Olivier Lorthioir

astrazeneca

H指数:11

被引数:824

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A unified platform for the rapid assembly of glutarimides for Cereblon E3 ligase modulatory drugs

一个用于快速组装戊二酰亚胺的统一平台，用于Cereblon E3连接酶调节药物

Nature Communications

IF15.7

2026-06-210

Building bridges from flatland: synthetic approaches and applications of 2-aza- and 2-oxa-bicyclo[2.1.1]hexanes

从平面构建桥梁：2-氮杂-和2-氧杂双环[2.1.1]己烷的合成方法与应用

Org. Biomol. Chem.

IF2.7

2025-08-170

PRE

Optimization of Potent, Efficacious, Selective and Blood-Brain Barrier Penetrating Inhibitors Targeting EGFR Exon20 Insertion Mutations

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-09-280

PRE

Thomson, Clare; Braybrooke, Erin; Colclough, Nicola; Davies, Nichola L.; Floc'h, Nicolas; Greenwood, Ryan; Guerot, Carine; Hargreaves, David; Johnstrom, Peter; Khurana, Puneet; Kostomiris, Demetrios H.; Li, Songlei; Lister, Andrew; Lorthioir, Olivier; Martin, Scott; Mccoull, William; Mclean, Neville J.; Mcwilliams, Lisa; Orme, Jonathan P.; Packer, Martin J.; Pearson, Stuart; Swaih, Aisha M.; Tentarelli, Sharon; Tucker, Michael J.; Ward, Richard A.; Wilkinson, Stephen; Winlow, Poppy; Wood, Isabel L.

Merging nucleophilic phosphine catalysis and photocatalysis for the rapid assembly of 2-oxabicyclo-[2.1.1]hexane scaffolds from feedstock allyl alcohols

CHEMICAL SCIENCE

IF7.4

2024-01-010

OAAI

Virtual Screening in the Cloud Identifies Potent and Selective ROS1 Kinase Inhibitors

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2022-08-039

PRE

Potent and Selective Inhibitors of the Epidermal Growth Factor Receptor to Overcome C797S-Mediated Resistance

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-09-0721

PRE

Finlay, M. Raymond, V; Barton, Peter; Bickerton, Sue; Bista, Michal; Colclough, Nicola; Cross, Darren A. E.; Evans, Laura; Floc'h, Nicolas; Gregson, Clare; Guerot, Carine M.; Hargreaves, David; Kang, Xiaoming; Lenz, Eva M.; Li, Xu; Liu, Yi; Lorthioir, Olivier; Martin, Matthew J.; McKerrecher, Darren; McWhirter, Claire; O'Neill, Daniel; Orme, Jonathan P.; Mosallanejad, Arash; Rahi, Amar; Smith, Paul D.; Talbot, Verity; Ward, Richard A.; Wrigley, Gail; Wylot, Marta; Xue, Lin; Yao, Tieguang; Ye, Yang; Zhao, Xiliang

5-HT7 Receptor Antagonists with an Unprecedented Selectivity Profile

CHEMMEDCHEM

IF3.4

2018-03-303

PREAI

Single bead characterization using analytical constructs: Application to quality control of libraries

ANALYTICAL CHEMISTRY

IF6.7

2001-01-2726

PREAI

Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein

JOURNAL OF BIOLOGICAL CHEMISTRY