Masad J. Damha - Publications, H-index & Citations

Masad J. Damha

mcgill university

52H指数

285论文数

8.6K被引数

收录论文 116

发表时间

CRISPR RNA architecture steers Cas9 catalysis and fidelity via a guide repeat clasp motif CRISPR RNA 架构通过引导重复夹持基序引导 Cas9 催化作用和保真度

Nucleic Acids Research

IF13.1

2026-08-14

OAAI

Ramadevi Chilamkurthy; Sruthi Sudhakar; Adrian A Pater; Michael S Bosmeny; Francis Stabile; Adam Katolik; S Harikrishna; Fatima El Azzouzi; Rolf Turk; Masad J Damha; Sabrina Leslie; Sergey Korolev; P I Pradeepkumar; Keith T Gagnon; null

Lewis Acidic Bentonite Clays as Catalysts for 5′ Deprotection of Nucleosides and Dinucleotides 酸性蒙脱土粘土作为核苷和二核苷5′位脱保护催化剂

Organic Letters

IF5

2026-05-20

PREAI

Julian Marlyn; Abhishek Arora; Masad J. Damha

Direct targeting of C9ORF72 repeat RNA with fluorinated antisense oligonucleotides 氟化反义寡核苷酸直接靶向C9ORF72重复RNA

Nucleic Acids Research

IF13.1

2026-04-25

OAAI

Halle M Barber; Mansi A Parasrampuria; Jerónimo Jurado-Arjona; Andrea Gamir-Morralla; Benedikt Berninger; Carlos González; Keith T Gagnon; Masad J Damha; Miguel Garavís; null

A nanopore-based HIV-1 reference epitranscriptome 基于纳米孔的HIV-1参考表观转录组

Nucleic Acids Research

IF13.1

2026-04-13

PREAI

Bosmeny, Michael S.; Pater, Adrian A.; Zhang, Li; Larkai, Lydia L.; Sha, Beverly E.; Lyu, Zidi; Damha, Masad J.; Mamede, Joao, I; Gagnon, Keith T.

Synthesis of long and functionally active RNAs facilitated by acetal levulinic ester chemistry 利用乙缩醛糠酸酯化学促进长功能活性RNA的合成

Nucleic Acids Research

IF13.1

2026-01-27

PREAI

Lyu, Zidi; Katolik, Adam; Yaseen, Iqra; Pater, Adrain A.; Robert, Francis; Huang, Sidong; Gagnon, Keith T.; Unrau, Peter J.; Damha, Masad J.

A modified X10-23 DNAzyme that can better access large, structured RNA targets 一种经过修饰的X10-23 DNAzyme，能够更好地接近大型、结构化的RNA靶标

Nucleic Acids Research

IF13.1

2026-01-13

PREAI

Nurmi, Connor; Barber, Halle M.; Kaur, Harneesh; Brennan, John D.; Damha, Masad J.; Li, Yingfu

Fluorogenic oligonucleotide cleavage probes with a branched linker improve RNA detection 具有分支连接子的荧光寡核苷酸切割探针提高了RNA检测

NUCLEIC ACIDS RESEARCH

IF13.1

2025-03-07

OAAI

Maru, Bruktawit; Edinboro, Ayodele; Katolik, Adam; El-Khoury, Roberto; Basran, Kaleena; Wahba, Alexander S.; Damha, Masad J.; Luedtke, Nathan W.; Mckeague, Maureen

Chemical engineering of CRISPR-Cas systems for therapeutic application 用于治疗应用的crispr-cas系统的化学工程

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2024-12-17

PREAI

Barber, Halle M.; Pater, Adrian A.; Gagnon, Keith T.; Damha, Masad J.; O'Reilly, Daniel

Formation of left-handed helices by C2′-fluorinated nucleic acids under physiological salt conditions

NUCLEIC ACIDS RESEARCH

IF13.1

2024-06-14

OAAI

El-Khoury, Roberto; Cabrero, Cristina; Movilla, Santiago; Kaur, Harneesh; Friedland, David; Dominguez, Arnau; Thorpe, James D.; Roman, Morgane; Orozco, Modesto; Gonzalez, Carlos; Damha, Masad J.

Synthesis of Seven-Membered Ring Nucleosides and Serendipitous Simmons-Smith O-Glycosylation

ORGANIC LETTERS

IF5

2024-06-12

PREAI

Jana, Sunit Kumar; Damha, Masad J.

