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Iqra Ajmal

guangdong provincial key laboratory of medical immunology and molecular diagnostics

H指数:13

被引数:832

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Advanced strategies to enhance the safety; persistence; and efficacy of CAR-T cells in solid tumors

增强实体瘤中CAR-T细胞安全性、持久性和疗效的先进策略

Frontiers in Immunology

IF5.9

2026-05-200

OAAI

KLRG1 silencing increases the efficacy of CAR NK cell therapy against colon cancer via SHP-2/ZAP-70/NF-κB signal pathway

KLRG1沉默通过SHP-2/ZAP-70/NF-κB信号通路增强CAR NK细胞疗法对结肠癌的治疗效果

Journal of Translational Medicine

IF7.5

2026-05-140

OAAI

Overexpression of HIF-1α via small activating RNA enhances CAR-T cell function in hypoxic microenvironments

通过小激活RNA介导的HIF-1α过表达增强CAR-T细胞在缺氧微环境中的功能

Pharmacological Research

IF10.5

2026-05-070

OAAI

TIPE2 knockdown enhances the anti-tumor efficacy of NKG2D CAR-T cells against pancreatic cancer via activating NF-κb signaling pathway

TIPE2敲低通过激活NF-κb信号通路增强NKG2D CAR-T细胞对胰腺癌的抗肿瘤疗效

Journal of Translational Medicine

IF7.5

2026-02-140

OA

Chimeric cytokine receptor TGF-β RII/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer

嵌合细胞因子受体TGF-β RII/IL-21R通过逆转胃癌免疫抑制性肿瘤微环境来改善CAR-NK细胞功能

PHARMACOLOGICAL RESEARCH

IF10.5

2025-02-011

OAAI

A novel strategy of co-expressing CXCR5 and IL-7 enhances CAR-T cell effectiveness in osteosarcoma

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-10-100

OAAI

shRNA-mediated gene silencing of HDAC11 empowers CAR-T cells against prostate cancer

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-05-212

OAAI

Modulating Cholesterol Metabolism via ACAT1 Knockdown Enhances Anti-B-Cell Lymphoma Activities of CD19-Specific Chimeric Antigen Receptor T Cells by Improving the Cell Activation and Proliferation

IF5.2

2024-03-214

OAAI

Co-expression of IL-4/IL-15-based inverted cytokine receptor in CAR-T cells overcomes IL-4 signaling in immunosuppressive pancreatic tumor microenvironment

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2023-12-019

OAAI

An overview of viral mutagenesis and the impact on pathogenesis of SARS-CoV-2 variants

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-11-2811

OAAI

Suppression of 4.1R enhances the potency of NKG2D-CAR T cells against pancreatic carcinoma via activating ERK signaling pathway

IF6.4

2021-09-2115

OAAI

Microbes as Biofertilizers, a Potential Approach for Sustainable Crop Production

微生物作为生物肥料，可持续作物生产的潜在方法

IF3.3

2021-02-09181

OAAI