Jinqiang Hou - Publications, H-index & Citations

Jinqiang Hou

Lakehead University

24H指数

64论文数

1.6K被引数

收录论文 39

发表时间

Cancer Cells in Sleep Mode: Wake Them to Eliminate or Keep Them Asleep Forever?

CELLS

IF5.2

2024-12-06

OAAI

Liu, Wenjie; Kovacs, Antal H.; Hou, Jinqiang

Several birds with one stone: exploring the potential of AI methods for multi-target drug design

MOLECULAR DIVERSITY

IF3.8

2024-11-24

PREAI

Mukaidaisi, Muhetaer; Ahmed, Madiha; Grantham, Karl; Al-Jumaily, Aws; Dedhar, Shoukat; Organ, Michael; Tchagang, Alain; Hou, Jinqiang; Ahmed, Syed Ejaz; Dividino, Renata; Li, Yifeng

Design, Synthesis, and Preclinical Evaluation of a High-Affinity 18F-Labeled Radioligand for Myocardial Growth Hormone Secretagogue Receptor Before and After Myocardial Infarction

JOURNAL OF NUCLEAR MEDICINE

IF9.1

2024-09-12

PREAI

Sullivan, Rebecca; Hou, Jinqiang; Yu, Lihai; Wilk, Benjamin; Sykes, Jane; Biernaski, Heather; Butler, John; Kovacs, Michael; Hicks, Justin; Thiessen, Jonathan D.; Dharmakumar, Rohan; Prato, Frank S.; Wisenberg, Gerald; Luyt, Leonard G.; Dhanvantari, Savita

Lysophosphatidic Acid Receptor 1 (LPA1) Antagonists as Potential Migrastatics for Triple Negative Breast Cancer 溶血磷脂酸受体1 (LPA1) 拮抗剂可作为三阴性乳腺癌的潜在抗癌药

CHEMMEDCHEM

IF3.4

2024-05-29

PREAI

Liu, Wenjie; Mousa, Amr A. K.; Hopkins, Austin M.; Wu, Yin Fang; Thu, Kelsie L.; Campbell, Michael; Lees, Simon J.; Ramachandran, Rithwik; Hou, Jinqiang

Selective targeting of Aurora kinase B over A: Uncovering the structural basis for inhibitor specificity through molecular dynamics simulations

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2023-11-01

PREAI

Zhao, Dong; Kovacs, Antal H.; Campbell, Michael; Floriano, Wely; Hou, Jinqiang

Bioinformatic assay reveal the potential mechanism of Guizhi-Shaoyao-Zhimu decoction against rheumatoid arthritis and mild-to-moderate COVID-19

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

IF4.8

2023-08-01

OAAI

Xu, Yongyu; Huang, Zebin; Wu, Guangping; Jin, Fujun; Lin, Shuojia; Zhang, Chuang; Zheng, Jie; Liu, Wenjie; Hou, Jinqiang; Lu, Yu-Jing

A Cytoplasm-Specific Fluorescent Ligand for Selective Imaging of RNA G-Quadruplexes in Live Cancer Cells

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2023-05-02

OAAI

Zheng, Bo-Xin; Long, Wei; She, Meng-Ting; Wang, Yakun; Zhao, Dong; Yu, Jie; Siu-Lun Leung, Alan; Hin Chan, Ka; Hou, Jinqiang; Lu, Yu-Jing; Wong, Wing-Leung

Aurora B Inhibitors as Cancer Therapeutics Aurora B抑制剂作为癌症治疗药物

MOLECULES

IF4.6

2023-04-11

OAAI

Kovacs, Antal H.; Zhao, Dong; Hou, Jinqiang

A red fluorescent small-molecule for visualization of higher-order cyclic dimeric guanosine monophosphate (c-di-GMP) structure in live bacterial cells and real-time monitoring of biofilm formation on biotic and abiotic surfaces 一种红色荧光小分子，用于可视化活细菌细胞中的高级环状二聚鸟苷单磷酸 (c-di-gmp) 结构，并实时监测生物和非生物表面上的生物膜形成

SENSORS AND ACTUATORS B-CHEMICAL

IF7.7

2023-02-01

OAAI

Zhang, Yi-Han; Huang, Xuan-He; Wong, Wing-Leung; Luo, Jun-Ren; Guo, Xiao-Chun; Liu, Wenjie; Hou, Jinqiang; She, Meng-Ting; Jiang, Wen-Hao; Sun, Ning; Lu, Yu-Jing

Can machine learning 'transform' peptides/peptidomimetics into small molecules? A case study with ghrelin receptor ligands

MOLECULAR DIVERSITY

IF3.8

2022-11-04

PREAI

Liu, Wenjie; Hopkins, Austin M.; Yan, Peizhi; Du, Shan; Luyt, Leonard G.; Li, Yifeng; Hou, Jinqiang

