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R

Roman Lesyk

danylo halytsky lviv national medical university

43H指数
394论文数
6.3K被引数
收录论文 70
发表时间
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From Virtual Screening to Cell Phenotype: 4-Thiazolidone Scaffolds Targeting LOXL2 in Breast Cancer从虚拟筛选到细胞表型：靶向乳腺癌中LOXL2的4-噻唑烷酮骨架
errChemical Biology & Drug Design
IF3.3
err2026-05-28
err0
PREAI
errSandra Ferreira; Beatriz Santos; Matilde Tavares; Serhii Holota; Dmytro Khylyuk; Roman Lesyk; Natalia Finyuk; Daniel J. V. A. dos Santos; Ana M. Díaz-Lanza; João G. Costa; Nuno Saraiva; Ana S. Fernandes
err分享
err收藏
A Review of Recent Advances in the Anticancer Mechanisms of Activity of Novel Thiazoles and 4-Thiazolidinones/Thiazolidinediones (2021–2025)新型噻唑和4-噻唑烷二酮/噻唑烷二酮类化合物抗癌活性的机制研究进展综述 (2021–2025)
errMolecules
IF4.6
err2026-04-27
err0
errOAAI
errRostyslav Dudchak; Magdalena Podolak; Anna Bielawska; Krzysztof Bielawski; Roman Lesyk
err分享
err收藏
Promising Anticancer Activity of Novel Hydroxyethyloxy and Bromo derivatives of Curcumin and Its Complexes with BF2新型羟乙氧基和溴代姜黄素及其与BF2的配合物的抗癌活性研究
errMolecules
IF4.6
err2026-03-04
err0
errOAAI
errEduard Potapskyi; Dawid Łażewski; Julian Myszkiewicz; Gabriela Korzańska; Joanna Kuźmińska; Łukasz Popenda; Artur Korzański; Agnieszka Zgoła-Grześkowiak; Agnieszka Gielara-Korzańska; Karolina Chmaj-Wierzchowska; Nataliya Finiuk; Yuliia Kozak; Iryna Ivasechko; Rostyslav Stoika; Roman Lesyk; Marcin Wierzchowski
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Bromo Analogues of Active 3,4,5,4′-Tetramethoxy-trans-stilbene (DMU-212)—A New Path of Research to Anticancer Agents活性3,4,5,4′-四甲氧基-trans-stilbene（DMU-212）的溴代类似物——抗癌药物研究的一条新途径
errMolecules
IF4.6
err2026-03-04
err0
errOAAI
errDawid Łażewski; Gabriela Korzańska; Łukasz Popenda; Karolina Chmaj-Wierzchowska; Artur Korzański; Eduard Potapskyi; Julian Myszkiewicz; Agnieszka Gielara-Korzańska; Agnieszka Zgoła-Grześkowiak; Nataliya Finiuk; Yuliia Kozak; Iryna Ivasechko; Roman Lesyk; Joanna Kuźmińska; Tomasz Goslinski; Marcin Wierzchowski
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err收藏
Synthesis and evaluation of novel 4-thiazolidinone-5-nitrofuran hybrids as promising antimicrobial agents
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2026-01-21
err0
PREAI
errHorishny, Volodymyr; Mural, Dmytro; Kovalenko, Iryna; Finiuk, Nataliya; Ivasechko, Iryna; Konechnyi, Yulian; Tymchuk, Iryna; Nedzelskyi, Stepan; Kozak, Yuliia; Rumynska, Tetyana; Niemczuk, Krzysztof; Szymanska-Czerwinska, Monika; Georgiyants, Victoriya; Stoika, Rostyslav; Lesyk, Roman; Holota, Serhii
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Synthesis and Anticancer Activity Evaluation of New 5-((5-Nitrofuran-2-yl)allylidene)-2-thioxo-4-thiazolidinones新5-((5-硝基呋喃-2-基)烯丙叉)-2-噻唑烷二酮的合成及抗癌活性评价
errPharmaceuticals 2025, Vol. 18, Page 1598
IF0
err2025-10-22
err0
errOAAI
