreels, Tom G.; Hajiyeva, Gulara; Will, Uwe; Artifon, Everson L.; Hara, Kazuo; Kitano, Masayuki; Topazian, Mark; Abu Dayyeh, Barham K.; Reichel, Andreas; Vilela, Tiago; Ngamruengphong, Saowanee; Chavez, Yamile Haito; Bukhari, Majidah; Okolo, Patrick I.; Ismail, Amr; Kumbhari, Vivek; El Zein, Mohamad H.; Khashab, Mouen A. 分享 收藏 Incidence of Bleeding in 8172 Percutaneous Ultrasound-Guided Intraabdominal Diagnostic and Therapeutic Interventions - Results of the Prospective Multicenter DEGUM Interventional Ultrasound Study (PIUS Study)Strobel, D.; Bernatik, T.; Blank, W.; Will, U.; Reichel, A.; Wuestner, M.; Keim, V.; Schacherer, D.; Barreiros, A. P.; Kunze, G.; Nuernberg, D.; Ignee, A.; Burmester, E.; Bunk, A. A.; Friedrich-Rust, M.; Froehlich, E.; Schuler, A.; Jenssen, C.; Bohle, W.; Mauch, M.; Dirks, K.; Kaemmer, J.; Pachmann, C.; Stock, J.; Hocke, M.; Kendel, A.; Schmidt, C.; Jakobeit, C.; Kinkel, H.; Heinz, W.; Huebner, G.; Pichler, M.; Mueller, T. 分享 收藏 Transplantation of human islets without immunosuppressionLudwig, Barbara; Reichel, Andreas; Steffen, Anja; Zimerman, Baruch; Schally, Andrew V.; Block, Norman L.; Colton, Clark K.; Ludwig, Stefan; Kersting, Stephan; Bonifacio, Ezio; Solimena, Michele; Gendler, Zohar; Rotem, Avi; Barkai, Uriel; Bornstein, Stefan R. 分享 收藏 The Lab Oddity Prevails: Discovery of Pan-CDK Inhibitor (R)-S-Cyclopropyl-S-(4-{[4-{[(1R,2R)-2-hydroxy-1-methylpropyl]oxy}-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)sulfoximide (BAY1000394) for the Treatment of Cancer实验室的奇怪之处在于: 发现了泛CDK抑制剂 (R)-S-环丙基-S-(4-{[(1R，2R)-2-羟基-1-甲基丙基] 氧基}-5-(三氟甲基) pyrimidin-2-yl] 氨基} 苯基磺酰亚胺 (BAY1000394) 用于治疗癌症Luecking, Ulrich; Jautelat, Rolf; Krueger, Martin; Brumby, Thomas; Lienau, Philip; Schaefer, Martina; Briem, Hans; Schulze, Julia; Hillisch, Alexander; Reichel, Andreas; Wengner, Antje Margret; Siemeister, Gerhard 分享 收藏 Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonistLudwig, Barbara; Rotem, Avi; Schmid, Janine; Weir, Gordon C.; Colton, Clark K.; Brendel, Mathias D.; Neufeld, Tova; Block, Norman L.; Yavriyants, Karina; Steffen, Anja; Ludwig, Stefan; Chavakis, Triantafyllos; Reichel, Andreas; Azarov, Dimitri; Zimermann, Baruch; Maimon, Shiri; Balyura, Mariya; Rozenshtein, Tania; Shabtay, Noa; Vardi, Pnina; Bloch, Konstantin; de Vos, Paul; Schally, Andrew V.; Bornstein, Stefan R.; Barkai, Uriel 分享 收藏 
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