Rational design of small-molecules to recognize G-quadruplexes of c-MYC promoter and telomere and the evaluation of their in vivo antitumor activity against breast cancer

NUCLEIC ACIDS RESEARCH

IF13.1

2022-02-15

OAAI

Long, Wei; Bo-Xin Zheng; Li, Ying; Xuan-He Huang; Dan-Min Lin; Cui-Cui Chen; Jin-Qiang Hou; Tian-Miao Ou; Wing-Leung Wong; Zhang, Kun; Yu-Jing Lu

Synthesis and Anti-Influenza Virus Effects of Novel Substituted Polycyclic Pyridone Derivatives Modified from Baloxavir

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-09-22

PREAI

Tang, Lin; Yan, Haiyan; Wu, Weibin; Chen, Dawei; Gao, Zhenxiong; Hou, Jinqiang; Zhang, Cunlong; Jiang, Yuyang

Structural modification of nonspecific thiazole orange for ligand-DNA interaction study: Understanding the ligand recognition selectivity towards G4-DNA over duplex-DNA

JOURNAL OF LUMINESCENCE

IF3.6

2020-10-01

OAAI

Zhu, Yiwen; Hou, Jinqiang; Huang, Xuan-He; Zhong, Dong-Xiao; Long, Wei; Liu, Wenjie; Lu, Yu-Jing; Zhang, Kun; Wong, Wing-Leung

Single Amino Acid Replacement in G-7039 Leads to a 70-fold Increase in Binding toward GHS-R1a G-7039中的单个氨基酸替换导致与GHS-R1a的结合增加70倍

CHEMMEDCHEM

IF3.4

2019-09-30

PREAI

Lalonde, Tyler; Fowkes, Milan M.; Hou, Jinqiang; Thibeault, Pierre E.; Milne, Mark; Dhanvantari, Savita; Ramachandran, Rithwik; Luyt, Leonard G.

A series of modified thiazole orange dye as the highly fluorescent G-quadruplex DNA binders: The study of electronic effects of the substituent on 1-methylquinolinium moiety

JOURNAL OF LUMINESCENCE

IF3.6

2019-01-01

PREAI

Li, Dongli; Long, Wei; Hou, Jinqiang; Deng, Qiang; Guo, Qi; Wong, Wing-Leung; Lu, Yu-Jing; Zhang, Kun

Boosting the turn-on fluorescent signaling ability of thiazole orange dyes: The effectiveness of structural modification site and its unusual interaction behavior with nucleic acids

DYES AND PIGMENTS

IF4.2

2018-12-01

PREAI

Long, Wei; Lu, Yu-Jing; Zhang, Kun; Huang, Xuan-He; Hou, Jin-Qiang; Cai, Sen-Yuan; Li, Ying; Du, Xian; Luyt, Leonard G.; Wong, Wing-Leung; Chow, Cheuk-Fai

Drosophila melanogaster as a function-based high-throughput screening model for antinephrolithiasis agents in kidney stone patients

DISEASE MODELS & MECHANISMS

IF3.3

2018-11-16

OAAI

Ali, Sohrab N.; Dayarathna, Thamara K.; Ali, Aymon N.; Osumah, Tijani; Ahmed, Mohamed; Cooper, Tyler T.; Power, Nicholas E.; Zhang, Dongxing; Kim, Dajung; Kim, Rachel; St Amant, Andre; Hou, Jinqiang; Tailly, Thomas; Yang, Jun; Luyt, Len; Spagnuolo, Paul A.; Burton, Jeremy P.; Razvi, Hassan; Leong, Hon S.

A propeller-like small molecule as a novel G-quadruplex DNA binder: The study of fluorescent sensing property and preferential interactions with human telo21 structure

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2018-10-03

OAAI

Sun, Ning; Li, Dongli; Hou, Jinqiang; Long, Wei; Guo, Qi; Lu, Yujing; Zhang, Kun; Yuan, Wenchang; Wong, Wing-Leung

Development of Candidates for Positron Emission Tomography (PET) Imaging of Ghrelin Receptor in Disease: Design, Synthesis, and Evaluation of Fluorine-Bearing Quinazolinone Derivatives

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2018-01-30

PREAI

Hou, Jinqiang; Kovacs, Michael S.; Dhanvantari, Savita; Luyt, Leonard G.

The interaction of a structural flexible small molecule with nucleic acid structures: Investigation of the origin of fluorescence signal discrimination in sensing and the utilization in live cell imaging

SENSORS AND ACTUATORS B-CHEMICAL

IF7.7

2017-10-01

PREAI

Sun, Ning; Wang, Cong; Xu, Miao-Han; Lu, Yu-Jing; Zheng, Yuan-Yuan; Yan, Yan; Guo, Xiao-Lu; Hou, Jinqiang; Zhang, Kun; Luyt, Leonard G.; Wong, Wing-Leung; Chow, Cheuk-Fai

研究方向