Harri Härmä - Publications, H-index & Citations

Harri Härmä

University of Turku

29H指数

126论文数

3.2K被引数

收录论文 77

发表时间

Label-free technique for universal and sequence independent detection of oligonucleotides and nuclease activity 用于寡核苷酸和核酸酶活性通用且序列无关检测的无标记技术

NUCLEIC ACIDS RESEARCH

IF13.1

2025-09-23

PREAI

Gooran, Negin; Borsa, Baris A.; Hernandez, Frank J.; Harma, Harri; Kopra, Kari

ADP-ribosyltransferase-based biocatalysis of nonhydrolyzable NAD plus analogs

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2025-01-01

OAAI

Sakari, Moona; Bhadane, Rajendra; Kumar, Sujit; Azevedo, Rita; Malakoutikhah, Morteza; Masoumi, Ahmadreza; Littler, Dene R.; Harma, Harri; Kopra, Kari; Pulliainen, Arto T.

Beyond KRAS(G12C): Biochemical and Computational Characterization of Sotorasib and Adagrasib Binding Specificity and the Critical Role of H95 and Y96 超越KRAS(G12C): Sotorasib和Adagrasib结合特异性的生化和计算表征以及H95和Y96的关键作用

ACS CHEMICAL BIOLOGY

IF3.8

2024-09-16

PREAI

Mahran, Randa; Kapp, Jonas N.; Valtonen, Salla; Champagne, Allison; Ning, Jinying; Gillette, William; Stephen, Andrew G.; Hao, Feng; Pluckthun, Andreas; Harma, Harri; Pantsar, Tatu; Kopra, Kari

Label-free electronic detection of peptide post-translational modification with functional enzyme-driven assay at the physical limit

CELL REPORTS PHYSICAL SCIENCE

IF7.3

2024-08-01

OAAI

Macchia, Eleonora; Bjorkstrom, Kim; Tewari, Amit; Eskonen, Ville; Luukkonen, Axel; Ghafari, Amir Mohammad; Sarcina, Lucia; Caputo, Mariapia; Tong-Ochoa, Natalia; Kopra, Kari; Pettersson, Fredrik; Gounani, Zahra; Torsi, Luisa; Harma, Harri; Osterbacka, Ronald

Identification of an H-Ras nanocluster disrupting peptide

COMMUNICATIONS BIOLOGY

IF5.1

2024-07-09

OAAI

Steffen, Candy Laura; Manoharan, Ganesh babu; Pavic, Karolina; Yeste-Vazquez, Alejandro; Knuuttila, Matias; Arora, Neha; Zhou, Yong; Harma, Harri; Gaigneaux, Anthoula; Grossmann, Tom N.; Abankwa, Daniel Kwaku

Nanomolar Protein Thermal Profiling with Modified Cyanine Dyes

ANALYTICAL CHEMISTRY

IF6.7

2023-12-07

OAAI

Malakoutikhah, Morteza; Mahran, Randa; Gooran, Negin; Masoumi, Ahmadreza; Lundell, Katri; Liljeblad, Arto; Guiley, Keelan; Dai, Shizhong; Zheng, Qinheng; Zhu, Lawrence; Shokat, Kevan M.; Kopra, Kari; Harma, Harri

Isothermal chemical denaturation assay for monitoring protein stability and inhibitor interactions

SCIENTIFIC REPORTS

IF3.9

2023-11-16

OAAI

Mahran, Randa; Vello, Niklas; Komulainen, Anita; Malakoutikhah, Morteza; Harma, Harri; Kopra, Kari

Homogeneous luminescent quantitation of cellular guanosine and adenosine triphosphates (GTP and ATP) using QT-LucGTP&ATP assay

ANALYTICAL AND BIOANALYTICAL CHEMISTRY

IF3.8

2023-09-16

OAAI

Kopra, Kari; Mahran, Randa; Yli-Hollo, Titta; Tabata, Sho; Vuorinen, Emmiliisa; Fujii, Yuki; Vuorinen, Iida; Ogawa-Iio, Aki; Hirayama, Akiyoshi; Soga, Tomoyoshi; Sasaki, Atsuo T.; Haermae, Harri

Systematic Study of Heteroarene Stacking Using a Congeneric Set of Molecular Glues for Procaspase-6

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-07-05

OAAI

Togo, Takaya; Tram, Linh; Denton, Laura G.; ElHilali-Pollard, Xochina; Gu, Jun; Jiang, Jinglei; Liu, Chenglei; Zhao, Yan; Zhao, Yanlong; Zheng, Yinzhe; Zheng, Yunping; Yang, Jingjing; Fan, Panpan; Arkin, Michelle R.; Harma, Harri; Sun, Deqian; Canan, Stacie S.; Wheeler, Steven E.; Renslo, Adam R.

