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A large-scale genome-wide study of gene-sleep duration interactions for blood pressure in 811,405 individuals from diverse populations 一项大规模的全基因组研究，探讨了811,405名来自不同人群的个体中基因与睡眠时长对血压的交互作用。 Nagarajan, Pavithra; Winkler, Thomas W.; Bentley, Amy R.; Miller, Clint L.; Kraja, Aldi T.; Schwander, Karen; Lee, Songmi; Wang, Wenyi; Brown, Michael R.; Morrison, John L.; Giri, Ayush; O'Connell, Jeffrey R.; Bartz, Traci M.; de las Fuentes, Lisa; Gudmundsdottir, Valborg; Guo, Xiuqing; Harris, Sarah E.; Huang, Zhijie; Kals, Mart; Kho, Minjung; Lefevre, Christophe; Luan, Jian'an; Lyytikainen, Leo-Pekka; Mangino, Massimo; Milaneschi, Yuri; Palmer, Nicholette D.; Rao, Varun; Rauramaa, Rainer; Shen, Botong; Stadler, Stefan; Sun, Quan; Tang, Jingxian; Theriault, Sebastien; van der Graaf, Adriaan; van der Most, Peter J.; Wang, Yujie; Weiss, Stefan; Westerman, Kenneth E.; Yang, Qian; Yasuharu, Tabara; Zhao, Wei; Zhu, Wanying; Altschul, Drew; Ansari, Md Abu Yusuf; Anugu, Pramod; Argoty-Pantoja, Anna D.; Arzt, Michael; Aschard, Hugues; Attia, John R.; Bazzanno, Lydia; Breyer, Max A.; Brody, Jennifer A.; Cade, Brian E.; Chen, Hung-hsin; Chen, Yii-Der Ida; Chen, Zekai; de Vries, Paul S.; Dimitrov, Latchezar M.; Do, Anh; Du, Jiawen; Dupont, Charles T.; Edwards, Todd L.; Evans, Michele K.; Faquih, Tariq; Felix, Stephan B.; Fisher-Hoch, Susan P.; Floyd, James S.; Graff, Mariaelisa; Gu, Charles; Gu, Dongfeng; Hairston, Kristen G.; Hanley, Anthony J.; Heid, Iris M.; Heikkinen, Sami; Highland, Heather M.; Hood, Michelle M.; Kaehoenen, Mika; Karvonen-Gutierrez, Carrie A.; Kawaguchi, Takahisa; Kazuya, Setoh; Kelly, Tanika N.; Komulainen, Pirjo; Levy, Daniel; Lin, Henry J.; Liu, Peter Y.; Marques-Vidal, Pedro; McCormick, Joseph B.; Mei, Hao; Meigs, James B.; Menni, Cristina; Nam, Kisung; Nolte, Ilja M.; Pacheco, Natasha L.; Petty, Lauren E.; Polikowsky, Hannah G.; Province, Michael A.; Psaty, Bruce M.; Raffield, Laura M.; Raitakari, Olli T.; Rich, Stephen S.; Riha, Renata L.; Risch, Lorenz; Risch, Martin; Ruiz-Narvaez, Edward A.; Scott, Rodney J.; Sitlani, Colleen M.; Smith, Jennifer A.; Sofer, Tamar; Teder-Laving, Maris; Voelker, Uwe; Vollenweider, Peter; Wang, Guanchao; Willems van Dijk, Ko; Wilson, Otis D.; Xia, Rui; Yao, Jie; Young, Kristin L.; Zhang, Ruiyuan; Zhu, Xiaofeng; Below, Jennifer E.; Boeger, Carsten A.; Conen, David; Cox, Simon R.; Doerr, Marcus; Feitosa, Mary F.; Fox, Ervin R.; Franceschini, Nora; Gharib, Sina A.; Gudnason, Vilmundur; Harlow, Sioban D.; He, Jiang; Holliday, Elizabeth G.; Kutalik, Zoltan; Lakka, Timo A.; Lawlor, Deborah