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Qi Chen

Northeast Normal University
H指数:17
被引数:1,303

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Structural determinants of dual incretin receptor agonism by tirzepatide

tirzepatide双重肠促胰岛素受体激动作用的结构决定因素

2022-03-2552
OAAI
Synthesis and Preclinical Characterization of LY3154885, a Human Dopamine D1 Receptor Positive Allosteric Modulator with an Improved Nonclinical Drug-Drug Interaction Risk Profile
2022-02-173
PRE
Discovery of an Orally Efficacious Positive Allosteric Modulator of the Glucagon-like Peptide-1 Receptor
2021-03-1514
PREAI
Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (LY3154207), a Potent, Subtype Selective, and Orally Available Positive Allosteric Modulator of the Human Dopamine D1 Receptor
2019-09-1845
PREAI
Synthesis and Pharmacological Characterization of C4β-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1S,2S,4S,5R,6S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Highly Potent and Selective mGlu3 Receptor Agonist
2018-01-1922
PREAI
The Discovery, Preclinical, and Early Clinical Development of Potent and Selective GPR40 Agonists for the Treatment of Type 2 Diabetes Mellitus (LY2881835, LY2922083, and LY2922470)
2016-11-1156
OAAI
Identification of LY2510924, a Novel Cyclic Peptide CXCR4 Antagonist That Exhibits Antitumor Activities in Solid Tumor and Breast Cancer Metastatic Models

鉴定LY2510924,一种在实体瘤和乳腺癌转移模型中表现出抗肿瘤活性的新型环肽CXCR4拮抗剂

2015-02-09136
OAAI