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G

George Kunos

nih national institute on alcohol abuse & alcoholism (niaaa)

94H指数
384论文数
3.5W被引数
收录论文 161
发表时间
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Aquaporin 9 regulates acetaldehyde uptake, alcohol-induced liver injury, and drinking behavior水通道蛋白9调节乙醛摄取、酒精诱导的肝脏损伤和饮酒行为
erralcohol, clinical and experimental research
IF0
err2026-04-06
err0
PREAI
errCheng Chen; Bryan Mackowiak; Dechun Feng; Yukun Guan; Yu-hong Lin; Yaojie Fu; Shoupeng Wei; Li Zhang; George Kunos; Bin Gao
err分享
err收藏
Monlunabant in adults with obesity and metabolic syndrome: Open-label extension of a phase 2a trialMonlunabant在成人体重肥胖和代谢综合征中的研究：2a期临床试验的开放标签扩展研究
errdiabetes, obesity and metabolism
IF0
err2026-03-24
err0
errOAAI
errFilip K. Knop MD; George Kunos MD; Dror Dicker MD; Jean-Sebastien Paquette MD; Louis Aronne MD; Oscar Birkhan MD; Ofir Frenkel MD; Thomas Holst-Hansen PhD; Karine Lalonde MSc; Glenn Crater MD; for the trial investigators
err分享
err收藏
A double-blind, randomized, placebo-controlled, phase 2 trial examined the efficacy and safety of monlunabant in adults with diabetic kidney disease一项双盲、随机、安慰剂对照的2期试验，考察了monlunabant在糖尿病肾病患者中的有效性和安全性。
errKidney International
IF12.6
err2026-03-20
err0
errOAAI
errDavid Z.I. Cherney; Karen Bonefeld; Glenn Crater; Jamie P. Dwyer; Ofir Frenkel; Julie F. Furberg; Filip K. Knop; George Kunos; Karine Lalonde; David C. Wheeler; Christoph Wanner
err分享
err收藏
Hepatic Aquaporin 8 Promotes Alcohol Consumption and Ameliorates Alcohol-Induced Liver Injury by Facilitating Acetaldehyde Excretion肝水通道蛋白8通过促进乙醛排泄促进酒精摄入并改善酒精诱导的肝脏损伤
errInternational Journal of Biological Sciences
IF10
err2026-01-01
err0
PREAI
errChen, Cheng; Lin, Yu-Hong; Feng, Dechun; Guan, Yukun; Fu, Yaojie; Wang, Yang; Maccioni, Luca; Seyhan, Deniz; Yao, Tiantian; Wei, Shoupeng; Zhang, Li; Kunos, George; Mackowiak, Bryan; Gao, Bin
err分享
err收藏
Efficacy and safety of monlunabant in adults with obesity and metabolic syndrome: a double-blind, randomised, placebo-controlled, phase 2a trial莫仑那班在肥胖和代谢综合征成人中的疗效与安全性：一项双盲、随机、安慰剂对照、2a期试验
errThe Lancet Diabetes & Endocrinology
IF41.8
err2025-09-29
err0
PREAI
errFilip K Knop; George Kunos; Dror Dicker; Jean-Sebastien Paquette; Louis Aronne; Ofir Frenkel; Thomas Holst-Hansen; Karine Lalonde; Jisoo Lee; Glenn Crater
err分享
err收藏
CB1 receptors on a subset of vagal afferent neurons modulate voluntary ethanol intake in mice小鼠亚群迷走传入神经元上的CB1受体调节自愿乙醇摄入量。
errMolecular Psychiatry
IF10.1
err2025-09-20
err0
errOAAI
errAlexa Herrerias; Anna Oliverio; Szabolcs Dvorácskó; Arthi Thyagarajan; Lee Chedester; Jie Liu; Resat Cinar; Malliga R. Iyer; George Kunos; Grzegorz Godlewski
err分享
err收藏