A.; Lee, Seunggeun; Lehtimaki, Terho; Li, Changwei; Liu, Ching-Ti; Magi, Reedik; Matsuda, Fumihiko; Morrison, Alanna C.; Penninx, Brenda W. J. H.; Peyser, Patricia A.; Rotter, Jerome I.; Snieder, Harold; Spector, Tim D.; Wagenknecht, Lynne E.; Wareham, Nicholas J.; Zonderman, Alan B.; North, Kari E.; Fornage, Myriam; Hung, Adriana M.; Manning, Alisa K.; Gauderman, James; Chen, Han; Munroe, Patricia B.; Rao, Dabeeru C.; van Heemst, Diana; Redline, Susan; Noordam, Raymond; Wang, Heming; Muralidhar, Sumitra; Moser, Jennifer; Deen, Jennifer E.; Tsao, Philip S.; Gaziano, J. Michael; Hauser, Elizabeth; Kilbourne, Amy; Matheny, Michael; Oslin, Dave; Churby, Lori; Whitbourne, Stacey B.; Brewer, Jessica, V; Shayan, Shahpoor Alex; Selva, Luis E.; Pyarajan, Saiju; Cho, Kelly; Duvall, Scott L.; Brophy, Mary T.; Stephens, Brady; Connor, Todd; Argyres, Dean P.; Assimes, Themistocles L.; Hung, Adriana; Kranzler, Henry; Aguayo, Samuel; Ahuja, Sunil; Alexander, Kathrina; Androulakis, Xiao M.; Balasubramanian, Prakash; Ballas, Zuhair; Bast, Elizabeth S.; Beckham, Jean; Bhushan, Sujata; Boyko, Edward; Cohen, David; Dellitalia, Louis; Dryden, Jr Gerald Wayne; Faulk, L. Christine; Fayad, Joseph; Fujii, Daryl; Gappy, Saib; Gesek, Frank; Greco, Jennifer; Godschalk, Michael; Gress, Todd W.; Gupta, Samir; Gutierrez, Salvador; Harley, John; Hamner, Mark; Hogan, Daniel J.; Hurley, Robin; Iruvanti, Pran; Jacono, Frank; Jhala, Darshana; Kinlay, Scott; Landry, Michael; Liang, Peter; Liangpunsakul, Suthat; Lichy, Jack; Lo, Tze Shien; Mahan, C. Scott; Marrache, Ronnie; Mastorides, Stephen; Mattocks, Kristin; Meyer, Paul; Moorman, Jonathan; Morales, Providencia; Morgan, Timothy; Murdoch, Maureen; Naik, Eknath; Norton, James; Okusaga, Olaoluwa; Ong, Michael K.; Oursler, Kris Ann; Petrakis, Ismene; Poon, Samuel; Potter, Emily; Rauchman, Michael; Rai, Amneet S.; Servatius, Richard; Sharma, Satish; Smith, River; Sriram, Peruvemba; Strollo, Jr Patrick; Tandon, Neeraj; Villareal, Gerardo; Walsh, Jessica; Wells, John; Whittle, Jeffrey; Whooley, Mary; Wilson, Peter; Xu, Junzhe; Yeh, Shing Shing; Yen, Andrew W. 分享 收藏
Chimeric cytokine receptor TGF-β RII/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer 嵌合细胞因子受体TGF-β RII/IL-21R通过逆转胃癌免疫抑制性肿瘤微环境来改善CAR-NK细胞功能 Ren, Yaojun; Xue, Min; Hui, Xinhui; Liu, Xiuyu; Farooq, Muhammad Asad; Chen, Yiran; Ji, Yuzhou; Duan, Yixin; Ajmal, Iqra; Yao, Jie 分享 收藏
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Association of Polygenic Risk Scores with Aortic Valve Calcium: The Multi-Ethnic Study of Atherosclerosis (MESA) 多基因风险评分与主动脉瓣钙化的关联：动脉粥样硬化多种族研究（MESA） Whelton, Seamus; Yao, Jie; Clish, Clary; Wood, Alexis; Taylor, Kent; Blaha, Michael; Marrero, Natalie; Thanassoulis, George; Post, Wendy; Guo, Xiuqing; Rotter, Jerome 分享 收藏