The debranching enzyme Dbr1 regulates lariat turnover and intron splicing

NATURE COMMUNICATIONS

IF15.7

2024-05-30

OAAI

Buerer, Luke; Clark, Nathaniel E.; Welch, Anastasia; Duan, Chaorui; Taggart, Allison J.; Townley, Brittany A.; Wang, Jing; Soemedi, Rachel; Rong, Stephen; Lin, Chien-Ling; Zeng, Yi; Katolik, Adam; Staley, Jonathan P.; Damha, Masad J.; Mosammaparast, Nima; Fairbrother, William G.

In-cell NMR suggests that DNA i-motif levels are strongly depleted in living human cells

NATURE COMMUNICATIONS

IF15.7

2024-03-05

OAAI

Viskova, Pavlina; Istvankova, Eva; Rynes, Jan; Dzatko, Simon; Loja, Tomas; Zivkovic, Martina Lenarcic; Rigo, Riccardo; El-Khoury, Roberto; Serrano-Chacon, Israel; Damha, Masad J.; Gonzalez, Carlos; Mergny, Jean-Louis; Foldynova-Trantirkova, Silvie; Trantirek, Lukas

Characterization of tRNA splicing enzymes RNA ligase and tRNA 2′-phosphotransferase from the pathogenic fungi Mucorales

RNA

IF5

2024-01-18

PREAI

Ghosh, Shreya; Dantuluri, Swathi; Jacewicz, Agata; Sanchez, Ana M.; Abdullahu, Leonora; Damha, Masad J.; Schwer, Beate; Shuman, Stewart

Challenges of Assessing Exon 53 Skipping of the Human DMD Transcript with Locked Nucleic Acid-Modified Antisense Oligonucleotides in a Mouse Model for Duchenne Muscular Dystrophy

NUCLEIC ACID THERAPEUTICS

IF4.7

2023-12-01

OAAI

Engelbeen, Sarah; O'Reilly, Daniel; van de Vijver, Davy; Verhaart, Ingrid; van Putten, Maaike; Hariharan, Vignesh; Hassler, Matthew; Khvorova, Anastasia; Damha, Masad J.; Aartsma-Rus, Annemieke

Telomeric i-motifs and C-strands inhibit parallel G-quadruplex extension by telomerase

NUCLEIC ACIDS RESEARCH

IF13.1

2023-09-23

OAAI

El-Khoury, Roberto; Roman, Morgane; Assi, Hala Abou; Moye, Aaron L.; Bryan, Tracy M.; Damha, Masad J.

Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-09-01

OAAI

Clark, Nathaniel E.; Katolik, Adam; Gallant, Pascal; Welch, Anastasia; Murphy, Eileen; Buerer, Luke; Schorl, Christoph; Naik, Nandita; Naik, Mandar T.; Holloway, Stephen P.; Cano, Kristin; Weintraub, Susan T.; Howard, Katherine M.; Hart, P. John; Jogl, Gerwald; Damha, Masad J.; Fairbrother, William G.

Sequence-Controlled Spherical Nucleic Acids: Gene Silencing, Encapsulation, and Cellular Uptake

NUCLEIC ACID THERAPEUTICS

IF4.7

2023-08-01

PREAI

Kaviani, Sepideh; Fakih, Hassan H. H.; Asohan, Jathavan; Katolik, Adam; Damha, Masad J. J.; Sleiman, Hanadi F. F.

Binding to the conserved and stably folded guide RNA pseudoknot induces Cas12a conformational changes during ribonucleoprotein assembly

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-05-01

OAAI

Sudhakar, Sruthi; Barkau, Christopher L.; Chilamkurthy, Ramadevi; Barber, Halle M.; Pater, Adrian A.; Moran, Sean D.; Damha, Masad J.; Pradeepkumar, P. I.; Gagnon, Keith T.

i-Motif folding intermediates with zero-nucleotide loops are trapped by 2′-fluoroarabinocytidine via F•••H and O•••H hydrogen bonds

COMMUNICATIONS CHEMISTRY

IF6.2

2023-02-16

OAAI

El-Khoury, Roberto; Macaluso, Veronica; Hennecker, Christopher; Mittermaier, Anthony K.; Orozco, Modesto; Gonzalez, Carlos; Garavis, Miguel; Damha, Masad J.

Small Molecule-Templated DNA Hydrogel with Record Stiffness Integrates and Releases DNA Nanostructures and Gene Silencing Nucleic Acids

ADVANCED SCIENCE

IF14.1

2023-02-08

OAAI

Lachance-Brais, Christophe; Rammal, Mostafa; Asohan, Jathavan; Katolik, Adam; Luo, Xin; Saliba, Daniel; Jonderian, Antranik; Damha, Masad J.; Harrington, Matthew J.; Sleiman, Hanadi F.

研究方向