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R

Roderick L. Beijersbergen

Netherlands Cancer Institute
H指数:59
被引数:2.3万

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A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator

全基因组CRISPR筛选在人前列腺癌细胞中揭示了巨噬细胞介导的细胞杀伤的驱动因子，并将AR定位为肿瘤内源性免疫调节因子

Oncogene
IF7.3
2026-07-280
PRE
Anniek Zaalberg; Audrey Lacoste; Emma Minnee; Isabel Mayayo-Peralta; Karianne Schuurman; Sebastian Gregoricchio; Thijs A. van Schaik; Liesbeth Hoekman; Dapei Li; Eva Corey; Hans Janssen; Cor Lieftink; Stefan Prekovic; Natalie Proost; Marieke van de Ven; Serge Zander; Maarten Altelaar; Peter S. Nelson; Roderick L. Beijersbergen; Wilbert Zwart; Andries M. Bergman
DOT1L Shapes ncPRC1-Target Gene Repression to Maintain Germinal Center B-Cell Identity of Diffuse Large B-cell Lymphoma

DOT1L调控ncPRC1靶基因抑制以维持弥漫性大B细胞淋巴瘤的生发中心B细胞特性

Blood
IF23.1
2026-06-020
PRE
Camiel Göbel; Rachele Niccolai; Sebastian Gregoricchio; Marnix H. P. de Groot; Stijn Kneefel; Maaike Kreft; Hendrik J. Kuiken; Cor Lieftink; Nils Eickhoff; Liesbeth Hoekman; Onno Bleijerveld; Wilbert Zwart; Roderick L. Beijersbergen; Fred van Leeuwen; Heinz Jacobs
Cholesterol biosynthesis as a drug-induced vulnerability in diffuse large B cell lymphoma insensitive to EZH2 inhibition

胆固醇生物合成作为对EZH2抑制不敏感的弥漫性大B细胞淋巴瘤的药物诱导易感靶点

Neoplasia
IF7.7
2025-10-270
OAAI
Rachele Niccolai; Camiel Göbel; Klevis Ndoj; Maaike Kreft; Hendrik J. Kuiken; Cor Lieftink; Ben Morris; Sietse D. Yska; Sebastian Hendrix; Bram van den Broek; Vincent Pappalardo; Marie José Kersten; Roderick L. Beijersbergen; Noam Zelcer; Fred van Leeuwen; Heinz Jacobs
Epigenetic profiling identifies markers of endocrine resistance and therapeutic options for metastatic castration-resistant prostate cancer

表观遗传谱分析鉴定了内分泌抵抗的标志物及转移性去势抵抗性前列腺癌的治疗选择

Cell Reports Medicine
IF10.6
2025-07-020
OAAI
Tesa M. Severson; Emma Minnee; Yanyun Zhu; Karianne Schuurman; Holly M. Nguyen; Lisha G. Brown; Sini Hakkola; Renee Menezes; Sebastian Gregoricchio; Yongsoo Kim; Jeroen Kneppers; Simon Linder; Suzan Stelloo; Cor Lieftink; Michiel S. van der Heijden; Matti Nykter; Vincent van der Noort; Joyce Sanders; Ben Morris; Guido Jenster; Geert JLH van Leenders; Mark Pomerantz; Matthew L. Freedman; Roderick L. Beijersbergen; Alfonso Urbanucci; Lodewyk Wessels; Peter S. Nelson; Eva Corey; Stefan Prekovic; Wilbert Zwart; Andries M. Bergman
An antibiotic that mediates immune destruction of senescent cancer cells

