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An antibiotic that mediates immune destruction of senescent cancer cells 一种介导衰老癌细胞免疫破坏的抗生素 Raffi, Gabriele Casagrande; Chen, Jian; Feng, Xuezhao; Chen, Zhen; Lieftink, Cor; Deng, Shuang; Mo, Jinzhe; Zeng, Chuting; Steur, Marit; Wang, Jing; Bleijerveld, Onno B.; Hoekman, Liesbeth; van der Wel, Nicole; Wang, Feng; Beijersbergen, Roderick; Zheng, Jian; Bernards, Rene; Wang, Liqin 分享 收藏
Cancer drug-tolerant persister cells: from biological questions to clinical opportunities 癌症药物耐受性持久细胞: 从生物学问题到临床机会 Russo, Mariangela; Chen, Mengnuo; Mariella, Elisa; Peng, Haoning; Rehman, Sumaiyah K.; Sancho, Elena; Sogari, Alberto; Toh, Tzen S.; Balaban, Nathalie Q.; Batlle, Eduard; Bernards, Rene; Garnett, Mathew J.; Hangauer, Matthew; Leucci, Eleonora; Marine, Jean-Christophe; O'Brien, Catherine A.; Oren, Yaara; Patton, E. Elizabeth; Robert, Caroline; Rosenberg, Susan M.; Shen, Shensi; Bardelli, Alberto 分享 收藏
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Dual Inhibition of CDK4/6 and XPO1 Induces Senescence With Acquired Vulnerability to CRBN-Based PROTAC Drugs Wang, Hui; Yuan, Shengxian; Zheng, Quan; Zhang, Sisi; Zhang, Qianqian; Ji, Shuyi; Wang, Wei; Cao, Ying; Guo, Yuchen; Yang, Xupeng; Geng, Haigang; Yang, Fan; Xi, Shuijun; Jin, Guangzhi; Zhang, Jianming; Gao, Qiang; Bernards, Rene; Qin, Wenxin; Wang, Cun 分享 收藏
The phosphatase inhibitor LB-100 creates neoantigens in colon cancer cells through perturbation of mRNA splicing Dias, Matheus H.; Liudkovska, Vladyslava; Navarro, Jasmine Montenegro; Giebel, Lisanne; Champagne, Julien; Papagianni, Chrysa; Bleijerveld, Onno B.; Velds, Arno; Agami, Reuven; Bernards, Rene; Ciesla, Maciej 分享 收藏
Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy Dias, Matheus Henrique; Friskes, Anoek; Wang, Siying; Neto, Joao M. Fernandes; van Gemert, Frank; Mourragui, Soufiane; Papagianni, Chrysa; Kuiken, Hendrik J.; Mainardi, Sara; Alvarez-Villanueva, Daniel; Lieftink, Cor; Morris, Ben; Dekker, Anna; van Dijk, Emma; Wilms, Lieke H. S.; da Silva, Marcelo S.; Jansen, Robin A.; Mulero-Sanchez, Antonio; Malzer, Elke; Vidal, August; Santos, Cristina; Salazar, Ramon; Wailemann, Rosangela A. M.; Torres, Thompson E. P.; De Conti, Giulia; Raaijmakers, Jonne A.; Snaebjornsson, Petur; Yuan, Shengxian; Qin, Wenxin; Kovach, John S.; Armelin, Hugo A.; te Riele, Hein; van Oudenaarden, Alexander; Jin, Haojie; Beijersbergen, Roderick L.; Villanueva, Alberto; Medema, Rene H.; Bernards, Rene 分享 收藏
Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse Chen, Mengnuo; Mainardi, Sara; Lieftink, Cor; Velds, Arno; de Rink, Iris; Yang, Chen; Kuiken, Hendrik J.; Morris, Ben; Edwards, Finn; Jochems, Fleur; van Tellingen, Olaf; Boeije, Manon; Proost, Natalie; Jansen, Robin A.; Qin, Shifan; Jin, Haojie; van der Mijn, J. C. Koen; Schepers, Arnout; Venkatesan, Subramanian; Qin, Wenxin; Beijersbergen, Roderick L.; Wang, Liqin; Bernards, Rene 分享 收藏
Small- molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in KRAS- mutant cancers Jansen, Robin A.; Mainardi, Sara; Dias, Matheus Henrique; Bosma, Astrid; van Dijk, Emma; Selig, Roland; Albrecht, Wolfgang; Laufer, Stefan A.; Zender, Lars; Bernards, Rene 分享 收藏
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TARGETED INHIBITION OF THREE MAJOR PROLIFERATION PATHWAYS IN GLIOBLASTOMA INDUCES SENESCENCE THROUGH A MITOCHONDRIA-DEPENDENT MECHANISM Baltira, C.; Mayayo-Peralta, I.; Guillen-Navarro, M.; Thijssen, B.; Alkan, F.; Pello, K.; Fedorushkova, D. M.; Their, A.; Silva, J.; Jochems, F.; Bleijerveld, O.; Janssen, H.; Faller, W. J.; Bernards, R.; de Gooijer, M. C.; van Tellingen, O. 分享 收藏
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