Hepatic CB1 receptor signaling triggers Gi/oα-mediated lipolysis in lean mice but Gsα-mediated lipogenesis in obese mice肝源性CB1受体信号在瘦小鼠中触发Gi/oα介导的脂肪分解，但在肥胖小鼠中触发Gsα介导的脂肪生成。
errMetabolism
IF0
err2025-05-28
err0
errOAAI
errJie Liu; Anna Oliverio; Grzegorz Godlewski; Radka Kočvarová; Muhammad Arif; Abhishek Basu; Yukun Guan; Dechun Feng; Henry L. Puhl; Malliga R. Iyer; Resat Cinar; Bin Gao; Joseph Tam; George Kunos
err分享
err收藏
Opposite regulation of intestinal and intrahepatic CD8+ T cells controls alcohol-associated liver disease progression肠内和肝内CD8+ T细胞的反向调控控制酒精相关肝病进展
errGUT
IF25.8
err2025-04-08
err2
PREAI
errMaccioni, Luca; Guan, Yukun; Kim, Mariia; Parra, Maria A.; Peiffer, Brandon; Fu, Yaojie; Wang, Yang; Lin, Yu-Hong; Mackowiak, Bryan; Feng, Dechun; Cameron, Andrew; Sun, Zhaoli; Kunos, George; Starkel, Peter; Gao, Bin
err分享
err收藏
Structural mechanism of CB1R binding to peripheral and biased inverse agonists
errNATURE COMMUNICATIONS
IF15.7
err2024-12-18
err0
errOAAI
errKumari, Punita; Dvoracsko, Szabolcs; Enos, Michael D.; Ramesh, Karthik; Lim, Darrix; Hassan, Sergio A.; Kunos, George; Cinar, Resat; Iyer, Malliga R.; Rosenbaum, Daniel M.
err分享
err收藏
Coordinated action of a gut-liver pathway drives alcohol detoxification and consumption
errNATURE METABOLISM
IF20.8
err2024-06-20
err7
PREAI
errFu, Yaojie; Mackowiak, Bryan; Lin, Yu-Hong; Maccioni, Luca; Lehner, Taylor; Pan, Hongna; Guan, Yukun; Godlewski, Grzegorz; Lu, Hongkun; Chen, Cheng; Wei, Shoupeng; Feng, Dechun; Paloczi, Janos; Zhou, Huiping; Pacher, Pal; Zhang, Li; Kunos, George; Gao, Bin
err分享
err收藏
A patient-based iPSC-derived hepatocyte model of alcohol-associated cirrhosis reveals bioenergetic insights into disease pathogenesis
errNATURE COMMUNICATIONS
IF15.7
err2024-05-01
err2
errOAAI
errMukhopadhyay, Bani; Marietta, Cheryl; Shen, Pei-Hong; Oiseni, Abdul; Mirshahi, Faridoddin; Mazzu, Maria; Hodgkinson, Colin; Winkler, Eli; Yuan, Qiaoping; Miranda, Daniel; Kunos, George; Sanyal, Arun J.; Goldman, David
err分享
err收藏
In vitro and in vivo pharmacokinetic characterization, chiral conversion and PBPK scaling towards human PK simulation of S-MRI-1867, a drug candidate for Hermansky-Pudlak syndrome pulmonary fibrosisHermansky-pudlak综合征肺纤维化的候选药物S-MRI-1867的体外和体内药代动力学表征，手性转化和PBPK缩放
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2023-12-01
err1
errOAAI
errPadilha, Elias C.; Yang, Mengbi; Shah, Pranav; Wang, Amy Q.; Duan, Jianmin; Park, Joshua K.; Zawatsky, Charles N.; Malicdan, May Christine V.; Kunos, George; Iyer, Malliga R.; Gaucher, Genevieve; Ravenelle, Francois; Cinar, Resat; Xu, Xin
err分享
err收藏
A cortico-amygdala neural substrate for endocannabinoid modulation of fear extinction
errNEURON
IF15
err2023-10-01
err14
errOAAI