一种介导衰老癌细胞免疫破坏的抗生素

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-12-180
OAAI
Raffi, Gabriele Casagrande; Chen, Jian; Feng, Xuezhao; Chen, Zhen; Lieftink, Cor; Deng, Shuang; Mo, Jinzhe; Zeng, Chuting; Steur, Marit; Wang, Jing; Bleijerveld, Onno B.; Hoekman, Liesbeth; van der Wel, Nicole; Wang, Feng; Beijersbergen, Roderick; Zheng, Jian; Bernards, Rene; Wang, Liqin
Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy
CANCER DISCOVERY
IF33.3
2024-03-266
OAAI
Dias, Matheus Henrique; Friskes, Anoek; Wang, Siying; Neto, Joao M. Fernandes; van Gemert, Frank; Mourragui, Soufiane; Papagianni, Chrysa; Kuiken, Hendrik J.; Mainardi, Sara; Alvarez-Villanueva, Daniel; Lieftink, Cor; Morris, Ben; Dekker, Anna; van Dijk, Emma; Wilms, Lieke H. S.; da Silva, Marcelo S.; Jansen, Robin A.; Mulero-Sanchez, Antonio; Malzer, Elke; Vidal, August; Santos, Cristina; Salazar, Ramon; Wailemann, Rosangela A. M.; Torres, Thompson E. P.; De Conti, Giulia; Raaijmakers, Jonne A.; Snaebjornsson, Petur; Yuan, Shengxian; Qin, Wenxin; Kovach, John S.; Armelin, Hugo A.; te Riele, Hein; van Oudenaarden, Alexander; Jin, Haojie; Beijersbergen, Roderick L.; Villanueva, Alberto; Medema, Rene H.; Bernards, Rene
Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse
CELL REPORTS MEDICINE
IF10.6
2024-03-018
OAAI
Chen, Mengnuo; Mainardi, Sara; Lieftink, Cor; Velds, Arno; de Rink, Iris; Yang, Chen; Kuiken, Hendrik J.; Morris, Ben; Edwards, Finn; Jochems, Fleur; van Tellingen, Olaf; Boeije, Manon; Proost, Natalie; Jansen, Robin A.; Qin, Shifan; Jin, Haojie; van der Mijn, J. C. Koen; Schepers, Arnout; Venkatesan, Subramanian; Qin, Wenxin; Beijersbergen, Roderick L.; Wang, Liqin; Bernards, Rene
Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity

管腔型乳腺癌的身份取决于糖皮质激素受体活性的丧失

EMBO MOLECULAR MEDICINE
IF8.3
2023-10-305
OAAI
Prekovic, Stefan; Chalkiadakis, Theofilos; Roest, Merel; Roden, Daniel; Lutz, Catrin; Schuurman, Karianne; Opdam, Mark; Hoekman, Liesbeth; Abbott, Nina; Tesselaar, Tanja; Wajahat, Maliha; Dwyer, Amy R.; Mayayo-Peralta, Isabel; Gomez, Gabriela; Altelaar, Maarten; Beijersbergen, Roderick; Gyorffy, Balazs; Young, Leonie; Linn, Sabine; Jonkers, Jos; Tilley, Wayne; Hickey, Theresa; Vareslija, Damir; Swarbrick, Alexander; Zwart, Wilbert
Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1-versus BRCA2-deficient mammary tumors
CELL REPORTS
IF6.9
2023-05-0116
OAAI
Bhin, Jinhyuk; Dias, Mariana Paes; Gogola, Ewa; Rolfs, Frank; Piersma, Sander R.; de Bruijn, Roebi; de Ruiter, Julian R.; van den Broek, Bram; Duarte, Alexandra A.; Sol, Wendy; van der Heijden, Ingrid; Andronikou, Christina; Kaiponen, Taina S.; Bakker, Lara; Lieftink, Cor; Morris, Ben; Beijersbergen, Roderick L.; van de Ven, Marieke; Jimenez, Connie R.; Wessels, Lodewyk F. A.; Rottenberg, Sven; Jonkers, Jos
PAXIP1 and STAG2 converge to maintain 3D genome architecture and facilitate promoter/enhancer contacts to enable stress hormone-dependent transcription
NUCLEIC ACIDS RESEARCH
IF13.1
2023-04-189
OAAI
Mayayo-Peralta, Isabel; Gregoricchio, Sebastian; Schuurman, Karianne; Yavuz, Selcuk; Zaalberg, Anniek; Kojic, Aleksandar; Abbott, Nina; Geverts, Bart; Beerthuijzen, Suzanne; Siefert, Joseph; Severson, Tesa M.; van Baalen, Martijn; Hoekman, Liesbeth; Lieftink, Cor; Altelaar, Maarten; Beijersbergen, Roderick L.; Houtsmuller, Adriaan B.; Prekovic, Stefan; Zwart, Wilbert

研究方向

暂未获取到该数据
C
Cor Lieftink
H 指数:33论文数:250被引数:6,037
R
René Bernards
H 指数:111论文数:884被引数:7.7万
B
Ben Morris
H 指数:22论文数:142被引数:2,101
H
Hendrik J. Kuiken
H 指数:12论文数:69被引数:955
L
Liqin Wang
H 指数:33论文数:176被引数:6,398
W
Wilbert Zwart
H 指数:53论文数:647被引数:1.1万
L
Lodewyk F.A. Wessels
H 指数:89论文数:1,030被引数:4.7万
B
Bastiaan Evers
H 指数:27论文数:115被引数:4,470
W
Wouter Nijkamp
H 指数:10论文数:54被引数:2,587
金
金浩杰
H 指数:37论文数:150被引数:6,772