Association analysis between an epigenetic alcohol risk score and blood pressure 表观遗传酒精风险评分与血压的关联分析 Bui, Helena; Keshawarz, Amena; Wang, Mengyao; Lee, Mikyeong; Ratliff, Scott M.; Lin, Lisha; Birditt, Kira S.; Faul, Jessica D.; Peters, Annette; Gieger, Christian; Delerue, Thomas; Kardia, Sharon L. R.; Zhao, Wei; Guo, Xiuqing; Yao, Jie; Rotter, Jerome I.; Li, Yi; Liu, Xue; Liu, Dan; Tavares, Juliana F.; Pehlivan, Goekhan; Breteler, Monique M. B.; Karabegovic, Irma; Ochoa-Rosales, Carolina; Voortman, Trudy; Ghanbari, Mohsen; van Meurs, Joyce B. J.; Nasr, Mohamed Kamal; Doerr, Marcus; Grabe, Hans J.; London, Stephanie J.; Teumer, Alexander; Waldenberger, Melanie; Weir, David R.; Smith, Jennifer A.; Levy, Daniel; Ma, Jiantao; Liu, Chunyu 分享 收藏
Association of aortic valve calcium with dementia and stroke: The Multi-Ethnic Study of Atherosclerosis 主动脉瓣钙与痴呆和中风的关系: 动脉粥样硬化的多种族研究 Marrero, Natalie; Jha, Kunal; Hughes, Timothy M.; Razavi, Alexander C.; Grant, Jelani K.; Boakye, Ellen; Anchouche, Khalil; Dzaye, Omar; Budoff, Matthew J.; Rotter, Jerome I.; Guo, Xiuqing; Yao, Jie; Wood, Alexis C.; Blumenthal, Roger S.; Michos, Erin D.; Thanassoulis, George; Post, Wendy S.; Blaha, Michael J.; Ibeh, Chinwe; Whelton, Seamus P. 分享 收藏
Predictors of incident stroke among individuals without coronary artery calcification: A pooled cohort analysis from the Multi-Ethnic Study of Atherosclerosis, Jackson Heart Study, and Framingham Heart Study Hussain, Aliza; Johansen, Michelle C.; Blaha, Michael J.; Al-Mallah, Mouaz H.; Cainzos-Achirica, Miguel; Nambi, Vijay; Rotter, Jerome, I; Guo, Xiuqing; Yao, Jie; Rich, Stephen S.; Patel, Jaideep; McEvoy, John W.; Nasir, Khurram; Gottesman, Rebecca; Blumenthal, Roger S.; Ballantyne, Christie M.; Virani, Salim S.; Al Rifai, Mahmoud 分享 收藏
Genome-Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125 393 Participants 血清钙对125 393参与者心室复极时间的全基因组相互作用分析 Young, William J.; van der Most, Peter J.; Bartz, Traci M.; Bos, Maxime M.; Biino, Ginevra; Duong, ThuyVy; Foco, Luisa; Lominchar, Jesus T.; Mueller-Nurasyid, Martina; Nardone, Giuseppe Giovanni; Pecori, Alessandro; Ramirez, Julia; Repetto, Linda; Schramm, Katharina; Shen, Xia; van Duijvenboden, Stefan; van Heemst, Diana; Weiss, Stefan; Yao, Jie; Benjamins, Jan-Walter; Alonso, Alvaro; Spedicati, Beatrice; Biggs, Mary L.; Brody, Jennifer A.; Doerr, Marcus; Fuchsberger, Christian; Goegele, Martin; Guo, Xiuqing; Ikram, M. Arfan; Jukema, J. Wouter; Kaeaeb, Stefan; Kanters, Jorgen K.; Lin, Henry J.; Linneberg, Allan; Nauck, Matthias; Nolte, Ilja