Guy A. Higgins - Publications, H-index & Citations

Guy A. Higgins

transpharmation inc., fergus, on, canada

66H指数

178论文数

1.1W被引数

收录论文 65

发表时间

Pharmacological characterisation of psilocybin and 5-MeO-DMT discriminative cues in the rat and their translational value for identifying novel psychedelics 致幻剂psilocybin和5-MeO-DMT在 rats 中的药理学表征及其在识别新型致幻剂方面的转化价值

Journal of Psychopharmacology

IF5.5

2025-08-27

OAAI

Guy A Higgins; Cam MacMillan; Ines de Lannoy; Carolyn Tyler; Malik Slassi

Contrasting effects of d-amphetamine and atomoxetine on measures of impulsive action and choice

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

IF2.5

2021-08-01

PREAI

Higgins, Guy A.; Brown, Matt; MacMillan, Cam; Silenieks, Leo B.; Thevarkunnel, Sandy

Lorcaserin: A review of its preclinical and clinical pharmacology and therapeutic potential

PHARMACOLOGY & THERAPEUTICS

IF12.5

2020-01-01

PREAI

Higgins, Guy A.; Fletcher, Paul J.; Shanahan, William R.

Evaluation of Selective 5-HT2C Agonists in Acute Seizure Models

ACS CHEMICAL NEUROSCIENCE

IF3.9

2019-05-13

PREAI

Silenieks, Leonardo B.; Carroll, Nicole K.; Van Niekerk, Annalise; Van Niekerk, Emily; Taylor, Colleen; Upton, Neil; Higgins, Guy A.

Preclinical evidence for combining the 5-HT2C receptor agonist lorcaserin and varenicline as a treatment for nicotine dependence

ADDICTION BIOLOGY

IF2.6

2018-03-02

PREAI

Fletcher, Paul J.; Li, Zhaoxia; Silenieks, Leo B.; MacMillan, Cam; DeLannoy, Ines; Higgins, Guy A.

Pharmacological Modulation of 5-HT2C Receptor Activity Produces Bidirectional Changes in Locomotor Activity, Responding for a Conditioned Reinforcer, and Mesolimbic DA Release in C57BL/6 Mice

NEUROPSYCHOPHARMACOLOGY

IF7.1

2017-06-13

OAAI

Browne, Caleb J.; Ji, Xiaodong; Higgins, Guy A.; Fletcher, Paul J.; Harvey-Lewis, Colin

18F-FPP: A PET Ligand for the 5-HT2C Receptor?

ACS CHEMICAL NEUROSCIENCE

IF3.9

2017-05-01

PREAI

Higgins, Guy A.

Studies To Examine Potential Tolerability Differences between the 5-HT2C Receptor Selective Agonists Lorcaserin and CP-809101

ACS CHEMICAL NEUROSCIENCE

IF3.9

2017-03-24

PREAI

Higgins, Guy A.; Silenieks, Leonardo B.; Patrick, Amy; De Lannoy, Ines A. M.; Fletcher, Paul J.; Parker, Linda A.; MacLusky, Neil J.; Sullivan, Laura C.; Chavera, Teresa A.; Berg, Kelly A.

Effects of 5-HT1A, 5-HT2A and 5-HT2C receptor agonists and antagonists on responding for a conditioned reinforcer and its enhancement by methylphenidate 5-HT1A，5-HT2A和5-HT2C受体激动剂和拮抗剂对条件性增强剂的反应及其对哌醋甲酯的增强作用的影响

PSYCHOPHARMACOLOGY

IF3.3

2017-01-18

PREAI

Fletcher, Paul J.; Zeeb, Fiona D.; Browne, Caleb J.; Higgins, Guy A.; Soko, Ashlie D.

Lorcaserin and CP-809101 reduce motor impulsivity and reinstatement of food seeking behavior in male rats: Implications for understanding the anti-obesity property of 5-HT2C receptor agonists

PSYCHOPHARMACOLOGY

IF3.3

2016-05-30

PREAI

Higgins, Guy A.; Silenieks, Leo B.; Altherr, Everett B.; MacMillan, Cam; Fletcher, Paul J.; Pratt, Wayne E.

