Bin Zhang
H指数:93
被引数:4.9万
个人简介
A Professor of the Department of Genetics and Genomic Sciences and is Director of the Mount Sinai Center for Transformative Disease Modeling. With extensive experience in electrical engineering, computer science, and computational biology, the scholar builds highly predictive models for complex data, including handwritten document images and large-scale cancer genomic data. Over the past decade, the scholar has developed a series of influential gene network inference algorithms used for identification of novel pathways and gene targets, as well as development of drugs for diseases such as cancer, atherosclerosis, Alzheimer's, obesity, and diabetes. Recent work uncovered dramatic changes in gene-gene interaction patterns in Alzheimer's disease and pinpointed an immune/microglia gene network as the top pathway causally linked to the disease, published in Cell. The scholar was a recipient of the Best Paper Award of ICDAR 2003, the Seventh International Conference on Document Analysis and Recognition.
教育背景
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工作经历
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荣誉奖项
- Best Paper Award of ICDAR 2003 ─ the Seventh International Conference on Document Analysis and Recognition(2003)
丘脑容积改变介导阿尔茨海默病中类淋巴功能与认知功能障碍
蛋白质精氨酸甲基转移酶作为代谢调控因子:超越癌症的多种作用
神经外科ICU患者肠道微生物组纵向动态变化:肠球菌扩增作为微生物重塑的特征
BMC Microbiology
IF4.2
利用机器学习和网络生物学方法从血液转录组预测大脑基因表达
GigaScience
IF3.9
性别和APOE基因型特异的脑区对阿尔茨海默病的易损性
GeroScience
IF5.4
Glia
IF5.1
DAP12基因缺失降低雌性tau病小鼠的神经元SLIT2和脱髓鞘,并增强其大脑的恢复力。
靶向METTL1/m7G轴作为髓系白血病的治疗策略
Blood
IF23.1
基于机器学习的颈椎病前路颈椎间盘切除融合术后患者预后模型的开发与验证:一项多中心研究
JOR SPINE
IF3.9
通过衰老和神经退行性变的变革性神经病理学加速脑健康生物医学发现
Neuron
IF15
Gegen Qinlian Decoction 改善阿尔茨海默病通过 TLR4/ NF-κB/NLRP3 通路
TISSUE & CELL
IF2.5
零价铁(ZVI)与球磨协同改性生物炭去除地下水中铬(Cr(VI))的性能优化及机制研究
白质高信号的结构和微血管特征及其与小血管病变标志物的关联
SCIENTIFIC REPORTS
IF3.9
源自基于牛奶的婴儿和幼儿食品的序列型4 Cronobacter sakazakii的致病特性与机制
BMC MICROBIOLOGY
IF4.2
iDOMO:通过多重集合运算识别治疗疾病的药物组合
无监督的多尺度单细胞转录组聚类以识别细胞亚型的层次结构
GIGASCIENCE
IF3.9