errMagdalena Podolak; Volodymyr Horishny; Rostyslav Dudchak; Agnieszka Gornowicz; Robert Czarnomysy; Dmytro Mural; Serhii Holota; Krzysztof Bielawski; Roman Lesyk; Anna Bielawska
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Design and Optimization of Spiro-Isatin-Thiazolidinone Hybrids with Promising Anticancer Activity螺异噁唑-噻唑烷酮衍生物的设计与优化及其有前景的抗肿瘤活性
errPharmaceuticals 2025, Vol. 18, Page 1502
IF4.8
err2025-10-07
err0
errOAAI
errDmytro Khylyuk; Serhii Holota; Natalia Finiuk; Rostyslav Stoika; Tetyana Rumynska; Roman Lesyk
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A Novel Method of Coupling In Situ Time-Resolved FTIR and Microwave Irradiation: Application to the Monitoring of Quinoxaline Derivatives Synthesis一种耦合原位时间分辨FTIR与微波辐射的新方法：在喹喔啉衍生物合成监测中的应用
errMolecules 2025, Vol. 30, Page 3875
IF4.6
err2025-09-26
err0
errOAAI
errAlina Cherniienko; Kacper Kossakowski; Lucjusz Zaprutko; Roman Lesyk; Dorota Olender; Anna Pawełczyk
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MOLECULES WITH ALKYNE FRAGMENT IN MEDICINAL CHEMISTRY: THE PATH FROM NEUROTOXINS TO DRUGS含炔烃片段的药物化学分子：从神经毒素到药物
errEuropean Journal of Medicinal Chemistry Reports
IF4.1
err2025-08-18
err0
errOAAI
errNataliya Zelisko; Roman Lesyk
err分享
err收藏
Synthesis and anticancer activity evaluation of new linked/fused bioisosteric pyrazole-thiazole-bearing hybrid molecules新型连接/稠合生物电子等排体吡唑-噻唑类杂化分子的合成与抗癌活性评价
errBioorganic & Medicinal Chemistry
IF3
err2025-06-22
err0
PREAI
errIhor Yushyn; Serhii Holota; Nataliya Finiuk; Julia Senkiv; Olexandr Karpenko; Orysya Vovchuk; Yuliia Kozak; Iryna Ivasechko; Roman Pinyazhko; Andrzej Gzella; Piotr Świątek; Rostyslav Stoika; Roman Lesyk
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Synthesis, physicochemical characterization and biological activity of novel pyrrole flavones
errSCIENTIFIC REPORTS
IF3.9
err2025-03-03
err0
errOAAI
errSysak, Stepan; Wicher, Barbara; Kucinska, Malgorzata; Kobylka, Paulina; Mlynarczyk, Dariusz T.; Lesyk, Roman; Tykarska, Ewa; Murias, Marek; Goslinski, Tomasz; Szczolko, Wojciech
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Efficacy of thiazole derivatives against colorectal cancer induced by dimethylhydrazine in male Wistar rats噻唑衍生物对二甲基肼诱导的雄性Wistar大鼠结肠癌的疗效
errBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
IF2.2
err2025-03-01
err0
PREAI
errFomenko, Iryna; Denysenko, Nataliia; Lozynska, Iryna; Kuryk, Mariana; Yushyn, Ihor; Myhal, Ostap; Pinyazhko, Roman; Lozynskyi, Andrii; Lesyk, Roman
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Novel endocytosis inhibitors block entry of HIV-1 Tat into neural cells
errAMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
IF4.7
err2025-02-01
err0
PREAI
errSzewczyk-Roszczenko, Olga Klaudia; Roszczenko, Piotr; Shmakova, Anna; Yushyn, Ihor; Holota, Serhii; Karpenko, Olexandr; Czarnomysy, Robert; Bielawska, Anna; Vassetzky, Yegor; Lesyk, Roman; Bielawski, Krzysztof
