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Jenny Sandmark

AstraZeneca
H指数:13
被引数:489
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Design of Bicyclic Peptide Tandems Mimicking the Homodimeric GDF15 Protein to Inhibit GDF15–GFRaL–RET Complex Cell Signaling

双环肽串联的设计:模拟同源二聚体GDF15蛋白以抑制GDF15–GFRaL–RET复合物细胞信号传导

2025-10-090
PRE
Selective and Bioavailable HDAC6 2-(Difluoromethyl)-1,3,4-oxadiazole Substrate Inhibitors and Modeling of Their Bioactivation Mechanism
2023-10-0512
PRE
Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function
2020-04-0110
OAAI
Structural analysis identifies an escape route from the adverse lipogenic effects of liver X receptor ligands
2019-11-2221
OAAI
Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain
2019-07-0521
OAAI
Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X (sPLA2-X) Inhibitors
2018-06-239
OAAI
Design of Selective sPLA2-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid
2018-06-235
OAAI
Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling
2018-04-0125
OAAI
Discovery of AZD2716: A Novel Secreted Phospholipase A2 (sPLA2) Inhibitor for the Treatment of Coronary Artery Disease
2016-08-2232
OAAI