Srinivas Niranj Chandrasekaran

imaging platform

18H指数

49论文数

1.5K被引数

收录论文 13

发表时间

nELISA: a high-throughput, high-plex platform enables quantitative profiling of the inflammatory secretome nELISA：一种高通量、高复合平台，能够实现炎症分泌组的高定量分析

Nature Methods

IF32.1

2025-11-07

OAAI

Milad Dagher; Grant Ongo; Nathaniel Robichaud; Jinglin Kong; Woojong Rho; Ivan Teahulos; Arya Tavakoli; Samantha Bovaird; Shahem Merjaneh; Andrew Tan; Kiran Edwardson; Christelle Scheepers; Andy Ng; Andy Hajjar; Baly Sow; Michael Vrouvides; Andy Lee; Philippe DeCorwin-Martin; Shafqat Rasool; Jiamin Huang; Timothy Erps; Spencer Coffin; Narges M. Rashidi; Yu Han; Srinivas Niranj Chandrasekaran; Lisa Miller; Maria Kost-Alimova; Adam Skepner; Shantanu Singh; Anne E. Carpenter; Jeffrey D. Munzar; David Juncker

Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations 用匹配的化学和遗传扰动处理的细胞的300万张图像和形态特征

NATURE METHODS

IF32.1

2024-04-09

OAAI

Chandrasekaran, Srinivas Niranj; Cimini, Beth A.; Goodale, Amy; Miller, Lisa; Kost-Alimova, Maria; Jamali, Nasim; Doench, John G.; Fritchman, Briana; Skepner, Adam; Melanson, Michelle; Kalinin, Alexandr A.; Arevalo, John; Haghighi, Marzieh; Caicedo, Juan C.; Kuhn, Daniel; Hernandez, Desiree; Berstler, James; Shafqat-Abbasi, Hamdah; Root, David E.; Swalley, Susanne E.; Garg, Sakshi; Singh, Shantanu; Carpenter, Anne E.

Optimizing the Cell Painting assay for image-based profiling 优化基于图像的分析的细胞绘画分析

NATURE PROTOCOLS

IF16

2023-06-21

OAAI

Cimini, Beth A.; Chandrasekaran, Srinivas Niranj; Kost-Alimova, Maria; Miller, Lisa; Goodale, Amy; Fritchman, Briana; Byrne, Patrick; Garg, Sakshi; Jamali, Nasim; Logan, David J.; Concannon, John B.; Lardeau, Charles-Hugues; Mouchet, Elizabeth; Singh, Shantanu; Abbasi, Hamdah Shafqat; Aspesi, Jr Peter; Boyd, Justin D.; Gilbert, Tamara; Gnutt, David; Hariharan, Santosh; Hernandez, Desiree; Hormel, Gisela; Juhani, Karolina; Melanson, Michelle; Mervin, Lewis H.; Monteverde, Tiziana; Pilling, James E.; Skepner, Adam; Swalley, Susanne E.; Vrcic, Anita; Weisbart, Erin; Williams, Guy; Yu, Shan; Zapiec, Bolek; Carpenter, Anne E.

Enantioseparation of 3-Hydroxycarboxylic Acids via Diastereomeric Salt Formation by 2-Amino-1,2-diphenylethanol (ADPE) and Cinchonidine

MOLECULES

IF4.6

2022-12-23

OAAI

Chandrasekaran, Srinivas; Tambo, Masaki; Yamazaki, Yuta; Muramatsu, Tatsuro; Kanda, Yusuke; Hirose, Takuji; Kodama, Koichi

Morphology and gene expression profiling provide complementary information for mapping cell state 形态学和基因表达谱为绘制细胞状态提供了补充信息

CELL SYSTEMS

IF7.7

2022-11-01

OAAI

Way, Gregory P.; Natoli, Ted; Adeboye, Adeniyi; Litichevskiy, Lev; Yang, Andrew; Lu, Xiaodong; Caicedo, Juan C.; Cimini, Beth A.; Karhohs, Kyle; Logan, David J.; Rohban, Mohammad H.; Kost-Alimova, Maria; Hartland, Kate; Bornholdt, Michael; Chandrasekaran, Srinivas Niranj; Haghighi, Marzieh; Weisbart, Erin; Singh, Shantanu; Subramanian, Aravind; Carpenter, Anne E.

Image-based profiling for drug discovery: due for a machine-learning upgrade?基于图像的药物发现分析: 是否需要机器学习升级？

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2020-12-22

193

OAAI

Chandrasekaran, Srinivas Niranj; Ceulemans, Hugo; Boyd, Justin D.; Carpenter, Anne E.

Functional Class I and II amino acid-activating enzymes can be coded by opposite strands of the same gene (Vol 290, pg 19710, 2015)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-11-01

OAAI

Martinez-Rodriguez, Luis; Erdogan, Ozguen; Jimenez-Rodriguez, Mariel; Gonzalez-Rivera, Katiria; Williams, Tishan; Li, Li; Weinreb, Violotta; Collier, Martha; Chandrasekaran, Srinivas Niranj; Ambroggio, Xavier; Kuhlman, Brian; Carter, Charles W., Jr.

Functional Class I and II Amino Acid-activating Enzymes Can Be Coded by Opposite Strands of the Same Gene

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-08-01

OAAI

Martinez-Rodriguez, Luis; Erdogan, Ozguen; Jimenez-Rodriguez, Mariel; Gonzalez-Rivera, Katiria; Williams, Tishan; Li, Li; Weinreb, Violetta; Collier, Martha; Chandrasekaran, Srinivas Niranj; Ambroggio, Xavier; Kuhlman, Brian; Carter, Charles W., Jr.

Enhanced Amino Acid Selection in Fully Evolved Tryptophanyl-tRNA Synthetase, Relative to Its Urzyme, Requires Domain Motion Sensed by the D1 Switch, a Remote Dynamic Packing Motif

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-02-01

OAAI

Weinreb, Violetta; Li, Li; Chandrasekaran, Srinivas Niranj; Koehl, Patrice; Delarue, Marc; Carter, Charles W., Jr.

Statistical Evaluation of the Rodin-Ohno Hypothesis: Sense/Antisense Coding of Ancestral Class I and II Aminoacyl-tRNA Synthetases

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2013-05-14

OAAI

Chandrasekaran, Srinivas Niranj; Yardimci, Galip Guerkan; Erdogan, Ozguen; Roach, Jeffrey; Carter, Charles W., Jr.

Rational design of a ligand-controlled protein conformational switch

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-04-08

122

OAAI

Dagliyan, Onur; Shirvanyants, David; Karginov, Andrei V.; Ding, Feng; Fee, Lanette; Chandrasekaran, Srinivas N.; Freisinger, Christina M.; Smolen, Gromoslaw A.; Huttenlocher, Anna; Hahn, Klaus M.; Dokholyan, Nikolay V.

Rational Design of a Ligand-Controlled Protein Conformational Switch

BIOPHYSICAL JOURNAL

IF3.1

2013-01-01

OAAI

Dagliyan, Onur; Shirvanyants, David; Karginov, Andrei; Ding, Feng; Chandrasekaran, Srinivas N.; Freisinger, Christina M.; Smolen, Gromoslaw; Huttenlocher, Anna; Hahn, Klaus M.; Dokholyan, Nikolay V.

Molecular dynamics simulations of human and dog gastric lipases: Insights into domain movements

FEBS LETTERS

IF3

2010-10-20

PREAI

Selvan, Anitha; Seniya, Chandrabhan; Chandrasekaran, Srinivas Niranj; Siddharth, Nithyanand; Anishetty, Sharmila; Pennathur, Gautam

研究方向