Therapeutic Potential of 5-HT2C Receptor Agonists for Addictive Disorders

ACS CHEMICAL NEUROSCIENCE

IF3.9

2015-04-14

PREAI

Higgins, Guy A.; Fletcher, Paul J.

The Serotonin 2C Receptor Agonist Lorcaserin Attenuates Intracranial Self-Stimulation and Blocks the Reward-Enhancing Effects of Nicotine 5-羟色胺2C受体激动剂Lorcaserin减弱颅内自我刺激并阻断尼古丁的奖励增强作用

ACS CHEMICAL NEUROSCIENCE

IF3.9

2015-03-17

PREAI

Zeeb, Fiona D.; Higgins, Guy A.; Fletcher, Paul J.

From obesity to substance abuse: therapeutic opportunities for 5-HT2C receptor agonists

TRENDS IN PHARMACOLOGICAL SCIENCES

IF19.9

2013-10-01

PREAI

Higgins, Guy A.; Sellers, Edward M.; Fletcher, Paul J.

Silexan, an essential oil from flowers of Lavandula angustifolia, is not recognized as benzodiazepine-like in rats trained to discriminate a diazepam cue

PHYTOMEDICINE

IF8.3

2013-01-01

PREAI

Silenieks, Leo B.; Koch, Egon; Higgins, Guy A.

Impulsive action in the 5-choice serial reaction time test in 5-HT2C receptor null mutant mice

PSYCHOPHARMACOLOGY

IF3.3

2012-11-29

PREAI

Fletcher, Paul J.; Soko, Ashlie D.; Higgins, Guy A.

Evaluation of chemically diverse 5-HT2C receptor agonists on behaviours motivated by food and nicotine and on side effect profiles

PSYCHOPHARMACOLOGY

IF3.3

2012-11-25

PREAI

Higgins, G. A.; Silenieks, L. B.; Lau, W.; de Lannoy, I. A. M.; Lee, D. K. H.; Izhakova, J.; Coen, K.; Le, A. D.; Fletcher, P. J.

Rolapitant (SCH 619734): A potent, selective and orally active neurokinin NK1 receptor antagonist with centrally-mediated antiemetic effects in ferrets 罗拉吡坦 (SCH 619734): 一种有效，选择性和口服活性的神经激肽NK1受体拮抗剂，在雪貂中具有中枢介导的止吐作用

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

IF2.5

2012-07-01

PREAI

Duffy, Ruth A.; Morgan, Cynthia; Naylor, Robert; Higgins, Guy A.; Varty, Geoffrey B.; Lachowicz, Jean E.; Parker, Eric M.

The 5-HT2C Receptor Agonist Lorcaserin Reduces Nicotine Self-Administration, Discrimination, and Reinstatement: Relationship to Feeding Behavior and Impulse Control

NEUROPSYCHOPHARMACOLOGY

IF7.1

2011-12-21

129

OAAI

Higgins, Guy A.; Silenieks, Leo B.; Rossmann, Anne; Rizos, Zoe; Noble, Kevin; Soko, Ashlie D.; Fletcher, Paul J.

The anxiolytic-like profile of the nociceptin receptor agonist, endo-8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1] octane-3-carboxamide (SCH 655842): Comparison of efficacy and side effects across rodent species

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2011-07-01

PREAI

Lu, Sherry X.; Higgins, Guy A.; Hodgson, Robert A.; Hyde, Lynn A.; Del Vecchio, Robert A.; Guthrie, Donald H.; Kazdoba, Tatiana; McCool, Martha F.; Morgan, Cynthia A.; Bercovici, Ana; Ho, Ginny D.; Tulshian, Deen; Parker, Eric M.; Hunter, John C.; Varty, Geoffrey B.

Genetic and pharmacological evidence that 5-HT2C receptor activation, but not inhibition, affects motivation to feed under a progressive ratio schedule of reinforcement

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

IF2.5

2010-11-01

PREAI

Fletcher, Paul J.; Sinyard, Judy; Higgins, Guy A.

研究方向