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M

Michael L. Vazquez

medicine design, pfizer inc, cambridge, massachusetts 02139, united states
H指数:16
被引数:840

个人简介

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教育背景

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工作经历

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荣誉奖项

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Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists

甲基在环己烷取代的squaramide CCR6拮抗剂效力中的构象作用

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2025-02-171
PRE
Gerstenberger, Brian S.; Unwalla, Ray; Farley, Kathleen A.; Nuhant, Philippe; Lombardo, Vincent M.; Li, Wei; Crouse, Kimberly; Frisbie, Richard K.; Arnold, Eric P.; Bundesmann, Mark W.; Chinigo, Gary M.; Flick, Andrew; Kaila, Neelu; Lamb, Daniel; Mousseau, James J.; Niljianskul, Nootaree; Rappas, Mathieu; Trujillo, John I.; Vazquez, Michael L.; Thorarensen, Atli; Schnute, Mark E.
Identification of N-{cis-3-(Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)aminolcyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2018-01-23134
OAAI
Vazquez, Michael L.; Kaila, Neelu; Strohbach, Joseph W.; Trzupek, John D.; Brown, Matthew F.; Flanagan, Mark E.; Mitton-Fry, Mark J.; Johnson, Timothy A.; TenBrink, Ruth E.; Arnold, Eric P.; Basak, Arindrajit; Heasley, Steven E.; Kwon, Soojin; Langille, Jonathan; Parikh, Mihir D.; Griffin, Sarah H.; Casavant, Jeffrey M.; Duclos, Brian A.; Fenwick, Ashley E.; Harris, Thomas M.; Han, Seungil; Caspers, Nicole; Dowty, Martin E.; Yang, Xin; Banker, Mary Ellen; Hegen, Martin; Symanowicz, Peter T.; Li, Li; Wang, Lu; Lin, Tsung H.; Jussif, Jason; Clark, James D.; Telliez, Jean-Baptiste; Robinson, Ralph P.; Unwalla, Ray
Synthesis, crystal structure, and activity of pyrazole-based inhibitors of p38 kinase
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2007-10-1963
PREAI
Graneto, Matthew J.; Kurumbail, Ravi G.; Vazquez, Michael L.; Shieh, Huey-Sheng; Pawlitz, Jennifer L.; Williams, Jennifer M.; Stallings, William C.; Geng, Lifeng; Naraian, Ashok S.; Koszyk, Francis J.; Stealey, Michael A.; Xu, Xiangdong D.; Weier, Richard M.; Hanson, Gunnar J.; Mourey, Robert J.; Compton, Robert P.; Mnich, Stephen J.; Anderson, Gary D.; Monahan, Joseph B.; Devraj, Rajesh
Discovery of PF-07054894; a Potent Squaramide-Based CCR6 Antagonist Displaying High CXCR2 Selectivity

发现PF-07054894：一种强效的基于四嗪酰胺的CCR6拮抗剂，表现出对CXCR2的高选择性

Journal of Medicinal Chemistry
IF6.8
0
PRE
Mark E. Schnute; Huixian Wu; John I. Trujillo; Wei Li; David Jonathan Wasilko; Jennifer Alley; Eric P. Arnold; Scott W. Bagley; Gabriel Berstein; David C. Blakemore; Mark W. Bundesmann; Gary M. Chinigo; Chulho Choi; Robert Cooke; Kimberly Crouse; Alpay Dermenci; Theresa Dickinson; Andrew Flick; Richard K. Frisbie; Carmen Garcia-Irizarry; Brian S. Gerstenberger; David Hepworth; Neelu Kaila; Daniel W. Kung; Daniel Lamb; Sophie Y. Lavergne; David C. Limburg; Shenping Liu; Vincent M. Lombardo; Prolay K. Mondal; James J. Mousseau; Arjun Narayanan; Nootaree Niljianskul; Philippe Nuhant; Senliang Pan; Michael J. Primiano; Mathieu Rappas; Daniel C. Schmitt; Stefanus J. Steyn; Ray Unwalla; Dipy Vasa; Michael L. Vazquez; Fabien Vincent; Xiaojing Yang; Atli Thorarensen

研究方向

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R
Ray Unwalla
H 指数:17论文数:31被引数:1,274
M
Mark E. Schnute
H 指数:25论文数:55被引数:2,358
J
John I. Trujillo
H 指数:21论文数:133被引数:2,013
A
Andrew C. Flick
H 指数:24论文数:75被引数:1,895
N
Neelu Kaila
H 指数:26论文数:68被引数:1,888
P
Philippe Nuhant
H 指数:20论文数:72被引数:1,932
A
Atli Thorarensen
H 指数:30论文数:79被引数:3,182
K
Kimberly Crouse
H 指数:6论文数:20被引数:285
V
Vincent M. Lombardo
H 指数:4论文数:19被引数:54
E
Eric P. Arnold
H 指数:15论文数:45被引数:1,814