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Repurposing Vandetanib plus Everolimus for the Treatment of ACVR1-Mutant Diffuse Intrinsic Pontine Glioma 万德他尼联合依维莫司治疗ACVR1-Mutant弥漫性内在性脑桥胶质瘤 Carvalho, Diana M.; Richardson, Peter J.; Olaciregui, Nagore; Stankunaite, Reda; Lavarino, Cinzia; Molinari, Valeria; Corley, Elizabeth A.; Smith, Daniel P.; Ruddle, Ruth; Donovan, Adam; Pal, Akos; Raynaud, Florence, I; Temelso, Sara; Mackay, Alan; Overington, John P.; Phelan, Anne; Sheppard, David; Mackinnon, Andrew; Zebian, Bassel; Al-Sarraj, Safa; Merve, Ashirwad; Pryce, Jeremy; Grill, Jacques; Hubank, Michael; Cruz, Ofelia; Morales La Madrid, Andres; Mueller, Sabine; Carcaboso, Angel M.; Carceller, Fernando; Jones, Chris 分享 收藏
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Artificial intelligence, drug repurposing and peer review 人工智能、药物再利用和同行评审 Levin, Jeremy M.; Oprea, Tudor I.; Davidovich, Sagie; Clozel, Thomas; Overington, John P.; Vanhaelen, Quentin; Cantor, Charles R.; Bischof, Evelyne; Zhavoronkov, Alex 分享 收藏
Improving the odds of drug development success through human genomics: modelling study 通过人类基因组学提高药物开发成功的几率: 建模研究 Hingorani, Aroon D.; Kuan, Valerie; Finan, Chris; Kruger, Felix A.; Gaulton, Anna; Chopade, Sandesh; Sofat, Reecha; MacAllister, Raymond J.; Overington, John P.; Hemingway, Harry; Denaxas, Spiros; Prieto, David; Casas, Juan Pablo 分享 收藏
Setting Our Sights on Infectious Diseases 将目光投向传染病 De Rycker, Manu; Horn, David; Aldridge, Bree; Amewu, Richard K.; Barry, Clifton E., III; Buckner, Frederick S.; Cook, Sarah; Ferguson, Michael A. J.; Gobeau, Nathalie; Herrmann, Jennifer; Herding, Paul; Hope, William; Keiser, Jennifer; Lafuente-Monasterio, Maria Jose; Leeson, Paul D.; Leroy, Didier; Manjunatha, Ujjini H.; McCarthy, James; Miles, Timothy J.; Mizrahi, Valerie; Moshynets, Olena; Niles, Jacquin; Overington, John P.; Pottage, John; Rao, Srinivasa P. S.; Read, Kevin D.; Ribeiro, Isabela; Silver, Lynn L.; Southern, Jen; Spangenberg, Thomas; Sundar, Shyam; Taylor, Caitlin; Van Voorhis, Wes; White, Nicholas J.; Wyllie, Susan; Wyatt, Paul G.; Gilbert, Ian H. 分享 收藏
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Unexplored therapeutic opportunities in the human genome (vol 17, pg 317, 2018) 人类基因组中未开发的治疗机会 (第17卷，317页，2018页) Oprea, Tudor I.; Bologa, Cristian G.; Brunak, Soren; Campbell, Allen; Gan, Gregory N.; Gaulton, Anna; Gomez, Shawn M.; Guha, Rajarshi; Hersey, Anne; Holmes, Jayme; Jadhav, Ajit; Jensen, Lars Juhl; Johnson, Gary L.; Karlson, Anneli; Leach, Andrew R.; Ma'ayan, Avi; Malovannaya, Anna; Mani, Subramani; Mathias, Steven L.; McManus, Michael T.; Meehan, Terrence F.; von Mering, Christian; Muthas, Daniel; Dac-Trung Nguyen; Overington, John P.; Papadatos, George; Qin, Jun; Reich, Christian; Roth, Bryan L.; Schurer, Stephan C.; Simeonov, Anton; Sklar, Larry A.; Southall, Noel; Tomita, Susumu; Tudose, Ilinca; Ursu, Oleg; Vidovic, Dusica; Waller, Anna; Westergaard, David; Yang, Jeremy J.; Zahoranszky-Kohalmi, Gergely 分享 收藏
Unexplored therapeutic opportunities in the human genome 人类基因组中未开发的治疗机会 Oprea, Tudor I.; Bologa, Cristian G.; Brunak, Soren; Campbell, Allen; Gan, Gregory N.; Gaulton, Anna; Gomez, Shawn M.; Guha, Rajarshi; Hersey, Anne; Holmes, Jayme; Jadhav, Ajit; Jensen, Lars Juhl; Johnson, Gary L.; Karlson, Anneli; Leach, Andrew R.; Ma'ayan, Avi; Malovannaya, Anna; Mani, Subramani; Mathias, Stephen L.; McManus, Michael T.; Meehan, Terrence F.; von Mering, Christian; Muthas, Daniel; Dac-Trung Nguyen; Overington, John P.; Papadatos, George; Qin, Jun; Reich, Christian; Roth, Bryan L.; Schurer, Stephan C.; Simeonov, Anton; Sklar, Larry A.; Southall, Noel; Tomita, Susumu; Tudose, Ilinca; Ursu, Oleg; Vidovic, Dusica; Waller, Anna; Westergaard, David; Yang, Jeremy J.; Zahoranszky-Kohalmi, Gergely 分享 收藏
Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions 药物目标共享: 为药物-目标相互作用建立共识知识库的社区努力 Tang, Jing; Tanoli, Zia-ur-Rehman; Ravikumar, Balaguru; Alam, Zaid; Rebane, Anni; Vaha-Koskela, Markus; Peddinti, Gopal; van Adrichem, Arjan J.; Wakkinen, Janica; Jaiswal, Alok; Karjalainen, Ella; Gautam, Prson; He, Liye; Parri, Elina; Khan, Suleiman; Gupta, Abhishekh; Ali, Mehreen; Yetukuri, Laxman; Gustavsson, Anna-Lena; Seashore-Ludlow, Brinton; Hersey, Anne; Leach, Andrew R.; Overington, John P.; Repasky, Gretchen; Wennerberg, Krister; Aittokallio, Tero 分享 收藏
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The druggable genome and support for target identification and validation in drug development 药物基因组及其对药物开发中靶标识别和验证的支持 Finan, Chris; Gaulton, Anna; Kruger, Felix A.; Lumbers, R. Thomas; Shah, Tina; Engmann, Jorgen; Galver, Luana; Kelley, Ryan; Karlsson, Anneli; Santos, Rita; Overington, John P.; Hingorani, Aroon D.; Casas, Juan P. 分享 收藏
A comprehensive map of molecular drug targets 分子药物靶点的综合图谱 Santos, Rita; Ursu, Oleg; Gaulton, Anna; Bento, A. Patricia; Donadi, Ramesh S.; Bologa, Cristian G.; Karlsson, Anneli; Al-Lazikani, Bissan; Hersey, Anne; Oprea, Tudor I.; Overington, John P. 分享 收藏
Pharos: Collating protein information to shed light on the druggable genome Pharos: 整理蛋白质信息以阐明可药用基因组 Dac-Trung Nguyen; Mathias, Stephen; Bologa, Cristian; Brunak, Soren; Fernandez, Nicolas; Gaulton, Anna; Hersey, Anne; Holmes, Jayme; Jensen, Lars Juhl; Karlsson, Anneli; Liu, Guixia; Ma'ayan, Avi; Mandava, Geetha; Mani, Subramani; Mehta, Saurabh; Overington, John; Patel, Juhee; Rouillard, Andrew D.; Schurer, Stephan; Sheils, Timothy; Simeonov, Anton; Sklar, Larry A.; Southall, Noel; Ursu, Oleg; Vidovic, Dusica; Waller, Anna; Yang, Jeremy; Jadhav, Ajit; Oprea, Tudor I.; Guha, Rajarshi 分享 收藏
The ChEMBL database in 2017 ChEMBL数据库2017年 Gaulton, Anna; Hersey, Anne; Nowotka, Michal; Bento, A. Patricia; Chambers, Jon; Mendez, David; Mutowo, Prudence; Atkinson, Francis; Bellis, Louisa J.; Cibrian-Uhalte, Elena; Davies, Mark; Dedman, Nathan; Karlsson, Anneli; Magarinos, Maria Paula; Overington, John P.; Papadatos, George; Smit, Ines; Leach, Andrew R. 分享 收藏
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Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles 开源药物发现: 源自Tres Cantos芳基吡咯的高效抗疟化合物 Williamson, Alice E.; Ylioja, Paul M.; Robertson, Murray N.; Antonova-Koch, Yevgeniya; Avery, Vicky; Baell, Jonathan B.; Batchu, Harikrishna; Batra, Sanjay; Burrows, Jeremy N.; Bhattacharyya, Soumya; Calderon, Felix; Charman, Susan A.; Clark, Julie; Crespo, Benigno; Dean, Matin; Debbert, Stefan L.; Delves, Michael; Dennis, Adelaide S. M.; Deroose, Frederik; Duffy, Sandra; Fletcher, Sabine; Giaever, Guri; Hallyburton, Irene; Gamo, Francisco-Javier; Gebbia, Marinella; Guy, R. Kiplin; Hungerford, Zoe; Kirk, Kiaran; Lafuente-Monasterio, Maria J.; Lee, Anna; Meister, Stephan; Nislow, Corey; Overington, John P.; Papadatos, George; Patiny, Luc; Pham, James; Ralph, Stuart A.; Ruecker, Andrea; Ryan, Eileen; Southan, Christopher; Srivastava, Kumkum; Swain, Chris; Tarnowski, Matthew J.; Thomson, Patrick; Turner, Peter; Wallace, Iain M.; Wells, Timothy N. C.; White, Karen; White, Laura; Willis, Paul; Winzeler, Elizabeth A.; Wittlin, Sergio; Todd, Matthew H. 分享 收藏
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