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科言猫学术研究的AI总结
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K

Karthik Srinivasan

university of california san francisco

4H指数
16论文数
148被引数
收录论文 5
发表时间
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Development of a random background to understand ligand optimization开发随机背景以理解配体优化
errNature
IF48.5
err2026-09-16
err0
errOAAI
errXinyu Xu; Olivier Mailhot; Galen J. Correy; Xi-Ping Huang; Joao M. Braz; Da Shi; Karthik Srinivasan; Kara Zielinski; Yuliia Holota; Yuliia Kuziv; Christos Iliopoulos-Tsoutsouvas; Nathan D. Levinzon; Yagmur U. Doruk; Moira M. Rachman; Morgan E. Diolaiti; Maisie G. V. Stevens; Fangyu Liu; Katie L. Holland; Harald Hübner; Jing Wang; Yujin Wu; Alan Ashworth; Alexandros Makriyannis; Yuqi Zhang; Yurii S. Moroz; Peter Gmeiner; Robert Abel; Aashish Manglik; Allan I. Basbaum; Bryan L. Roth; James S. Fraser; Brian K. Shoichet
err分享
err收藏
Hypervariable loop profiling decodes sequence determinants of antibody stability超变环分析解码抗体稳定性的序列决定因素
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2026-04-30
err0
PREAI
errYue Wan; Jiahao Liang; Yile Dai; Karthik Srinivasan; Christian Billesbølle; Ju-Fen Zhu; Jung-Eun Shin; Steffanie Paul; Debora Marks; Yun S. Song; Benjamin R. Myers; Antoine Koehl; Aashish Manglik
err分享
err收藏
Large Library Docking for Polypharmacology高通量对接在多药效学中的应用
errJournal of Medicinal Chemistry
IF6.8
err2026-02-01
err0
errOAAI
errWu, Yujin; Vigneron, Seth; Braz, Joao; Srinivasan, Karthik; Fink, Elissa A.; Huang, Xi-Ping; Xu, Xinyu; Huebner, Harald; Kim, Joseph Y.; Wang, Jing; Pfeiffer, Tara; Sakamoto, Kensuke; Radchenko, Dmytro S.; Rodriguiz, Ramona M.; Moroz, Yurii S.; Irwin, John J.; Gmeiner, Peter; Billesboelle, Christian; Roth, Bryan L.; Basbaum, Allan I.; Manglik, Aashish; Wetsel, William C.; Shoichet, Brian K.
err分享
err收藏
Docking 14 Million Virtual Isoquinuclidines against the μ and κ Opioid Receptors Reveals Dual Antagonists-Inverse Agonists with Reduced Withdrawal Effects对接1400万种虚拟异喹啉啶化合物与μ和κ阿片受体，发现具有双重拮抗剂-反向激动剂特性且戒断效应减弱的化合物
errACS CENTRAL SCIENCE
IF10.4
err2025-04-29
err0
errOAAI
errVigneron, SF; Ohno, S; Braz, J; Kim, JY; Kweon, OS; Webb, C; Billesbolle, CB; Srinivasan, K; Bhardwaj, K; Irwin, JJ; Manglik, A; Basbaum, AI; Ellman, JA; Shoichet, BK
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err收藏
Probing the Plasticity in the Active Site of Protein N-terminal Methyltransferase 1 Using Bisubstrate Analogues
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-07-01
err20
errOAAI
errChen, Dongxing; Dong, Cheng; Dong, Guangping; Srinivasan, Karthik; Min, Jinrong; Noinaj, Nicholas; Huang, Rong
err分享
err收藏

研究方向

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合作学者
合作期刊
B
Bryan L. Roth
H 指数: 139 · 论文数: 971
A
Alan Ashworth
H 指数: 121 · 论文数: 1.0K
B
Brian K. Shoichet
H 指数: 114 · 论文数: 416
A
Allan I. Basbaum
H 指数: 113 · 论文数: 386
J
Jonathan A. Ellman
H 指数: 104 · 论文数: 663
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