Robert J. Weatheritt - Publications, H-index & Citations

Robert J. Weatheritt

european molecular biology laboratory (embl)

34H指数

71论文数

9.6K被引数

收录论文 38

发表时间

Isoform-specific m6A deposition and coordinated splicing shape mammalian transcriptome evolution 异构体特异性的m6A沉积和协调性剪接塑造哺乳动物转录组进化

Nature Communications

IF15.7

2026-04-21

OAAI

Gabriela Santos-Rodriguez; Akanksha Srivastava; Agin Ravindran; Favour O. Oyelami; Chi Kin Ip; Pallavi Gupta; Jeanette Villanueva; Helen E. King; Abigail Grootveld; Alexandra Sneddon; James Blackburn; Ishaan Gupta; Helaine Graziele Santos Vieira; Nikolay E. Shirokikh; Eduardo Eyras; Robert J. Weatheritt

Systematic profiling of cytosolic membraneless organelles reveals enrichment of oncogenic mRNA upon oxidative stress 系统性地对细胞质无膜细胞器进行表征揭示了氧化应激下癌基因mRNA的富集

Cell Reports

IF6.9

2026-04-04

OAAI

Savannah O’Connell; Helen E. King; Peter Kjer-Hansen; Karina Pazaky; Gabriela Santos Rodriguez; Daisy Kavanagh; Helaine Graziele S. Vieira; Javier Fernandez-Chamorro; Robert J. Weatheritt

Isoform-specific single-cell perturb-seq reveals distinct functions of alternative promoters in drug response

Nucleic Acids Research

IF13.1

2026-02-27

PREAI

King, Helen E.; O'Connell, Savannah; Kavanagh, Daisy; Mason, Sofia; McCool, Cerys; Fernandez-Chamorro, Javier; Chaffer, Christine L.; Clark, Susan J.; Vieira, Helaine Graziele S.; Sterne-Weiler, Timothy; Weatheritt, Robert J.

Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma 联合抑制FACT和BET破坏转录以抑制弥漫性中线胶质瘤小鼠模型的肿瘤生长

Science Translational Medicine

IF14.6

2026-01-14

PREAI

Holliday, Holly; Khan, Aaminah; Ehteda, Anahid; Nguyen, Hieu; Ross, Samuel E.; Jayatilleke, Nisitha; Gopalakrishnan, Anjana; Wang, Eyden; Sanguino, Yolanda Colino; Kavanagh, Daisy; Guo, Xinyi; Liu, Jie; Lawrence, David; Sun, Claire X.; Lehmann, Rebecca; Ip, Chi Kin; Lee, Alvin; Rangel-Sanchez, Laura; Li, Wenyan; Salomon, Robert; Firestein, Ron; Weatheritt, Robert J.; Valdes-Mora, Fatima; Dinger, Marcel E.; Phoenix, Timothy N.; Mayoh, Chelsea; Rayner, Benjamin S.; Tsoli, Maria; Ziegler, David S.

CHROMATIN REMODELING WITH COMBINED FACT AND BET INHIBITION DISRUPTS ONCOGENIC TRANSCRIPTION IN DIFFUSE MIDLINE GLIOMA 联合FACT和BET抑制的染色质重塑破坏弥漫性中线胶质瘤中的致癌转录

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Holliday, Holly; Khan, Aaminah; Ehteda, Anahid; Nguyen, Hieu; Ross, Samuel; Jayatilleke, Nisitha; Gopalakrishnan, Anjana; Wang, Eyden; Guo, Xinyi; Sanguino, Yolanda Colino; Kavanagh, Daisy; Liu, Jie; Lawrence, David; Sun, Claire; Lehmann, Rebecca; Ip, Chi Kin; Lee, Alvin; Li, Wenyan; Salomon, Robert; Firestein, Ron; Weatheritt, Robert; Valdes-Mora, Fatima; Dinger, Marcel; Phoenix, Timothy; Mayoh, Chelsea; Rayner, Benjamin; Tsoli, Maria; Ziegler, David

Protein isoform-centric therapeutics: expanding targets and increasing specificity

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2024-09-04

PREAI

Kjer-Hansen, Peter; Phan, Tri Giang; Weatheritt, Robert J.

Genome-scale exon perturbation screens uncover exons critical for cell fitness

MOLECULAR CELL

IF16.6

2024-07-01

OAAI

Xiao, Mei-Sheng; Damodaran, Arun Prasath; Kumari, Bandana; Dickson, Ethan; Xing, Kun; On, Tyler A.; Parab, Nikhil; King, Helen E.; Perez, Alexendar R.; Guiblet, Wilfried M.; Duncan, Gerard; Che, Anney; Chari, Raj; Andresson, Thorkell; Vidigal, Joana A.; Weatheritt, Robert J.; Aregger, Michael; Gonatopoulos-Pournatzis, Thomas

Systematic analysis of alternative exon-dependent interactome remodeling reveals multitasking functions of gene regulatory factors

MOLECULAR CELL

IF16.6

2023-12-01

OAAI

Roth, Jonathan F.; Braunschweig, Ulrich; Wu, Mingkun; Li, Jack Daiyang; Lin, Zhen-Yuan; Larsen, Brett; Weatheritt, Robert J.; Gingras, Anne-Claude; Blencowe, Benjamin J.

The function of alternative splicing in the proteome: rewiring protein interactomes to put old functions into new contexts 蛋白质组中选择性剪接的功能: 重新连接蛋白质相互作用组以将旧功能置于新的环境中

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2023-11-30

PREAI

Kjer-Hansen, Peter; Weatheritt, Robert J.