M.; Pianigiani, Giulia; Santin, Aurora; Soliman, Elsayed Z.; Tesolin, Paola; Vaccargiu, Simona; Waldenberger, Melanie; van der Harst, Pim; Verweij, Niek; Arking, Dan E.; Concas, Maria Pina; De Grandi, Alessandro; Girotto, Giorgia; Grarup, Niels; Kavousi, Maryam; Mook-Kanamori, Dennis O.; Navarro, Pau; Orini, Michele; Padmanabhan, Sandosh; Pattaro, Cristian; Peters, Annette; Pirastu, Mario; Pramstaller, Peter P.; Heckbert, Susan R.; Sinner, Mortiz; Snieder, Harold; Voelker, Uwe; Wilson, James F.; Gauderman, W. James; Lambiase, Pier D.; Sotoodehnia, Nona; Tinker, Andrew; Warren, Helen R.; Noordam, Raymond; Munroe, Patricia B. 分享 收藏
Phase III study of SHR-1701 versus placebo in combination with chemo as first-line (1L) therapy for HER2-negative gastric/gastroesophageal junction adenocarcinoma (G/GEJA) SHR-1701与安慰剂联合化疗作为HER2阴性胃/胃食管结合部腺癌（G/GEJA）的一线（1L）治疗的III期研究 Peng, Z.; Wang, J.; Zhang, Y.; Li, H.; Zhao, Q.; Zhu, X.; Wei, S.; Cheng, Y.; Yang, W.; Yao, J.; Zhang, M.; Xie, L.; Zhang, X.; Zhao, P.; Hu, C.; Zhang, J.; Wang, Z.; Wang, W.; Han, H.; Shen, L. 分享 收藏
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Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People With Type 2 Diabetes 2型糖尿病患者发生心血管疾病的时间-事件全基因组关联研究 Kwak, Soo Heon; Hernandez-Cancela, Ryan B.; DiCorpo, Daniel A.; Condon, David E.; Merino, Jordi; Wu, Peitao; Brody, Jennifer A.; Yao, Jie; Guo, Xiuqing; Ahmadizar, Fariba; Meyer, Mariah; Sincan, Murat; Mercader, Josep M.; Lee, Sujin; Haessler, Jeffrey; Vy, Ha My T.; Lin, Zhaotong; Armstrong, Nicole D.; Gu, Shaopeng; Tsao, Noah L.; Lange, Leslie A.; Wang, Ningyuan; Wiggins, Kerri L.; Trompet, Stella; Liu, Simin; Loos, Ruth J. F.; Judy, Renae; Schroeder, Philip H.; Hasbani, Natalie R.; Bos, Maxime M.; Morrison, Alanna C.; Jackson, Rebecca D.; Reiner, Alexander P.; Manson, JoAnn E.; Chaudhary, Ninad S.; Carmichael, Lynn K.; Chen, Yii-Der Ida; Taylor, Kent D.; Ghanbari, Mohsen; van Meurs, Joyce; Pitsillides, Achilleas N.; Psaty, Bruce M.; Noordam, Raymond; Do, Ron; Park, Kyong Soo; Jukema, J. Wouter; Kavousi, Maryam; Correa, Adolfo; Rich, Stephen S.; Damrauer, Scott M.; Hajek, Catherine; Cho, Nam H.; Irvin, Marguerite R.; Pankow, James S.; Nadkarni, Girish N.; Sladek, Robert; Goodarzi, Mark O.; Florez, Jose C.; Chasman, Daniel I.; Heckbert, Susan R.; Kooperberg, Charles; Dupuis, Josee; Malhotra, Rajeev; de Vries, Paul S.; Liu, Ching-Ti; Rotter, Jerome I.; Meigs, James B. 分享 收藏
