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J

Jonathan D. Powell

Johns Hopkins University
H指数:72
被引数:2.5万

个人简介

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工作经历

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Retraction Note: Re-engineered BCG overexpressing cyclic di-AMP augments trained immunity and exhibits improved efficacy against bladder cancer

撤稿说明：经过重新设计的BCG过量表达环二腺苷酸，增强了训练性免疫，并显示出对膀胱癌的改进效果。

Nature Communications
IF15.7
2026-03-230
OAAI
Alok Kumar Singh; Monali Praharaj; Kara A. Lombardo; Takahiro Yoshida; Andres Matoso; Alex S. Baras; Liang Zhao; Geetha Srikrishna; Joy Huang; Pankaj Prasad; Jonathan D. Powell; Max Kates; David McConkey; Drew M. Pardoll; William R. Bishai; Trinity J. Bivalacqua
Distinct myeloid-derived suppressor cell populations in human glioblastoma

人类胶质母细胞瘤中不同的髓源性抑制细胞群

Science
IF45.8
2025-01-010
OAAI
Christina Jackson; Christopher Cherry; Sadhana Bom; Arbor G. Dykema; Rulin Wang; Elizabeth A. Thompson; Ming Zhang; Runzhe Li; Zhicheng Ji; Wenpin Hou; Wentao Zhan; Hao Zhang; John Hyunkuk Choi; Ajay M. Vaghasia; Landon John Hansen; William Lee Wang; Brandon Hwa-Lin Bergsneider; Kate M. Jones; Fausto J. Rodríguez; JON D. WEINGART; Calixto‐Hope G. Lucas; Jonathan D. Powell; Jennifer H. Elisseeff; Srinivasan Yegnasubramanian; Michael K. Lim; Chetan Bettegowda; Hongkai Ji; Drew M. Pardoll
Glutamine antagonist prodrug JHU083 reprograms immunosuppressive tumor-associated macrophages to drive tumor immunity in urologic cancers
CANCER RESEARCH
IF16.6
2023-06-020
PRE
Praharaj, Monali; Shen, Fan; Lee, Alex J.; Zhao, Liang; Nirschl, Thomas R.; Wang, Xiaoxu; Theodros, Debebe; Singh, Alok K.; Williams, Raekwon A.; Sena, Laura A.; Thompson, Elizabeth A.; Tam, Ada; Yegnasubramanian, Srinivasan; Pearce, Edward J.; Leone, Robert D.; Alt, Jesse; Rais, Rana; Slusher, Barbara S.; Pardoll, Drew M.; Powell, Jonathan D.; Zarif, Jelani C.
First-in-human phase 1 studies of PTPN2/1 inhibitors ABBV-CLS-484 and ABBV-CLS-579 in locally advanced or metastatic tumors
CANCER RESEARCH
IF16.6
2023-04-143
PRE
LoRusso, Patricia M.; Aller, Emiliano Calvo; Yamamoto, Noboru; Lin, Chia-Chi; Beck, Thaddeus; Sommerhalder, David; Oh, Do-Youn; Powderly, John D.; Golan, Talia; Abraham, Linu Sara; Hayflick, Joel S.; Uziel, Tamar; Brunsdon, Priya; Munasinghe, Wijith; Paddock, Marcia; Hartman, Cathleen Brdlik; Powell, Jonathan; Medeiros, Bruno; Neagu, Martha R.; Carneiro, Benedito A.
Glutamine antagonist prodrug JHU083 reprograms immunosuppressive tumor-associated macrophages (TAMs) to drive tumor immunity in urologic cancers
CANCER RESEARCH
IF16.6
2023-04-041
PRE
Praharaj, Monali; Shen, Fan; Lee, Alex J.; Zhao, Liang; Nirschl, Thomas; Wang, Xiaoxu; Theodros, Debebe; Singh, Alok K.; Williams, Raekwon A.; Sena, Laura A.; Thompson, Elizabeth A.; Tam, Ada; Yegnasubramanian, Srinivasan; Pearce, Edward J.; Leone, Robert D.; Alt, Jesse; Rais, Rana; Slusher, Barbara S.; Pardoll, Andrew M.; Powell, Jonathan D.; Zarif, Jelani C.
Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug

肿瘤靶向代谢抑制剂前药DRP-104的发现

SCIENCE ADVANCES
IF12.5
2022-11-1652
OAAI
Rais, Rana; Lemberg, Kathryn M.; Tenora, Lukas; Arwood, Matthew L.; Pal, Arindom; Alt, Jesse; Wu, Ying; Lam, Jenny; Aguilar, Joanna Marie H.; Zhao, Liang; Peters, Diane E.; Tallon, Carolyn; Pandey, Rajeev; Thomas, Ajit G.; Dash, Ranjeet P.; Seiwert, Tanguy; Majer, Pavel; Leone, Robert D.; Powell, Jonathan D.; Slusher, Barbara S.
Functional characterization of CD4+ T cell receptors crossreactive for SARS-CoV-2 and endemic coronaviruses
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2021-05-1761
OA
Dykema, Arbor G.; Zhang, Boyang; Woldemeskel, Bezawit A.; Garliss, Caroline C.; Cheung, Laurene S.; Choudhury, Dilshad; Zhang, Jiajia; Aparicio, Luis; Bom, Sadhana; Rashid, Rufiaat; Caushi, Justina X.; Hsiue, Emily Han-Chung; Cascino, Katherine; Thompson, Elizabeth A.; Kwaa, Abena K.; Singh, Dipika; Thapa, Sampriti; Ordonez, Alvaro A.; Pekosz, Andrew; D'Alessio, Franco R.; Powell, Jonathan D.; Yegnasubramanian, Srinivasan; Zhou, Shibin; Pardoll, Drew M.; Ji, Hongkai; Cox, Andrea L.; Blankson, Joel N.; Smith, Kellie N.
Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance

抗原驱动的EGR2表达是耗尽CD8 T细胞稳定性和维持所必需的

NATURE COMMUNICATIONS
IF15.7
2021-05-1327
OAAI
Wagle, Mayura, V; Vervoort, Stephin J.; Kelly, Madison J.; Van der Byl, Willem; Peters, Timothy J.; Martin, Ben P.; Martelotto, Luciano G.; Nuessing, Simone; Ramsbottom, Kelly M.; Torpy, James R.; Knight, Deborah; Reading, Sinead; Thia, Kevin; Miosge, Lisa A.; Howard, Debbie R.; Gloury, Renee; Gabriel, Sarah S.; Utzschneider, Daniel T.; Oliaro, Jane; Powell, Jonathan D.; Luciani, Fabio; Trapani, Joseph A.; Johnstone, Ricky W.; Kallies, Axel; Goodnow, Christopher C.; Parish, Ian A.

研究方向

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M
Maureen R. Horton
H 指数:46论文数:127被引数:9,635
C
Chirag H. Patel
H 指数:20论文数:90被引数:4,585
M
Min Hee Oh
H 指数:26论文数:82被引数:5,000
B
Barbara S. Slusher
H 指数:67论文数:588被引数:2.0万
I
Im‐Hong Sun
H 指数:17论文数:44被引数:3,365
R
Rana Rais
H 指数:38论文数:310被引数:5,931
R
Robert D. Leone
H 指数:17论文数:100被引数:3,388
L
Liang Zhao
H 指数:35论文数:164被引数:5,909
S
Samuel L. Collins
H 指数:16论文数:48被引数:1,478
G
Greg M. Delgoffe
H 指数:52论文数:340被引数:1.7万