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Vegetable oils composition affects the intestinal lymphatic transport and systemic bioavailability of co-administered lipophilic drug cannabidiol Feng, Wanshan; Qin, Chaolong; Abdelrazig, Salah; Bai, Ziyu; Raji, Mekha; Darwish, Randa; Chu, YenJu; Ji, Liuhang; Gray, David A.; Stocks, Michael J.; Constantinescu, Cris S.; Barrett, David A.; Fischer, Peter M.; Gershkovich, Pavel 分享 收藏
Inclusion of Medium-Chain Triglyceride in Lipid-Based Formulation of Cannabidiol Facilitates Micellar Solubilization In Vitro, but In Vivo Performance Remains Superior with Pure Sesame Oil Vehicle Feng, Wanshan; Qin, Chaolong; Cipolla, Elena; Lee, Jong Bong; Zgair, Atheer; Chu, Yenju; Ortori, Catherine A.; Stocks, Michael J.; Constantinescu, Cris S.; Barrett, David A.; Fischer, Peter M.; Gershkovich, Pavel 分享 收藏
Design, Synthesis and In-Vitro Biological Evaluation of Antofine and Tylophorine Prodrugs as Hypoxia-Targeted Anticancer Agents Omran, Ziad; Guise, Chris P.; Chen, Linwei; Rauch, Cyril; Abdalla, Ashraf N.; Abdullah, Omeima; Sindi, Ikhlas A.; Fischer, Peter M.; Smaill, Jeff B.; Patterson, Adam V.; Liu, Yuxiu; Wang, Qingmin 分享 收藏
Oral administration of tipranavir with long-chain triglyceride results in moderate intestinal lymph targeting but no efficient delivery to HIV-1 reservoir in mesenteric lymph nodes Chu, Yenju; Qin, Chaolong; Feng, Wanshan; Sheriston, Charles; Khor, Yu Jane; Medrano-Padial, Concepcion; Watson, Birgit E.; Chan, Teddy; Ling, Binhua; Stocks, Michael J.; Fischer, Peter M.; Gershkovich, Pavel 分享 收藏
Structure-based design of highly selective 2,4,5-trisubstituted pyrimidine CDK9 inhibitors as anti-cancer agents Shao, Hao; Foley, David W.; Huang, Shiliang; Abbas, Abdullahi Y.; Lam, Frankie; Gershkovich, Pavel; Bradshaw, Tracey D.; Pepper, Chris; Fischer, Peter M.; Wang, Shudong 分享 收藏
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Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesity in Vivo Mouse Model Fromont, Christophe; Atzori, Alessio; Kaur, Divneet; Hashmi, Lubna; Greco, Graziella; Cabanillas, Alejandro; Nguyen, Huy Van; Jones, D. Heulyn; Garzon, Miguel; Varela, Ana; Stevenson, Brett; Iacobini, Greg P.; Lenoir, Marc; Rajesh, Sundaresan; Box, Clare; Kumar, Jitendra; Grant, Paige; Novitskaya, Vera; Morgan, Juliet; Sorrell, Fiona J.; Redondo, Clara; Kramer, Andreas; Harris, C. John; Leighton, Brendan; Vickers, Steven P.; Cheetham, Sharon C.; Kenyon, Colin; Grabowska, Anna M.; Overduin, Michael; Berditchevski, Fedor; Weston, Chris J.; Knapp, Stefan; Fischer, Peter M.; Butterworth, Sam 分享 收藏
Identification of a novel toxicophore in anti-cancer chemotherapeutics that targets mitochondrial respiratory complex I Stephenson, Zoe A.; Harvey, Robert F.; Pryde, Kenneth R.; Mistry, Sarah; Hardy, Rachel E.; Serreli, Riccardo; Chung, Injae; Allen, Timothy E. H.; Stoneley, Mark; MacFarlane, Marion; Fischer, Peter M.; Hirst, Judy; Kellam, Barrie; Willis, Anne E. 分享 收藏
A novel nucleoside rescue metabolic pathway may be responsible for therapeutic effect of orally administered cordycepin Lee, Jong Bong; Radhi, Masar; Cipolla, Elena; Gandhi, Raj D.; Sarmad, Sarir; Zgair, Atheer; Kim, Tae Hwan; Feng, Wanshan; Qin, Chaolong; Adrower, Cecilia; Ortori, Catherine A.; Barrett, David A.; Kagan, Leonid; Fischer, Peter M.; de Moor, Cornelia H.; Gershkovich, Pavel 分享 收藏
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Molecular profiling and combinatorial activity of CCT068127: a potent CDK2 and CDK9 inhibitor Whittaker, Steven R.; Barlow, Clare; Martin, Mathew P.; Mancusi, Caterina; Wagner, Steve; Self, Annette; Barrie, Elaine; Te Poele, Robert; Sharp, Swee; Brown, Nathan; Wilson, Stuart; Jackson, Wayne; Fischer, Peter M.; Clarke, Paul A.; Walton, Michael I.; McDonald, Edward; Blagg, Julian; Noble, Martin; Garrett, Michelle D.; Workman, Paul 分享 收藏
Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation Zgair, Atheer; Lee, Jong Bong; Wong, Jonathan C. M.; Tahal, Dhiaa A.; Aram, Jehan; Di Virgiliol, Daisy; McArthur, Joshua W.; Cheng, Yu-Kit; Hennig, Ivo M.; Barrett, David A.; Fischer, Peter M.; Constantinescu, Cris S.; Gershkovich, Pavel 分享 收藏
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Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease Baker, Jillian G.; Gardiner, Sheila M.; Woolard, Jeanette; Fromont, Christophe; Jadhav, Gopal P.; Mistry, Shailesh N.; Thompson, Kevin S. J.; Kellam, Barrie; Hill, Stephen J.; Fischer, Peter M. 分享 收藏
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