Christopher D. Link - Publications, H-index & Citations

Christopher D. Link

University System of Maryland

49H指数

114论文数

9.6K被引数

收录论文 49

发表时间

Sleep-wake behavior and responses to sleep deprivation and immune challenge of protein kinase RNA-activated knockout mice 蛋白激酶RNA激活的敲除小鼠的睡眠-觉醒行为和对睡眠剥夺和免疫攻击的反应

BRAIN BEHAVIOR AND IMMUNITY

IF7.6

2024-10-01

OAAI

Valencia-Sanchez, S.; Davis, M.; Martensen, J.; Hoeffer, C.; Link, C.; Opp, M. R.

PKR regulates sleep-wake behavior and its homeostatic responses to sleep deprivation and LPS administration in mice

BRAIN BEHAVIOR AND IMMUNITY

IF7.6

2023-11-01

PREAI

Valencia, Salvador; Hoeffer, Charles; Link, Christopher D.; Opp, Mark R.

COVID-19 IN-HOSPITAL OUTCOMES AND PREDICTORS OF MORTALITY IN PATIENTS WITH SOLID ORGAN TRANSPLANT

CHEST

IF8.6

2023-10-01

OAAI

Virk, Shiza; Alhuneafat, Laith; Khalid, Muhammad Umar; Jabri, Ahmed; Deicke, Matthew; Jacobs, Max; Link, Christopher; Shah, Aaisha A.; Rana, Tabeer

The reverse transcriptase inhibitor 3TC protects against age-related cognitive dysfunction

AGING CELL

IF7.1

2023-03-22

OAAI

Wahl, Devin; Smith, Meghan E.; McEntee, Cali M.; Cavalier, Alyssa N.; Osburn, Shelby C.; Burke, Samuel D.; Grant, Randy A.; Nerguizian, David; Lark, Daniel S.; Link, Christopher D.; LaRocca, Thomas J.

The Caenorhabditis elegans Ortholog of TDP-43 Regulates the Chromatin Localization of the Heterochromatin Protein 1 Homolog HPL-2

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-03

OAAI

Saldi, Tassa K.; Gonzales, Patrick; Garrido-Lecca, Alfonso; Dostal, Vishantie; Roberts, Christine M.; Petrucelli, Leonard; Link, Christopher D.

Identifying an Optimal Neuroinflammation Treatment Using a Nanoligomer Discovery Engine

ACS CHEMICAL NEUROSCIENCE

IF3.9

2022-11-21

OAAI

Sharma, Sadhana; Borski, Curtis; Hanson, Jessica; Garcia, Micklaus A.; Link, Christopher D.; Hoeffer, Charles; Chatterjee, Anushree; Nagpal, Prashant

Amyloid beta acts synergistically as a pro-inflammatory cytokine

NEUROBIOLOGY OF DISEASE

IF5.6

2021-11-01

OAAI

LaRocca, Thomas J.; Cavalier, Alyssa N.; Roberts, Christine M.; Lemieux, Maddie R.; Ramesh, Pooja; Garcia, Micklaus A.; Link, Christopher D.

The gut microbiome-derived metabolite trimethylamineN-oxide modulates neuroinflammation and cognitive function with aging

GEROSCIENCE

IF5.4

2020-08-29

117

OAAI

Brunt, Vienna E.; LaRocca, Thomas J.; Bazzoni, Amy E.; Sapinsley, Zachary J.; Miyamoto-Ditmon, Jill; Gioscia-Ryan, Rachel A.; Neilson, Andrew P.; Link, Christopher D.; Seals, Douglas R.

TDP-43 knockdown causes innate immune activation via protein kinase R in astrocytes TDP-43敲低通过星形胶质细胞中的蛋白激酶R引起先天免疫激活

NEUROBIOLOGY OF DISEASE

IF5.6

2019-12-01

OAAI

LaRocca, Thomas J.; Mariani, Andrea; Watkins, Linda R.; Link, Christopher D.

