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Daniel Pettersen

early clinical development, cardiovascular, renal and metabolism, biopharmaceuticals r&d, astrazeneca, stockholm, sweden
H指数:21
被引数:1,385
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Re-PERFUSE: Phase 1b study of AZD3427, a novel relaxin receptor agonist, on renal perfusion in HFrEF patients

Re-PERFUSE:AZD3427(一种新型松弛素受体激动剂)对HFrEF患者肾脏灌注的1b期研究

2025-09-040
OAAI
Preclinical Evaluation and First-In-Human Phase 1 Trial of AZD0186, a Novel, Oral Small Molecule Glucagon-Like Peptide-1 Receptor Agonist

AZD0186的临床前评估与首次人体I期试验,AZD0186是一种新型口服小分子胰高血糖素样肽-1受体激动剂

2025-08-280
OAAI
A novel long-acting relaxin-2 fusion, AZD3427, improves cardiac performance in non-human primates with cardiac dysfunction

一种新型的长效松弛素-2融合蛋白AZD3427能够改善心脏功能不全的非人灵长类动物的心脏功能。

2025-03-031
PRE
Novel Relaxin Receptor RXFP1 Agonist AZD3427 in the Treatment of Heart Failure: A Phase 1a/b, First-in-Human, Randomized, Single-Blind, Placebo-Controlled Study
2024-08-062
PRE
Discovery and Early Clinical Development of an Inhibitor of 5-Lipoxygenase Activating Protein (AZD5718) for Treatment of Coronary Artery Disease
2019-03-1430
PREAI
Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X (sPLA2-X) Inhibitors
2018-06-239
OAAI
Design of Selective sPLA2-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid
2018-06-235
OAAI
Discovery of AZD2716: A Novel Secreted Phospholipase A2 (sPLA2) Inhibitor for the Treatment of Coronary Artery Disease
2016-08-2232
OAAI
Discovery of the Fibrinolysis Inhibitor AZD6564, Acting via Interference of a Protein-Protein Interaction
2014-02-2140
OA
An easy entry to optically active α-amino phosphonic acid derivatives using phase-transfer catalysis (PTC)
2008-01-0146
PRE
Organocatalytic asymmetric Mannich reactions with N-boc and N-cbz protected α-amido Sulfones (Boc: tert-butoxycarbonyl, Cbz: benzyloxycarbonyl)
2007-09-25119
PREAI
Organocatalytic enantioselective decarboxylative addition of malonic half thioesters to imines
2007-05-18117
PREAI
Phase transfer catalyzed enantioselective strecker reactions of α-amido sulfones with cyanohydrins
2006-11-2181
PRE
Phase-transfer-catalyzed enantioselective Mannich reaction of malonates with α-amido sulfones
2006-10-1276
PREAI
Direct access to enantiomerically enriched α-amino phosphonic acid derivatives by organocatalytic asymmetric hydrophosphonylation of imines
2006-07-08151
PRE
Phase-transfer-catalyzed asymmetric aza-Henry reaction using N-carbamoyl imines generated in situ from α-amido sulfones
2005-12-08185
PREAI