errGunduz-Cinar, Ozge; Castillo, Laura I.; Xia, Maya; Van Leer, Elise; Brockway, Emma T.; Pollack, Gabrielle A.; Yasmin, Farhana; Bukalo, Olena; Limoges, Aaron; Oreizi-Esfahani, Sarvar; Kondev, Veronika; Baldi, Rita; Dong, Ao; Harvey-White, Judy; Cinar, Resat; Kunos, George; Li, Yulong; Zweifel, Larry S.; Patel, Sachin; Holmes, Andrew
err分享
err收藏
Monocyte-derived macrophages orchestrate multiple cell-type interactions to repair necrotic liver lesions in disease models
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2023-08-01
err24
errOAAI
errFeng, Dechun; Xiang, Xiaogang; Guan, Yukun; Guillot, Adrien; Lu, Hongkun; Chang, Chingwen; He, Yong; Wang, Hua; Pan, Hongna; Ju, Cynthia; Colgan, Sean P.; Tacke, Frank; Wang, Xin Wei; Kunos, George; Gao, Bin
err分享
err收藏
A human laboratory study on the link between alcohol administration and circulating fibroblast growth factor 21 (FGF21) in individuals with alcohol use disorder
errDRUG AND ALCOHOL DEPENDENCE
IF3.6
err2023-04-01
err4
PREAI
errFarokhnia, Mehdi; Wang, Tammy; Jourdan, Tony; Godlewski, Grzegorz; Farinelli, Lisa A.; Kunos, George; Leggio, Lorenzo
err分享
err收藏
Differential regulation of the mitogen-activated protein and stress-activated protein kinase cascades by adrenergic agonists in quiescent and regenerating adult rat hepatocytes
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-29
err104
errOAAI
errSpector, MS; Auer, KL; Jarvis, WD; Ishac, EJN; Gao, B; Kunos, G; Dent, P
err分享
err收藏
The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics
errCELL DEATH DISCOVERY
IF7
err2023-03-25
err4
errOAAI
errMukhopadhyay, Bani; Holovac, Kellie; Schuebel, Kornel; Mukhopadhyay, Partha; Cinar, Resat; Iyer, Sindhu; Marietta, Cheryl; Goldman, David; Kunos, George
err分享
err收藏
The effects of acute alcohol administration on circulating endocannabinoid levels in humans
errADDICTION BIOLOGY
IF2.6
err2022-06-29
err0
errOAAI
errSloan, Matthew E.; Grant, Caroline W.; Stangl, Bethany L.; Klepp, Timothy D.; Brewton, Honoree W.; Cinar, Resat; Kunos, George; Ramchandani, Vijay A.
err分享
err收藏
Do endocannabinoids acting via hepatic CB-1 contribute to NAFLD and hepatic insulin resistance?
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2022-01-04
err1
errOAAI
errKunos, George; Jourdan, Tony; Tam, Joseph
err分享
err收藏
Peripheral Hybrid CB1R and iNOS Antagonist MRI-1867 Displays Anti-Fibrotic Efficacy in Bleomycin-Induced Skin Fibrosis
errFRONTIERS IN ENDOCRINOLOGY
IF4.6
err2021-09-28
err11
errOAAI
errZawatsky, Charles N.; Park, Joshua K.; Abdalla, Jasmina; Kunos, George; Iyer, Malliga R.; Cinar, Resat
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
T
Terrie E. Moffitt
H 指数: 215 · 论文数: 922
M
M Snyder
H 指数: 210 · 论文数: 3.3K
M
Marc G. Caron
H 指数: 175 · 论文数: 810
N
Nora D. Volkow
H 指数: 170 · 论文数: 1.3K
A
Arun J. Sanyal
H 指数: 166 · 论文数: 1.4K
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