α-Sheet secondary structure in amyloid β-peptide drives aggregation and toxicity in Alzheimer's disease

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-04-19

135

OAAI

Shea, Dylan; Hsu, Cheng-Chieh; Bi, Timothy M.; Paranjapye, Natasha; Childers, Matthew Carter; Cochran, Joshua; Tomberlin, Colson P.; Wang, Libo; Paris, Daniel; Zonderman, Jeffrey; Varani, Gabriele; Link, Christopher D.; Mullan, Mike; Daggett, Valerie

Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation 谷胱甘肽氧化还原稳态的丧失通过抑制自噬依赖性蛋白降解而损害蛋白平衡

CELL DEATH AND DIFFERENTIATION

IF15.4

2019-02-15

OAAI

Guerrero-Gomez, David; Antonio Mora-Lorca, Jose; Saenz-Narciso, Beatriz; Jose Naranjo-Galindo, Francisco; Munoz-Lobato, Fernando; Parrado-Fernandez, Cristina; Goikolea, Julen; Cedazo-Minguez, Angel; Link, Christopher D.; Neri, Christian; Dolores Sequedo, Maria; Vazquez-Manrique, Rafael P.; Fernandez-Suarez, Elena; Goder, Veit; Pane, Roser; Cabiscol, Elisa; Askjaer, Peter; Cabello, Juan; Miranda-Vizuete, Antonio

In vivo induction of membrane damage by β-amyloid peptide oligomers

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2018-11-29

OAAI

Julien, Carl; Tomberlin, Colson; Roberts, Christine M.; Akram, Aumbreen; Stein, Gretchen H.; Silverman, Michael A.; Link, Christopher D.

RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome RNA自组装有助于应激颗粒形成和定义应激颗粒转录组

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-02-26

355

OAAI

Van Treeck, Briana; Protter, David S. W.; Matheny, Tyler; Khong, Anthony; Link, Christopher D.; Parker, Roy

Repetitive element transcripts are elevated in the brain of C9orf72 ALS/FTLD patients

HUMAN MOLECULAR GENETICS

IF3.2

2017-06-16

OAAI

Prudencio, Mercedes; Gonzales, Patrick K.; Cook, Casey N.; Gendron, Tania F.; Daughrity, Lillian M.; Song, Yuping; Ebbert, Mark T. W.; van Blitterswijk, Marka; Zhang, Yong-Jie; Jansen-West, Karen; Baker, Matthew C.; DeTure, Michael; Rademakers, Rosa; Boylan, Kevin B.; Dickson, Dennis W.; Petrucelli, Leonard; Link, Christopher D.

Caenorhabditis elegans as a model system to study post-translational modifications of human transthyretin

SCIENTIFIC REPORTS

IF3.9

2016-11-21

OAAI

Henze, Andrea; Homann, Thomas; Rohn, Isabelle; Aschner, Michael; Link, Christopher D.; Kleuser, Burkhard; Schweigert, Florian J.; Schwerdtle, Tanja; Bornhorst, Julia

Identifying Aβ-specific pathogenic mechanisms using a nematode model of Alzheimer's disease 使用阿尔茨海默氏病的线虫模型鉴定a β 特异性致病机制

NEUROBIOLOGY OF AGING

IF3.5

2015-02-01

OAAI

Hassan, Wail M.; Dostal, Vishantie; Huemann, Brady N.; Yerg, John E.; Link, Christopher D.

TDP-1, the Caenorhabditis elegans ortholog of TDP-43, limits the accumulation of double-stranded RNA

EMBO JOURNAL

IF8.3

2014-11-12

OAAI

Saldi, Tassa K.; Ash, Peter E. A.; Wilson, Gavin; Gonzales, Patrick; Garrido-Lecca, Alfonso; Roberts, Christine M.; Dostal, Vishantie; Gendron, Tania F.; Stein, Lincoln D.; Blumenthal, Thomas; Petrucelli, Leonard; Link, Christopher D.

Decreased insulin-receptor signaling promotes the autophagic degradation of β-amyloid pepticle in C. elegans. (vol 3, pg 569, 2007)

AUTOPHAGY

IF14.3

2014-10-27

OAAI

Florez-McClure, Maria L.; Link, Christopher D.

Decreased insulin-receptor signaling promotes the autophagic degradation of β-amyloid peptide in C-elegans

AUTOPHAGY

IF14.3

2014-10-27

129

OAAI

Florez-McClure, Maria L.; Hohsfield, Lindsay A.; Fonte, Gin; Bealor, Matthew T.; Link, Christopher D.

A glycine zipper motif mediates the formation of toxic β-amyloid oligomers in vitro and in vivo (vol 6, pg 61, 2011)

MOLECULAR NEURODEGENERATION

IF17.5

2014-03-25

OAAI

Fonte, Virginia; Dostal, Vishantie; Roberts, Christine M.; Gonzales, Patrick; Lacor, Pascale N.; Velasco, Pauline T.; Magrane, Jordi; Dingwell, Natalie; Fan, Emily Y.; Silverman, Michael A.; Stein, Gretchen H.; Link, Christopher D.

研究方向