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收藏分享 收藏 分享 收藏 分享 收藏 Recessive TMEM167A variants cause neonatal diabetes, microcephaly, and epilepsy syndrome
Virgilio, Enrico; Tielens, Sylvia; Bonfield, Georgia; Nian, Fang-Shin; Sawatani, Toshiaki; Vinci, Chiara; Govier, Molly; Montaser, Hossam; Lartigue, Romane; Arunagiri, Anoop; Liboz, Alexandrine; Da Silva, Flavia Natividade; Lytrivi, Maria; Papadopoulou, Theodora; Wakeling, Matthew N.; Russ-Silsby, James; Bowman, Pamela; Johnson, Matthew B.; Laver, Thomas W.; Piron, Anthony; Yi, Xiaoyan; Fantuzzi, Federica; Hendrickx, Sirine; Igoillo-Esteve, Mariana; Santacreu, Bruno J.; Suntharesan, Jananie; Ghildiyal, Radha; Hegde, Darshan; Shah, Nikhil; Acar, Sezer; Donmez, Beyhan Ozkaya; Ozkan, Behzat; Mohsin, Fauzia; Talaat, Iman M.; Abbas, Mohamed Tarek; Abbas, Omar Tarek; Alghamdi, Hamed Ali; Kandemir, Nurgun; Flanagan, Sarah E.; Scharfmann, Raphael; Arvan, Peter; Raoux, Matthieu; Nguyen, Laurent; Hattersley, Andrew T.; Cnop, Miriam; De Franco, Elisa 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Functional genetics reveals the contribution of delta opioid receptor to type 2 diabetes and beta-cell functionMeulebrouck, Sarah; Merrheim, Judith; Queniat, Gurvan; Bourouh, Cyril; Derhourhi, Mehdi; Boissel, Mathilde; Yi, Xiaoyan; Badreddine, Alaa; Boutry, Raphael; Leloire, Audrey; Toussaint, Benedicte; Amanzougarene, Souhila; Vaillant, Emmanuel; Durand, Emmanuelle; Loiselle, Helene; Huyvaert, Marlene; Dechaume, Aurelie; Scherrer, Victoria; Marchetti, Piero; Balkau, Beverley; Charpentier, Guillaume; Franc, Sylvia; Marre, Michel; Roussel, Ronan; Scharfmann, Raphael; Cnop, Miriam; Canouil, Mickael; Baron, Morgane; Froguel, Philippe; Bonnefond, Amelie 分享 收藏 A 3D atlas of the human developing pancreas to explore progenitor proliferation and differentiationVillalba, Adrian; Gitton, Yorick; Inoue, Megumi; Aiello, Virginie; Blain, Raphael; Toupin, Maryne; Mazaud-Guittot, Severine; Rachdi, Latif; Semb, Henrik; Chedotal, Alain; Scharfmann, Raphael 分享 收藏 LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic βcellsLDHB有助于调节人胰腺 β 细胞的乳酸水平和基础胰岛素分泌Cuozzo, Federica; Viloria, Katrina; Shilleh, Ali H.; Nasteska, Daniela; Frazer-Morris, Charlotte; Tong, Jason; Jiao, Zicong; Boufersaoui, Adam; Marzullo, Bryan; Rosoff, Daniel B.; Smith, Hannah R.; Bonner, Caroline; Kerr-Conte, Julie; Pattou, Francois; Nano, Rita; Piemonti, Lorenzo; Johnson, Paul R. V.; Spiers, Rebecca; Roberts, Jennie; Lavery, Gareth G.; Clark, Anne; Ceresa, Carlo D. L.; Ray, David W.; Hodson, Leanne; Davies, Amy P.; Rutter, Guy A.; Oshima, Masaya; Scharfmann, Raphael; Merrins, Matthew J.; Akerman, Ildem; Tennant, Daniel A.; Ludwig, Christian; Hodson, David J. 