Day, James E. H.; Berdini, Valerio; Castro, Joan; Chessari, Gianni; Davies, Thomas G.; Day, Philip J.; Denis, Jeffrey D. St; Fujiwara, Hideto; Fukaya, Satoshi; Hamlett, Christopher C. F.; Hearn, Keisha; Hiscock, Steven D.; Holvey, Rhian S.; Ito, Satoru; Kandola, Navrohit; Kodama, Yasuo; Liebeschuetz, John W.; Martins, Vanessa; Matsuo, Kenichi; Mortenson, Paul N.; Muench, Sandra; Nakatsuru, Yoko; Ochiiwa, Hiroaki; Palmer, Nicholas; Peakman, Torren; Price, Amanda; Reader, Michael; Rees, David C.; Rich, Sharna J.; Shah, Alpesh; Shibata, Yoshihiro; Smyth, Tomoko; Twigg, David G.; Wallis, Nicola G.; Williams, Glyn; Wilsher, Nicola E.; Woodhead, Andrew; Shimamura, Tadashi; Johnson, Christopher N.

What's wrong with drug development for sickle cell disease?

镰状细胞病药物研发的问题是什么？

HEMASPHERE

IF14.6

2025-02-061

OAAI

Infections in sickle cell disease

HAEMATOLOGICA

IF7.9

2024-11-210

OAAI

Long-term follow-up of givosiran treatment in patients with acute intermittent porphyria from a phase 1/2, 48-month open-label extension study

ORPHANET JOURNAL OF RARE DISEASES

IF3.5

2024-10-031

OAAI

Discovery of ASTX295, a potent, next-generation small molecule antagonist of MDM2 with differentiated pharmacokinetic profile

CANCER RESEARCH

IF16.6

2024-03-221

PRE

Ahn, Maria; Bevan, Luke; Buck, Ildiko; Cano, Celine; Castro, Juan; Cons, Ben; Endicott, Jane; Fazal, Lynsey; Ferrari, Nicola; Hardcastle, Ian; Hearn, Keisha; Holvey, Rhian; Howard, Steven; Johnson, Chris; Jennings, Claire; Kucia-Tran, Justyna; Kyle, Suzanne; Lunec, John; Lyons, John; Miller, Duncan; Rees, David; Noble, Martin; Newell, David R.; Reeks, Judith; Saini, Harpreet; Denis, Jeffrey St.; Tamanini, Emiliano; Thomas, Huw; Thompson, Neil; Vinkovic, Mladen; Ward, George; Wallis, Nicola; Walton, Hugh; Wedge, Stephen; Williams, Pamela; Willmore, Elaine; Wilshire, Nicola; Zhao, Yan; Chessari, Gianni

Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-03-113

PRE

Day, James E. H.; Berdini, Valerio; Castro, Joan; Chessari, Gianni; Davies, Thomas G.; Day, Philip J.; St. Denis, Jeffrey D.; Fujiwara, Hideto; Fukaya, Satoshi; Hamlett, Christopher C. F.; Hearn, Keisha; Hiscock, Steven D.; Holvey, Rhian S.; Ito, Satoru; Kandola, Navrohit; Kodama, Yasuo; Liebeschuetz, John W.; Martins, Vanessa; Matsuo, Kenichi; Mortenson, Paul N.; Muench, Sandra; Nakatsuru, Yoko; Ochiiwa, Hiroaki; Palmer, Nicholas; Peakman, Torren; Price, Amanda; Reader, Michael; Rees, David C.; Rich, Sharna J.; Shah, Alpesh; Shibata, Yoshihiro; Smyth, Tomoko; Twigg, David G.; Wallis, Nicola G.; Williams, Glyn; Wilsher, Nicola E.; Woodhead, Andrew; Shimamura, Tadashi; Johnson, Christopher N.

Global burden of sickle cell disease in 2021

LANCET HAEMATOLOGY

IF17.7

2023-10-010

PRE

Invasive Bacterial Infections in Children With Sickle Cell Disease: 2014-2019

PEDIATRICS

IF6.4

2023-09-283

PRE

Males with sickle cell disease have higher risks of cerebrovascular disease, increased inflammation, and a reduced response to hydroxyurea

AMERICAN JOURNAL OF HEMATOLOGY

IF9.9

2023-08-300

OAAI

Defining global strategies to improve outcomes in sickle cell disease: a Lancet Haematology Commission

LANCET HAEMATOLOGY

IF17.7

2023-08-0141

OAAI

Piel, Frederic B.; Rees, David C.; DeBaun, Michael R.; Nnodu, Obiageli; Ranque, Brigitte; Thompson, Alexis A.; Ware, Russell E.; Abboud, Miguel R.; Abraham, Allistair; Ambrose, Emmanuela E.; Andemariam, Biree; Colah, Roshan; Colombatti, Raffaella; Conran, Nicola; Costa, Fernando F.; Cronin, Robert M.; de Montalembert, Mariane; Elion, Jacques; Esrick, Erica; Greenway, Anthea L.; Idris, Ibrahim M.; Issom, David-Zacharie; Jain, Dipty; Jordan, Lori C.; Kaplan, Zane S.; King, Allison A.; Lloyd-Puryear, Michele; Oppong, Samuel A.; Sharma, Akshay; Sung, Lillian; Tshilolo, Leon; Wilkie, Diana J.; Ohene-Frempong, Kwaku

Structural connectivity mediates the relationship between blood oxygenation and cognitive function in sickle cell anemia

结构连接介导镰状细胞性贫血患者血液氧合与认知功能的关系

BLOOD ADVANCES

IF7.1

2023-05-243

OAAI

Determinants of severity in sickle cell disease

镰状细胞病严重程度的决定因素

BLOOD REVIEWS

IF5.7

2022-11-0128

OAAI