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A

Alex Avdeef

st. john's university

61H指数
200论文数
1.3W被引数
收录论文 72
发表时间
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Imipramine solubility-pH profiles: self-aggregation vs. commonion effect阿米替林溶解度-pH曲线：自聚集与同离子效应
errADMET and DMPK
IF4.3
err2025-12-01
err0
errOAAI
errMarkovic, Olivera S.; Pesic, Milos P.; Avdeef, Alex; Serajuddin, Abu T. M.; Verbic, Tatjana Z.
err分享
err收藏
Highly increasing solubility of clofazimine, an extremely water-insoluble basic drug, in lipid-based SEDDS using digestion products of long-chain lipids通过长链脂质消化产物，显著提高脂质基自乳化药物递送系统（SEDDS）中，一种极难溶于水的碱性药物氯法齐明的溶解度。
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2025-06-01
err0
PREAI
errKandagatla, Hari P.; Kathawala, Mufaddal H.; Syed, Amber; Verbic, Tatjana Z.; Avdeef, Alex
err分享
err收藏
Often neglected steps in transforming drug solubility from single measurement in pure water to physiologically-appropriate solubility-pH
errADMET AND DMPK
IF4.3
err2025-02-26
err0
errOAAI
errAvdeef, Alex
err分享
err收藏
Effects of Different Weak Small Organic Acids on Clofazimine Solubility in Aqueous Media
errPHARMACEUTICS
IF5.5
err2024-12-02
err0
errOAAI
errTopalovic, Igor A.; Markovic, Olivera S.; Pesic, Milos P.; Kathawala, Mufaddal H.; Kuentz, Martin; Avdeef, