David E. Gloriam - Publications, H-index & Citations

David E. Gloriam

communaute universite grenoble alpes

48H指数

157论文数

1.4W被引数

收录论文 88

发表时间

International Union of Basic and Clinical Pharmacology xxx: Applying an objective evaluation to the status of Class A orphan G protein-coupled receptors 国际基本与临床药理学学会XXX：对A类孤儿G蛋白偶联受体状态进行客观评估

Pharmacological Reviews

IF17.3

2026-05-08

OAAI

Stephen P.H. Alexander; Kirstie A. Bennett; Andrew J. Brown; Michelle Glass; David E. Gloriam; Julien Hanson; Paul A. Insel; Eamonn Kelly; Christopher J. Langmead; Kirill A. Martemyanov; Rick R. Neubig; Stefan Offermanns; Mette M. Rosenkilde; Gunnar Schulte; Nicola J. Smith; Huixian Wu; Elena Faccenda; Simon D. Harding; Anthony P. Davenport

The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors 《简明药理学指南2025/26：G蛋白偶联受体》

British Journal of Pharmacology

IF7.7

2025-12-01

OAAI

Alexander, Stephen P. H.; Davenport, Anthony P.; Kelly, Eamonn; Gibb, Alasdair J.; Mathie, Alistair A.; Peach, Chloe J.; Veale, Emma L.; Armstrong, Jane F.; Faccenda, Elena; Harding, Simon D.; Southan, Christopher; Davies, Jamie A.; Abbracchio, Maria Pia; Abraham, George R.; Agoulnik, Alexander; Alexander, Wayne; Al-hosaini, Khaled; Back, Magnus; Baker, Jillian G.; Barnes, Nicholas M.; Bathgate, Ross; Beaulieu, Jean-Martin; Beck-Sickinger, Annette G.; Behrens, Maik; Bennett, Kirstie A.; Bernstein, Kenneth E.; Bettler, Bernhard; Birdsall, Nigel J. M.; Blaho, Victoria A.; Bonaventure, Pascal; Boulay, Francois; Bousquet, Corinne; Brauner-Osborne, Hans; Brown, Andrew J.; Burnstock, Geoffrey; Busnelli, Marta; Calo, Girolamo; Caruso, Vanni; Castano, Justo P.; Catt, Kevin J.; Ceruti, Stefania; Chazot, Paul; Chiang, Nan; Chini, Bice; Christopoulos, Arthur; Chun, Jerold; Cianciulli, Antonia; Civelli, Olivier; Clapp, Lucie H.; Couture, Rejean; Cox, Helen M.; Csaba, Zsolt; Dahlgren, Claes; Dautzenberg, Frank M.; Dent, Gordon; Douglas, Steven D.; Dournaud, Pascal; Dubocovich, Margarita L.; Eguchi, Satoru; Escher, Emanuel; Filardo, Edward J.; Fong, Tung; Forsman, Huamei Fu; Fumagalli, Marta; Gainetdinov, Raul R.; Garelja, Michael L.; de Gasparo, Marc; Gbahou, Florence; Gerard, Craig; Gershengorn, Marvin; Glass, Michelle; Gloriam, David E.; Gobeil, Fernand; Goodfriend, Theodore L.; Goudet, Cyril; Gratz, Lukas; Gregory, Karen J.; Gruber, Christian; Gundlach, Andrew L.; Hamann, Jorg; Hanson, Julien; Hartman, Deborah S.; Hauger, Richard L.; Hay, Debbie L.; Heinemann, Akos; Heitman, Laura; Herr, Deron R.; Hollenberg, Morley D.; Holliday, Nicholas D.; Holst, Birgitte; Horiuchi, Mastgugu; Hoyer, Daniel; Hunyady, Laszlo; Husain, Ahsan; IJzerman, Adriaan P.; Inagami, Tadashi; Insel, Paul A.; Jacobson, Kenneth A.; Jacobson, Laura H.; Jensen, Robert T.; Jockers, Ralf; Jonnalagadda, Deepa; Karnik, Sadashiva; Kaupmann, Klemens; Kemp, Jacqueline; Kennedy, Charles; Kihara, Yasuyuki; Kinsolving, Julia; Kitazawa, Takio; Kozielewicz, Pawel; Kreienkamp, Hans-Juergen; Kukkonen, Jyrki P.; Laishram, Luxmichan; Langenhan, Tobias; Langmead, Christopher J.; Larhammar, Dan; Leach, Katie; Lecca, Davide; Lee, John D.; Leeman, Susan E.; Leprince, Jerome; Leurs, Rob; Li, Xaria X.; Liebscher, Ines; Lolait, Stephen J.; Lupp, Amelie; Macrae, Robyn; Maguire, Janet J.; Malfacini, Davide; Manning, Maurice; Marangon, Davide; Martemyanov, Kirill; Mazella, Jean; McArdle, Craig A.; Melmed, Shlomo; Michel, Martin C.; Miller, Laurence J.; Mitolo, Vincenzo; Mouillac, Bernard; Mueller, Christa E.; Murphy, Philip M.; Nahon, Jean-Louis; Neubig, Richard R.; Ngo, Tony; Norel, Xavier; Nyimanu, Duuamene; O'Carroll, Anne-Marie; Offermanns, Stefan; Panaro, Maria Antonietta; Parmentier, Marc; Perry-Hauser, Nicole; Pertwee, Roger G.; Pin, Jean-Philippe; Prossnitz, Eric R.; Qin, Helena Chengxue; Quinn, Mark; Raffaele, Stefano; Ramachandran, Rithwik; Ray, Manisha; Reinscheid, Rainer K.; Buzon, Alejandro Romeral; Rondard, Philippe; Rosenkilde, Mette M.; Rovati, G. Enrico; Ruzza, Chiara; Sanger, Gareth J.; Scholz, Nicole; Schoeneberg, Torsten; Schulte, Gunnar; Schulz, Stefan; Segaloff, Deborah L.; Serhan, Charles N.; Shukla, Arun K.; Singh, Khuraijam Dhanachandra; Smith, Craig M.; Smith, Nicola J.; Staeubert, Claudia; Stoddart, Leigh A.; Sugimoto, Yukihiko; Summers, Roger; Tan, Valerie P.; Thal, David M.; Thomas, Walter (Wally); Timmermans, Pieter B. M. W. M.; Tirupula, Kalyan; Toll, Lawrence; Tulipano, Giovanni; Unal, Hamiyet; Unger, Thomas; Valant, Celine; Vanderheyden, Patrick; Vaudry, David; Vaudry, Hubert; Verbalis, Joseph G.; Vilardaga, Jean-Pierre; Walker, Christopher S.; Wang, Ji Ming; Ward, Donald T.; Wester, Hans-Juergen; Willars, Gary B.; Williams, Tom Lloyd; Woodruff, Trent M.; Wu, Huixian; Yang, Cheng; Yao, Chengcan; Ye, Richard D.; Zaidman, Nathan

The polypharmacology of psychedelics reveals multiple targets for potential therapeutics 致幻剂的药物多效性揭示了潜在治疗药物的多重靶点

Neuron

IF15

2025-07-18

PREAI

Manish K. Jain; Ryan H. Gumpper; Samuel T. Slocum; Gavin P. Schmitz; Jakob S. Madsen; Tia A. Tummino; Carl-Mikael Suomivuori; Xi-Ping Huang; Laura Shub; Jeffrey F. DiBerto; Kuglae Kim; Chelsea DeLeon; Brain E. Krumm; Jonathan F. Fay; Michael Keiser; Alexander S. Hauser; Ron O. Dror; Brian Shoichet; David E. Gloriam; David E. Nichols; Bryan L. Roth

PGxDB: an interactive web-platform for pharmacogenomics research

NUCLEIC ACIDS RESEARCH

IF13.1

2024-11-20

OAAI

Nguyen, Trinh Trung Duong; Tanoli, Ziaurrehman; Hassan, Saad; Ozcan, Umut Onur; Caroli, Jimmy; Kooistra, Albert J.; Gloriam, David E.; Hauser, Alexander S.

GPCRdb in 2025: adding odorant receptors, data mapper, structure similarity search and models of physiological ligand complexes GPCRdb 2025年: 添加气味受体，数据映射器，结构相似性搜索和生理配体复合物模型

NUCLEIC ACIDS RESEARCH

IF13.1

2024-11-18

OAAI

Herrera, Luis P. Taracena; Andreassen, Soren N.; Caroli, Jimmy; Rodriguez-Espigares, Ismael; Kermani, Ali A.; Keseru, Gyorgy M.; Kooistra, Albert J.; Pandy-Szekeres, Gaspar; Gloriam, David E.

Differential G protein activation by the long and short isoforms of the dopamine D2 receptor 多巴胺D2受体的长短同工型的差异g蛋白激活

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2024-05-09

OAAI

Reiner-Link, David; Madsen, Jakob Sture; Gloriam, David E.; Brauner-Osborne, Hans; Hauser, Alexander S.

Ligand selectivity hotspots in serotonin GPCRs

TRENDS IN PHARMACOLOGICAL SCIENCES

IF19.9

2023-12-01

OAAI

Simon, Icaro A.; Bjorn-Yoshimoto, Walden E.; Harpsoe, Kasper; Iliadis, Stylianos; Svensson, Bo; Jensen, Anders A.; Gloriam, David E.

GproteinDb in 2024: new G protein-GPCR couplings, AlphaFold2-multimer models and interface interactions

NUCLEIC ACIDS RESEARCH

IF13.1

2023-11-24

OAAI

Pandy-Szekeres, Gaspar; Herrera, Luis P. Taracena; Caroli, Jimmy; Kermani, Ali A.; Kulkarni, Yashraj; Keseru, Gyorgy M.; Gloriam, David E.

Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformations

NATURE COMMUNICATIONS

IF15.7

2023-07-29

OAAI

Gratz, Lukas; Kowalski-Jahn, Maria; Scharf, Magdalena M.; Kozielewicz, Pawel; Jahn, Michael; Bous, Julien; Lambert, Nevin A.; Gloriam, David E.; Schulte, Gunnar

Structure-Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT2A Receptor Agonists 一组苯烷基胺5-HT2A受体激动剂的结构活性评估和偏激动作用的深入分析

ACS CHEMICAL NEUROSCIENCE

IF3.9

2023-07-20

OAAI

Pottie, Eline; Poulie, Christian B. M.; Simon, Icaro A.; Harpsoe, Kasper; D'Andrea, Laura; Komarov, Igor V.; Gloriam, David E.; Jensen, Anders A.; Kristensen, Jesper L.; Stove, Christophe P.

A community Biased Signaling Atlas

NATURE CHEMICAL BIOLOGY

IF13.7

2023-03-27

PREAI

Caroli, Jimmy; Mamyrbekov, Alibek; Harpsoe, Kasper; Gardizi, Sahar; Doerries, Linda; Ghosh, Eshan; Hauser, Alexander S.; Kooistra, Albert J.; Gloriam, David E.

Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor GPR139

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2023-03-01

OAAI

Pallareti, Lisa; Rath, Tine F.; Trapkov, Boris; Tsonkov, Tsonko; Nielsen, Anders Thorup; Harpsoe, Kasper; Gentry, Patrick R.; Brauner-Osborne, Hans; Gloriam, David E.; Foster, Simon R.

Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-02-07

PREAI

Bartling, Christian R. O.; Alexopoulou, Flora; Kuschert, Sarah; Chin, Yanni K. -Y.; Jia, Xinying; Sereikaite, Vita; Ozcelik, Dennis; Jensen, Thomas M.; Jain, Palash; Nygaard, Mads M.; Harpsoe, Kasper; Gloriam, David E.; Mobli, Mehdi; Stromgaard, Kristian

Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity

NATURE COMMUNICATIONS

IF15.7

2022-12-02

OAAI

Sandhu, Manbir; Cho, Aaron; Ma, Ning; Mukhaleva, Elizaveta; Namkung, Yoon; Lee, Sangbae; Ghosh, Soumadwip; Lee, John H.; Gloriam, David E.; Laporte, Stephane A.; Babu, M. Madan; Vaidehi, Nagarajan

GPCRdb in 2023: state-specific structure models using AlphaFold2 and new ligand resources

NUCLEIC ACIDS RESEARCH

IF13.1

2022-11-18

OAAI

Pandy-Szekeres, Gaspar; Caroli, Jimmy; Mamyrbekov, Alibek; Kermani, Ali A.; Keseru, Gyorgy M.; Kooistra, Albert J.; Gloriam, David E.

Discovery of ß-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-09-13

OAAI

Poulie, Christian B. M.; Pottie, Eline; Simon, Icaro A.; Harpsoe, Kasper; D'Andrea, Laura; Komarov, Igor V.; Gloriam, David E.; Jensen, Anders A.; Stove, Christophe P.; Kristensen, Jesper L.

GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors 5-羟色胺受体的结构揭示了gpcr通过TM5-TM6开关控制Gi和Gs选择性

MOLECULAR CELL

IF16.6

2022-07-01

OAAI

Huang, Sijie; Xu, Peiyu; Shen, Dan-Dan; Simon, Icaro A.; Mao, Chunyou; Tan, Yangxia; Zhang, Huibing; Harpsoe, Kasper; Li, Huadong; Zhang, Yumu; You, Chongzhao; Yu, Xuekui; Jiang, Yi; Zhang, Yan; Gloriam, David E.; Xu, H. Eric

Community guidelines for GPCR ligand bias: IUPHAR review 32 GPCR配体偏倚的社区指南: IUPHAR综述32

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2022-03-27

101

OAAI

Kolb, Peter; Kenakin, Terry; Alexander, Stephen P. H.; Bermudez, Marcel; Bohn, Laura M.; Breinholt, Christian S.; Bouvier, Michel; Hill, Stephen J.; Kostenis, Evi; Martemyanov, Kirill A.; Neubig, Rick R.; Onaran, H. Ongun; Rajagopal, Sudarshan; Roth, Bryan L.; Selent, Jana; Shukla, Arun K.; Sommer, Martha E.; Gloriam, David E.

Common coupling map advances GPCR-G protein selectivity 共同的耦合图提高了GPCR-g蛋白的选择性

ELIFE

IF0

2022-03-18

OAAI

Hauser, Alexander S.; Avet, Charlotte; Normand, Claire; Mancini, Arturo; Inoue, Asuka; Bouvier, Michel; Gloriam, David E.

Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs 效应膜易位生物传感器揭示了100治疗相关gpcr的g蛋白和 β 抑制蛋白偶联谱

ELIFE

IF0

2022-03-18

132

OAAI

Avet, Charlotte; Mancini, Arturo; Breton, Billy; Le Gouill, Christian; Hauser, Alexander S.; Normand, Claire; Kobayashi, Hiroyuki; Gross, Florence; Hogue, Mireille; Lukasheva, Viktoriya; St-Onge, Stephane; Carrier, Marilyn; Heroux, Madeleine; Morissette, Sandra; Fauman, Eric B.; Fortin, Jean-Philippe; Schann, Stephan; Leroy, Xavier; Gloriam, David E.; Bouvier, Michel

研究方向