分享 收藏 Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8+ T cell responsesVecchio, Federica; Carre, Alexia; Korenkov, Daniil; Zhou, Zhicheng; Apaolaza, Paola; Tuomela, Soile; Burgos-Morales, Orlando; Snowhite, Isaac; Perez-Hernandez, Javier; Brandao, Barbara; Afonso, Georgia; Halliez, Clementine; Kaddis, John; Kent, Sally C.; Nakayama, Maki; Richardson, Sarah J.; Vinh, Joelle; Verdier, Yann; Laiho, Jutta; Scharfmann, Raphael; Solimena, Michele; Marinicova, Zuzana; Bismuth, Elise; Lucidarme, Nadine; Sanchez, Janine; Bustamante, Carmen; Gomez, Patricia; Buus, Soren; You, Sylvaine; Pugliese, Alberto; Hyoty, Heikki; Rodriguez-Calvo, Teresa; Flodstrom-Tullberg, Malin; Mallone, Roberto 分享 收藏 EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretionEndoC-βH5细胞是具有生理性胰岛素分泌的可储存和即用型人胰腺 β 细胞Blanchi, Bruno; Taurand, Marion; Colace, Claire; Thomaidou, Sofia; Audeoud, Charlotte; Fantuzzi, Federica; Sawatani, Toshiaki; Gheibi, Sevda; Sabadell-Basallote, Joan; Boot, Fransje W. J.; Chantier, Thibault; Piet, Aline; Cavanihac, Charlotte; Pilette, Marion; Balguerie, Adelie; Olleik, Hamza; Carlotti, Francoise; Ejarque, Miriam; Fex, Malin; Mulder, Hindrik; Cnop, Miriam; Eizirik, Decio L.; Jouannot, Ouardane; Gaffuri, Anne-Lise; Czernichow, Paul; Zaldumbide, Arnaud; Scharfmann, Raphael; Ravassard, Philippe 分享 收藏 Human GLP1R variants affecting GLP1R cell surface expression are associated with impaired glucose control and increased adiposityGao, Wenwen; Liu, Lei; Huh, Eunna; Gbahou, Florence; Cecon, Erika; Oshima, Masaya; Houze, Ludivine; Katsonis, Panagiotis; Hegron, Alan; Fan, Zhiran; Hou, Guofei; Charpentier, Guillaume; Boissel, Mathilde; Derhourhi, Mehdi; Marre, Michel; Balkau, Beverley; Froguel, Philippe; Scharfmann, Raphael; Lichtarge, Olivier; Dam, Julie; Bonnefond, Amelie; Liu, Jianfeng; Jockers, Ralf 分享 收藏 Tryptophan metabolism promotes immune evasion in human pancreatic cellsRachdi, Latif; Zhou, Zhicheng; Berthault, Claire; Lourenco, Chloe; Fouque, Alexis; Domet, Thomas; Armanet, Mathieu; You, Sylvaine; Peakman, Mark; Mallone, Roberto; Scharfmann, Raphael 分享 收藏 分享 收藏 Pancreatic Islet Cells Response to IFNγ Relies on Their Spatial Location within an Islet胰岛细胞对ifn γ 的反应依赖于它们在胰岛内的空间位置De Burghgrave, Marine; Lourenco, Chloe; Berthault, Claire; Aiello, Virginie; Villalba, Adrian; Fouque, Alexis; Diedisheim, Marc; You, Sylvaine; Oshima, Masaya; Scharfmann, Raphael 分享 收藏 分享 收藏 Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intracellular and extracellular regulatory circuitsSaitoski, Kevin; Ryaboshapkina, Maria; Hamza, Ghaith M.; Jarnuczak, Andrew F.; Berthault, Claire; Carlotti, Francoise; Armanet, Mathieu; Sengupta, Kaushik; Underwood, Christina Rye; Andersson, Shalini; Guillas, Isabelle; Le Goff, Wilfried; Scharfmann, Raphael 分享 收藏 
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