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New Hydrazone Derivatives Based on Pyrazolopyridothiazine Core as Cytotoxic Agents to Colon Cancers: Design, Synthesis, Biological Evaluation, and Molecular Modeling
errCHEMMEDCHEM
IF3.4
err2025-01-21
err1
PREAI
errGlomb, Teresa; Sroda-Pomianek, Kamila; Palko-Labuz, Anna; Wesolowska, Olga; Wikiera, Agnieszka; Wojtkowiak, Kamil; Jezierska, Aneta; Kochel, Andrzej; Lesyk, Roman; Swiatek, Piotr
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PEG-Polymeric Nanocarriers Alleviate the Immunosuppressive Effects of Free 4-Thiazolidinone-Based Chemotherapeutics on T Lymphocyte Function and Cytokine Production
errINTERNATIONAL JOURNAL OF NANOMEDICINE
IF6.5
err2024-12-01
err0
errOAAI
errTulinska, Jana; Kobylinska, Lesya; Mikusova, Miroslava Lehotska; Babincova, Julia; Mitina, Natalia; Rollerova, Eva; Liskova, Aurelia; Madrova, Nikola; Alacova, Radka; Zaichenko, Alexander; Lesyk, Roman; Horvathova, Mira; Szabova, Michaela; Lukan, Norbert; Vari, Sandor
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Trastuzumab Potentiates Antitumor Activity of Thiopyrano[2,3-d]Thiazole Derivative in AGS Gastric Cancer Cells
errMOLECULES
IF4.6
err2024-10-30
err0
errOAAI
errRoszczenko, Piotr; Szewczyk-Roszczenko, Olga Klaudia; Gornowicz, Agnieszka; Czarnomysy, Robert; Lozynskyi, Andrii; Bielawski, Krzysztof; Lesyk, Roman; Bielawska, Anna
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IR-EcoSpectra: Exploring sustainable ex situ and in situ FTIR applications for green chemical and pharmaceutical analysis
errJOURNAL OF PHARMACEUTICAL ANALYSIS
IF8.9
err2024-09-01
err5
errOAAI
errCherniienko, Alina; Lesyk, Roman; Zaprutko, Lucjusz; Pawelczyk, Anna
err分享
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Role of 4-Thiazolidinone-Pyrazoline/Indoline Hybrids Les-4369 and Les-3467 in BJ and A549 Cell Lines
errCELLS
IF5.2
err2024-06-08
err2
errOAAI
errKosinska, Karolina; Skora, Bartosz; Holota, Serhii; Shepeta, Yulia; Tabecka-Lonczynska, Anna; Lesyk, Roman; Szychowski, Konrad A.
err分享
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A New 4-Thiazolidinone Derivative (Les-6490) as a Gut Microbiota Modulator: Antimicrobial and Prebiotic Perspectives
errANTIBIOTICS-BASEL
IF4.6
err2024-03-22
err0
errOAAI
errKonechnyi, Yulian; Rumynska, Tetyana; Yushyn, Ihor; Holota, Serhii; Turkina, Vira; Ryviuk Rydel, Mariana; Sekowska, Alicja; Salyha, Yuriy; Korniychuk, Olena; Lesyk, Roman
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Thiadiazole and Thiazole Derivatives as Potential Antimicrobial Agents噻二唑和噻唑衍生物作为潜在的抗菌剂
errMINI-REVIEWS IN MEDICINAL CHEMISTRY
IF3.3
err2024-03-01
err7
PREAI
errKhamitova, Akzhonas; Berillo, Dmitriy; Lozynskyi, Andrii; Konechnyi, Yulian; Mural, Dmytro; Georgiyants, Victoriya; Lesyk, Roman
err分享
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研究方向

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