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P

Paul S. Mischel

Stanford University
H指数:109
被引数:4.0万

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AmpliconSuite: an end-to-end workflow for analyzing focal amplifications in cancer genomes

AmpliconSuite：用于分析癌症基因组中焦点扩增的端到端工作流程

Nature Methods
IF32.1
2026-10-160
OAAI
Jens Luebeck; Ted Liefeld; Ivy Tsz-Lo Wong; Edwin Huang; Forrest Kim; Bhargavi Dameracharla; Michael Chan; Rohil Ahuja; Kyra Fetter; Dhruv Khatri; Kaiyuan Zhu; Thorin Tabor; Daniel Schreyer; Gino Prasad; Aditi Gnanasekar; Siavash Raeisi Dehkordi; Simone Spandau; Michał Adamaszek; Rishaan Kenkre; Tushar Agashe; Devika Torvi; Mădălina Giurgiu-Kraljič; Soyeon Kim; Hoon Kim; Peter Bailey; Roel G. W. Verhaak; Viraj Deshpande; Michael Reich; Paul S. Mischel; Jill P. Mesirov; Vineet Bafna
Micronuclear ecDNA constrains tumor cell fitness and is associated with favorable patient survival

微核中的染色体外DNA限制肿瘤细胞适应性并与患者良好生存相关

Nature Genetics
IF29
2026-10-120
OAAI
Lotte Brückner; Robin Xu; Jun Tang; Aditi Gnanasekar; Alexander Herrmann; Ivy Tsz-Lo Wong; Shu Zhang; Fengyu Tu; Madison Pilon; Alexander Kukalev; Katharina Pardon; Olga Sidorova; Joshua Atta; Qinghao Yu; Giulia Montuori; Davide Pradella; Mila Ilić; Kentaro Suina; Marco Novais-Cruz; Sarah Kaltenbach; Denise Treue; Mădălina Giurgiu-Kraljič; Sergej Herzog; Ann-Sophie Hollinger; Nadine Wittstruck; Martina Fernandez; Nicole Wolozyn; Finnja Becker; Varvara-Rigina Louma; Xiaowei Yan; Rachel Schmargon; Jan R. Dörr; David Gamlin; Annika Lehmann; Dennis Gürgen; Matthias Richter; Frank Dubois; Fabrizio Simeoni; Betheney R. Pennycook; Alastair Hamilton; Ralph K. Lindemann; Courtney Dawes; Gabriel Balmus; Barbara Hero; Matthias Fischer; Vineet Bafna; Roel Verhaak; Geoffrey Wahl; Yang Liu; Richard P. Koche; Stamatis Papathanasiou; René Medema; Bastiaan Spanjaard; Andrea Ventura; Ana Pombo; Weini Huang; Monika Scheer; Benjamin Werner; Howard Y. Chang; Paul S. Mischel; Anton G. Henssen
scAmp enables focal gene amplification analysis from single-cell data

scAmp实现从单细胞数据中分析局部基因扩增

Nature Communications
IF15.7
2026-08-080
OA
Matthew G. Jones; Natasha E. Weiser; King L. Hung; Xiaowei Yan; Sangya Agarwal; Jens Luebeck; Aditi Gnanasekar; Shu Zhang; Ivy Tsz-Lo Wong; Jun Tang; Brooke E. Howitt; Ellis J. Curtis; Kevin Yu; John C. Rose; Katerina Kraft; Valeh Valiollah Pour Amiri; Leena Satpathy; Vineet Bafna; Paul S. Mischel; Howard Y. Chang
ERO1a fosters glioblastoma aggressiveness and metabolic flexibility by regulating mitochondria-associated membrane dynamics

ERO1a通过调控线粒体相关膜动力学促进胶质母细胞瘤的侵袭性和代谢适应性

Nature Cell Biology
IF19.1
2026-06-120
OAAI
Arthur Bassot; Lola Violy; Lucas Gorka; Lavinia Cigalotto; Balasubramaniam Namasivayam; Ivan Mikaelian; Emma St Johnston; Chao Han; Rudy Gadet; Beatrice Alpha-Bazin; Laurine Moindrot; Emilie Clement; Helena Dragic; Marine Crépin; Olivier Berdeaux; Christophe Vanbelle; Mélina Gautier; Alice Cariou; Louis Larrouquere; Chunmei Wei; Thomas Gudermann; Jann N. Sarkaria; Ester Zito; Pierre-Yves Dietrich; Paul R. Walker; Ivan Nemazanyy; Hubert Lincet; Jean Armengaud; Jennifer Rieusset; Paul S. Mischel; Elmina Mammadova-Bach; Thomas Simmen; Denis Martinvalet; Marie Castets; Erika Cosset
High-depth whole genome sequencing of premalignant breast lesions reveals rearrangement hotspots and personalized management opportunities

高危癌前乳腺癌病变的高深度全基因组测序揭示重排热点及个性化管理机会

Nature Communications
IF15.7
2026-05-190
OAAI
Lucia Chmelova; Helen R. Davies; Andrea Degasperi; Giuseppe Rinaldi; Leon Wils; Daniella Black; Yasin Memari; Gene C. C. Koh; Scott Shooter; Lennart Mulder; Petra Kristel; Karoly Szuhai; Gino Prasad; Ivy Tsz-Lo Wong; Jens Luebeck; Yogesh Kumar; Jan Czarnecki; Shadi Basyuni; Zoya Kingsbury; Mark T. Ross; Øystein Garred; Margit Riis; Karin T. Lande; Johan Vallon-Christersson; Anna Ehinger; Amit Agrawal; Stuart A. McIntosh; Vineet Bafna; Paul S. Mischel; Jelle Wesseling; Johan Staaf; Therese Sørlie; Esther H. Lips; Serena Nik-Zainal
Genetic elements promote retention of extrachromosomal DNA in cancer cells

