Heini W. Dirr - Publications, H-index & Citations

Heini W. Dirr

University of Witwatersrand

35H指数

139论文数

4.3K被引数

收录论文 27

发表时间

An empirical and theoretical description of Schistosoma japonicum glutathione transferase inhibition by bromosulfophthalein and indanyloxyacetic acid 94

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2021-01-01

PREAI

Pooe, Kagiso; Worth, Roland; Iwuchukwu, Emmanuel Amarachi; Dirr, Heini W.; Achilonu, Ikechukwu

Double trouble? Gag in conjunction with double insert in HIV protease contributes to reduced DRV susceptibility

BIOCHEMICAL JOURNAL

IF4.3

2019-01-31

PREAI

Williams, Alison; Basson, Adriaan; Achilonu, Ikechukwu; Dirr, Heini W.; Morris, Lynn; Sayed, Yasien

V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity

CELL REPORTS

IF6.9

2018-12-01

OAAI

van Eeden, Charmaine; Wibmer, Constantinos Kurt; Scheepers, Cathrine; Richardson, Simone I.; Nonyane, Molati; Lambson, Bronwen; Mkhize, Nonhlanhla N.; Vijayakumar, Balakrishnan; Sheng, Zizhang; Stanfield-Oakley, Sherry; Bhiman, Jinal N.; Bekker, Valerie; Hermanus, Tandile; Mabvakure, Batsirai; Ismail, Arshad; Moody, M. Anthony; Wiehe, Kevin; Garrett, Nigel; Karim, Salim Abdool; Dirr, Heini; Fernandes, Manuel A.; Sayed, Yasien; Shapiro, Lawrence; Ferrari, Guido; Haynes, Barton F.; Moore, Penny L.; Morris, Lynn

A conserved cation binding site in the DNA binding domain of forkhead box transcription factors regulates DNA binding by FOXP2 叉头盒转录因子的DNA结合结构域中的保守阳离子结合位点通过FOXP2调节DNA结合

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

IF3

2018-11-01

PREAI

Morris, Gavin; Pahad, Naadira; Dirr, Heini W.; Fanucchi, Sylvia

Structural and biochemical characterization of Plasmodium falciparum Hsp70-x reveals functional versatility of its C-terminal EEVN motif

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2018-09-29

OAAI

Mabate, Blessing; Zininga, Tawanda; Ramatsui, Lebogang; Makumire, Stanley; Achilonu, Ikechukwu; Dirr, Heini W.; Shonhai, Addmore

(-)-Epigallocatechin-3-Gallate Inhibits the Chaperone Activity of Plasmodium falciparum Hsp70 Chaperones and Abrogates Their Association with Functional Partners

MOLECULES

IF4.6

2017-12-05

OAAI

Zininga, Tawanda; Ramatsui, Lebogang; Makhado, Pertunia Bveledzani; Makumire, Stanley; Achilinou, Ikechukwu; Hoppe, Heinrich; Dirr, Heini; Shonhai, Addmore

The effects of mutating Tyr9 and Arg15 on the structure, stability, conformational dynamics and mechanism of GSTA3-3

BIOPHYSICAL CHEMISTRY

IF2.2

2017-05-01

PREAI

Robertson, Gary J.; Stoychev, Stoyan H.; Sayed, Yasien; Achilonu, Ikechukwu; Dirr, Heini W.

Plasmodium falciparum Hsp70-z, an Hsp110 homologue, exhibits independent chaperone activity and interacts with Hsp70-1 in a nucleotide-dependent fashion

CELL STRESS & CHAPERONES

IF3.2

2016-05-01

OAAI

Zininga, Tawanda; Achilonu, Ikechukwu; Hoppe, Heinrich; Prinsloo, Earl; Dirr, Heini W.; Shonhai, Addmore

Amide hydrogen exchange in HIV-1 subtype B and C proteases - insights into reduced drug susceptibility and dimer stability

FEBS JOURNAL

IF4.2

2014-11-04

OAAI

Naicker, Previn; Stoychev, Stoyan; Dirr, Heini W.; Sayed, Yasien

The Isomerization of Δ5-Androstene-3,17-dione by the Human Glutathione Transferase A3-3 Proceeds via a Conjugated Heteroannular Diene Intermediate

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-11-01

OAAI

Daka, Jonathan L.; Achilonu, Ikechukwu; Dirr, Heini W.

Polymorphic Diversity: N-Phenylbenzamide as a Possible Polymorphophore

CRYSTAL GROWTH & DESIGN

IF3.4

2013-07-18

PREAI

Zipp, Caitlin F.; Dirr, Heini W.; Fernandes, Manuel A.; Marques, Helder M.; Michael, Joseph P.

S-Nitrosation of Glutathione Transferase P1-1 Is Controlled by the Conformation of a Dynamic Active Site Helix

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-05-01

OAAI

Balchin, David; Wallace, Louise; Dirr, Heini W.

Energetics of ligand binding to human glutathione transferase A1-1: Tyr-9 associated localisation of the C-terminal helix is ligand-dependent

BIOPHYSICAL CHEMISTRY

IF2.2

2011-07-01

PREAI

Balchin, David; Dirr, Heini W.; Sayed, Yasien

Arginine 15 stabilizes an SNAr reaction transition state and the binding of anionic ligands at the active site of human glutathione transferase A1-1

BIOPHYSICAL CHEMISTRY

IF2.2

2010-02-01

PREAI

Gildenhuys, Samantha; Dobreva, Marina; Kinsley, Nichole; Sayed, Yasien; Burke, Jonathan; Pelly, Stephen; Gordon, Graeme P.; Sayed, Muhammed; Sewell, Trevor; Dirr, Heini W.

Active-Site Mutations in the South African Human Immunodeficiency Virus Type 1 Subtype C Protease Have a Significant Impact on Clinical Inhibitor Binding: Kinetic and Thermodynamic Study

JOURNAL OF VIROLOGY

IF3.8

2008-11-15

OAAI

Mosebi, Salerwe; Morris, Lynn; Dirr, Heini W.; Sayed, Yasien

Characterization of the binding of 8-anilinonaphthalene sulfonate to rat class Mu GST M1-1

BIOPHYSICAL CHEMISTRY

IF2.2

2008-10-01

OAAI

Kinsley, Nichole; Sayed, Yasien; Mosebi, Salerwe; Armstrong, Richard N.; Dirr, Heini W.