Fetal exposure to valproic acid dysregulates the expression of autism-linked genes in the developing cerebellum

TRANSLATIONAL PSYCHIATRY

IF6.2

2023-04-05

OAAI

Guerra, Marika; Medici, Vanessa; Weatheritt, Robert; Corvino, Valentina; Palacios, Daniela; Geloso, Maria Concetta; Farini, Donatella; Sette, Claudio

Global detection of human variants and isoforms by deep proteome sequencing 通过深度蛋白质组测序对人类变体和同工型进行全局检测

NATURE BIOTECHNOLOGY

IF41.7

2023-03-23

OAAI

Sinitcyn, Pavel; Richards, Alicia L.; Weatheritt, Robert J.; Brademan, Dain R.; Marx, Harald; Shishkova, Evgenia; Meyer, Jesse G.; Hebert, Alexander S.; Westphall, Michael S.; Blencowe, Benjamin J.; Cox, Juergen; Coon, Joshua J.

Active DNA demethylation of developmental cis-regulatory regions predates vertebrate origins

SCIENCE ADVANCES

IF12.5

2022-12-02

OAAI

Skvortsova, Ksenia; Bertrand, Stephanie; Voronov, Danila; Duckett, Paul E.; Ross, Samuel E.; Magri, Marta Silvia; Maeso, Ignacio; Weatheritt, Robert J.; Skarmeta, Jose Luis Gomez; Arnone, Maria Ina; Escriva, Hector; Bogdanovic, Ozren

Alu-minating the Mechanisms Underlying Primate Cortex Evolution

BIOLOGICAL PSYCHIATRY

IF9

2022-11-01

PREAI

Wang, Juli; Weatheritt, Robert; Voineagu, Irina

Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis

MOLECULAR CELL

IF16.6

2022-08-01

OAAI

Han, Hong; Best, Andrew J.; Braunschweig, Ulrich; Mikolajewicz, Nicholas; Li, Jack Daiyang; Roth, Jonathan; Chowdhury, Fuad; Mantica, Federica; Nabeel-Shah, Syed; Parada, Guillermo; Brown, Kevin R.; O'Hanlon, Dave; Wei, Jiarun; Yao, Yuxi; Abou Zid, Abdelrahman; Comsa, Lim Caden; Jen, Mark; Wang, Jenny; Datti, Alessandro; Gonatopoulos-Pournatzis, Thomas; Weatheritt, Robert J.; Greenblatt, Jack F.; Wrana, Jeffrey L.; Irimia, Manuel; Gingras, Anne-Claude; Moffat, Jason; Blencowe, Benjamin J.

Systematic mapping of nuclear domain-associated transcripts reveals speckles and lamina as hubs of functionally distinct retained introns

MOLECULAR CELL

IF16.6

2022-03-01

OAAI

Barutcu, A. Rasim; Wu, Mingkun; Braunschweig, Ulrich; Dyakov, Boris J. A.; Luo, Zheng; Turner, Kyle M.; Durbic, Tanja; Zhen-Yuan Lin; Weatheritt, Robert J.; Maass, Philipp G.; Gingras, Anne-Claude; Blencowe, Benjamin J.

Evolutionary dynamics of circular RNAs in primates 环状rna在灵长类动物中的进化动力学

ELIFE

IF0

2021-09-20

PREAI

Santos-Rodriguez, Gabriela; Voineagu, Irina; Weatheritt, Robert J.

Differential contribution of transcriptomic regulatory layers in the definition of neuronal identity

NATURE COMMUNICATIONS

IF15.7

2021-01-12

OAAI

Ha, Kevin C. H.; Sterne-Weiler, Timothy; Morris, Quaid; Weatheritt, Robert J.; Blencowe, Benjamin J.

A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum

CELL REPORTS

IF6.9

2020-06-01

OAAI

Farini, Donatella; Cesari, Eleonora; Weatheritt, Robert J.; La Sala, Gina; Naro, Chiara; Pagliarini, Vittoria; Bonvissuto, Davide; Medici, Vanessa; Guerra, Marika; Di Pietro, Chiara; Rizzo, Francesca Romana; Musella, Alessandra; Carola, Valeria; Centonze, Diego; Blencowe, Benjamin J.; Marazziti, Daniela; Sette, Claudio

Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions

MOLECULAR CELL

IF16.6

2020-03-01

OAAI

Gonatopoulos-Pournatzis, Thomas; Niibori, Rieko; Salter, Eric W.; Weatheritt, Robert J.; Tsang, Brian; Farhangmehr, Shaghayegh; Liang, Xinyi; Braunschweig, Ulrich; Roth, Jonathan; Zhang, Shen; Henderson, Tyler; Sharma, Eesha; Quesnel-Vallieres, Mathieu; Permanyer, Jon; Maier, Stefan; Georgiou, John; Irimia, Manuel; Sonenberg, Nahum; Forman-Kay, Julie D.; Gingras, Anne-Claude; Collingridge, Graham L.; Woodin, Melanie A.; Cordes, Sabine P.; Blencowe, Benjamin J.

Shifts in Ribosome Engagement Impact Key Gene Sets in Neurodevelopment and Ubiquitination in Rett Syndrome

CELL REPORTS

IF6.9

2020-03-01

OAAI

Rodrigues, Deivid C.; Mufteev, Marat; Weatheritt, Robert J.; Djuric, Ugljesa; Ha, Kevin C. H.; Ross, P. Joel; Wei, Wei; Piekna, Alina; Sartori, Maria A.; Byres, Loryn; Mok, Rebecca S. F.; Zaslavsky, Kirill; Pasceri, Peter; Diamandis, Phedias; Morris, Quaid; Blencowe, Benjamin J.; Ellis, James

研究方向