遗传元件促进癌细胞中外源染色体的DNA保留

Nature
IF48.5
2025-11-190
OAAI
Venkat Sankar; King L. Hung; Aditi Gnanasekar; Ivy Tsz-Lo Wong; Quanming Shi; Katerina Kraft; Matthew G. Jones; Britney Jiayu He; Xiaowei Yan; Julia A. Belk; Kevin J. Liu; Sangya Agarwal; Sean K. Wang; Anton G. Henssen; Paul S. Mischel; Howard Y. Chang
Enhancer activation from transposable elements in extrachromosomal DNA

细胞外DNA中转座元件的增强子激活

Nature Cell Biology
IF19.1
2025-10-210
OAAI
Katerina Kraft; Sedona E. Murphy; Matthew G. Jones; Quanming Shi; Aarohi Bhargava-Shah; Christy Luong; King L. Hung; Britney J. He; Rui Li; Seung Kuk Park; Michael T. Montgomery; Natasha E. Weiser; Yanbo Wang; Jens Luebeck; Vineet Bafna; Jef D. Boeke; Paul S. Mischel; Alistair N. Boettiger; Howard Y. Chang
Engineered extrachromosomal oncogene amplifications promote tumorigenesis
Nature
IF48.5
2024-12-180
OAAI
Davide Pradella; Minsi Zhang; Rui Gao; Melissa A. Yao; Katarzyna M. Gluchowska; Ylenia Cendon-Florez; Tanmay Mishra; Gaspare La Rocca; Moritz Weigl; Ziqi Jiao; Hieu H. M. Nguyen; Marta Lisi; Mateusz M. Ozimek; Chiara Mastroleo; Kevin Chen; Felix Grimm; Jens Luebeck; Shu Zhang; Andrea Alice Zolli; Eric G. Sun; Bhargavi Dameracharla; Zhengqiao Zhao; Yuri Pritykin; Carlie Sigel; Howard Y. Chang; Paul S. Mischel; Vineet Bafna; Cristina R. Antonescu; Andrea Ventura
Coordinated inheritance of extrachromosomal DNAs in cancer cells

癌细胞中染色体外dna的协调遗传

Nature
IF48.5
2024-11-060
OAAI
King L. Hung; Matthew G. Jones; Ivy Tsz-Lo Wong; Ellis J. Curtis; Joshua T. Lange; Britney Jiayu He; Jens Luebeck; Rachel Schmargon; Elisa Scanu; Lotte Brückner; Xiaowei Yan; Rui Li; Aditi Gnanasekar; Rocío Chamorro González; Julia A. Belk; Zhonglin Liu; Bruno Melillo; Vineet Bafna; Jan R. Dörr; Benjamin Werner; Weini Huang; Benjamin F. Cravatt; Anton G. Henssen; Paul S. Mischel; Howard Y. Chang
Enhancing transcription–replication conflict targets ecDNA-positive cancers
Nature
IF48.5
2024-11-060
OAAI
Jun Tang; Natasha E. Weiser; Guiping Wang; Sudhir Chowdhry; Ellis J. Curtis; Yanding Zhao; Ivy Tsz-Lo Wong; Georgi K. Marinov; Rui Li; Philip Hanoian; Edison Tse; Salvador Garcia Mojica; Ryan Hansen; Joshua Plum; Auzon Steffy; Snezana Milutinovic; S. Todd Meyer; Jens Luebeck; Yanbo Wang; Shu Zhang; Nicolas Altemose; Christina Curtis; William J. Greenleaf; Vineet Bafna; Stephen J. Benkovic; Anthony B. Pinkerton; Shailaja Kasibhatla; Christian A. Hassig; Paul S. Mischel; Howard Y. Chang
Origins and impact of extrachromosomal DNA
Nature
IF48.5
2024-11-060
OAAI
Chris Bailey; Oriol Pich; Kerstin Thol; Thomas B. K. Watkins; Jens Luebeck; Andrew Rowan; Georgia Stavrou; Natasha E. Weiser; Bhargavi Dameracharla; Robert Bentham; Wei-Ting Lu; Jeanette Kittel; S. Y. Cindy Yang; Brooke E. Howitt; Natasha Sharma; Maria Litovchenko; Roberto Salgado; King L. Hung; Alex J. Cornish; David A. Moore; Richard S. Houlston; Vineet Bafna; Howard Y. Chang; Serena Nik-Zainal; Nnennaya Kanu; Nicholas McGranahan; Adrienne M. Flanagan; Paul S. Mischel; Mariam Jamal-Hanjani; Charles Swanton

研究方向

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Timothy F. Cloughesy
H 指数:128论文数:1,355被引数:6.2万
W
Webster K. Cavenee
H 指数:119论文数:585被引数:8.7万
L
Linda M. Liau
H 指数:83论文数:676被引数:3.4万
V
Vineet Bafna
H 指数:80论文数:452被引数:5.9万
H
Howard Y. Chang
H 指数:162论文数:744被引数:13.5万
J
Jens Luebeck
H 指数:24论文数:149被引数:4,201
W
William H. Yong
H 指数:67论文数:562被引数:1.7万
K
Kenta Masui
H 指数:30论文数:141被引数:4,770
I
Ingo K. Mellinghoff
H 指数:79论文数:616被引数:3.7万
S
Sihan Wu
H 指数:28论文数:160被引数:4,704