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Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification 全基因组测序揭示了冠状动脉钙化的两个基因座，并将ARSE鉴定为血管钙化的调节剂 de Vries, Paul S.; Conomos, Matthew P.; Singh, Kuldeep; Nicholson, Christopher J.; Jain, Deepti; Hasbani, Natalie R.; Jiang, Wanlin; Lee, Sujin; Lino Cardenas, Christian L.; Lutz, Sharon M.; Wong, Doris; Guo, Xiuqing; Yao, Jie; Young, Erica P.; Tcheandjieu, Catherine; Hilliard, Austin T.; Bis, Joshua C.; Bielak, Lawrence F.; Brown, Michael R.; Musharoff, Shaila; Clarke, Shoa L.; Terry, James G.; Palmer, Nicholette D.; Yanek, Lisa R.; Xu, Huichun; Heard-Costa, Nancy; Wessel, Jennifer; Selvaraj, Margaret Sunitha; Li, Rebecca H.; Sun, Xiao; Turner, Adam W.; Stilp, Adrienne M.; Khan, Alyna; Newman, Anne B.; Rasheed, Asif; Freedman, Barry I.; Kral, Brian G.; McHugh, Caitlin P.; Hodonsky, Chani; Saleheen, Danish; Herrington, David M.; Jacobs, David R., Jr.; Nickerson, Deborah A.; Boerwinkle, Eric; Wang, Fei Fei; Heiss, Gerardo; Jun, Goo; Kinney, Greg L.; Sigurslid, Haakon H.; Doddapaneni, Harshavardhan; Hall, Ira M.; Bensenor, Isabela M.; Broome, Jai; Crapo, James D.; Wilson, James G.; Smith, Jennifer A.; Blangero, John; Vargas, Jose D.; Mosquera, Jose Verdezoto; Smith, Joshua D.; Viaud-Martinez, Karine A.; Ryan, Kathleen A.; Young, Kendra A.; Taylor, Kent D.; Lange, Leslie A.; Emery, Leslie S.; Bittencourt, Marcio S.; Budoff, Matthew J.; Montasser, May E.; Yu, Miao; Mahaney, Michael C.; Mahamdeh, Mohammed S.; Fornage, Myriam; Franceschini, Nora; Lotufo, Paulo A.; Natarajan, Pradeep; Wong, Quenna; Mathias, Rasika A.; Gibbs, Richard A.; Do, Ron; Mehran, Roxana; Tracy, Russell P.; Kim, Ryan W.; Nelson, Sarah C.; Damrauer, Scott M.; Kardia, Sharon L. R.; Rich, Stephen S.; Fuster, Valentin; Napolioni, Valerio; Zhao, Wei; Tian, Wenjie; Yin, Xianyong; Min, Yuan-, I; Manning, Alisa K.; Peloso, Gina; Kelly, Tanika N.; O'Donnell, Christopher J.; Morrison, Alanna C.; Curran, Joanne E.; Zapol, Warren M.; Bowden, Donald W.; Becker, Lewis C.; Correa, Adolfo; Mitchell, Braxton D.; Psaty, Bruce M.; Carr, John Jeffrey; Pereira, Alexandre C.; Assimes, Themistocles L.; Stitziel, Nathan O.; Hokanson, John E.; Laurie, Cecelia A.; Rotter, Jerome I.; Vasan, Ramachandran S.; Post, Wendy S.; Peyser, Patricia A.; Miller, Clint L.; Malhotra, Rajeev 分享 收藏
The Multi-Ethnic Association of Aortic Valve Calcium and Long-Term Risk of Incident Severe Aortic Stenosis: Multi-Ethnic Study of Atherosclerosis Grant, Jelani K.; Jha, Kunal; Marrero, Natalie; Razavi, Alexander C.; Boakye, Ellen; Anchouche, Khalil; Dzaye, Omar; Budoff, Matthew; Shah, Sanjiv J.; Czarny, Matthew J.; Rotter, Jerome I.; Guo, Xiuqing; Yao, Jie; Blumenthal, Roger S.; Thanassoulis, George; Post, Wendy S.; Blaha, Michael J.; Whelton, Seamus P. 分享 收藏
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