Rapid high-throughput compatible label-free virus particle quantification method based on time-resolved luminescence

ANALYTICAL AND BIOANALYTICAL CHEMISTRY

IF3.8

2022-05-17

OAAI

Kopra, Kari; Hassan, Nazia; Vuorinen, Emmiliisa; Valtonen, Salla; Mahran, Randa; Habib, Huda; Jalkanen, Pinja; Susi, Petri; Hytonen, Vesa; Hankaniemi, Minna; Yla-Herttuala, Seppo; Kakkola, Laura; Peurla, Markus; Harma, Harri

Sensitive, homogeneous, and label-free protein-probe assay for antibody aggregation and thermal stability studies

MABS

IF7.3

2021-08-30

OAAI

Valtonen, Salla; Vuorinen, Emmiliisa; Eskonen, Ville; Malakoutikhah, Morteza; Kopra, Kari; Harma, Harri

Nanomolar Protein-Protein Interaction Monitoring with a Label-Free Protein-Probe Technique

ANALYTICAL CHEMISTRY

IF6.7

2020-11-25

OAAI

Valtonen, Salla; Vuorinen, Emmiliisa; Kariniemi, Taru; Eskonen, Ville; Le Quesne, John; Bushell, Martin; Harma, Harri; Kopra, Kari

Homogeneous single-label cGMP detection platform for the functional study of nitric oxide-sensitive (soluble) guanylyl cyclases and cGMP-specific phosphodiesterases

SCIENTIFIC REPORTS

IF3.9

2020-10-15

OAAI

Kopra, Kari; Sharina, Iraida; Martin, Emil; Harma, Harri

Single-Peptide TR-FRET Detection Platform for Cysteine-Specific Post-Translational Modifications

ANALYTICAL CHEMISTRY

IF6.7

2020-09-02

OAAI

Eskonen, Ville; Tong-Ochoa, Natalia; Mattsson, Leena; Miettinen, Moona; Lastusaari, Mika; Pulliainen, Arto T.; Kopra, Kari; Harma, Harri

Homogeneous Dual-Parametric-Coupled Assay for Simultaneous Nucleotide Exchange and KRAS/RAF-RBD Interaction Monitoring

ANALYTICAL CHEMISTRY

IF6.7

2020-02-28

OAAI

Kopra, Kari; Vuorinen, Emmiliisa; Abreu-Blanco, Maria; Wang, Qi; Eskonen, Ville; Gillette, William; Pulliainen, Arto T.; Holderfield, Matthew; Harma, Harri

Sensitive Label-Free Thermal Stability Assay for Protein Denaturation and Protein-Ligand Interaction Studies

ANALYTICAL CHEMISTRY

IF6.7

2020-02-04

OAAI

Vuorinen, Emmiliisa; Valtonen, Salla; Eskonen, Ville; Kariniemi, Taru; Jakovleva, Jelena; Kopra, Kari; Harma, Harri

QTR-FRET: Efficient background reduction technology in time-resolved forster resonance energy transfer assays

ANALYTICA CHIMICA ACTA

IF6

2019-12-01

OAAI

Syrjanpaa, Markku; Vuorinen, Emmiliisa; Kulmala, Sakari; Wang, Qi; Harma, Harri; Kopra, Kari

Thermal Dissociation Assay for Time-Resolved Fluorescence Detection of Protein Post-Translational Modifications

ACS OMEGA

IF4.3

2019-09-24

OAAI

Eskonen, Ville; Tong-Ochoa, Natalia; Valtonen, Salla; Kopra, Kari; Harma, Harri

Immunoassays Based on Hot Electron-Induced Electrochemiluminescence at Disposable Cell Chips with Printed Electrodes 基于印刷电极的一次性细胞芯片上的热电子诱导电化学发光的免疫测定

SENSORS

IF3.5

2019-06-19

OAAI

Gronroos, Paivi; Nur-E-Habiba; Salminen, Kalle; Nissinen, Marja; Tuomaala, Tomi; Miikki, Kim; Zhang, Qiang; Wei, Nan; Kauppinen, Esko; Eskola, Jarkko; Harma, Harri; Kulmala, Sakari

Homogeneous peptide-break assay for luminescent detection of enzymatic protein post-translational modification activity utilizing charged peptides

ANALYTICA CHIMICA ACTA

IF6

2019-05-01

PREAI

Kopra, Kari; Tong-Ochoa, Natalia; Laine, Mari; Eskonen, Ville; Koskinen, Paivi J.; Harma, Harri

研究方向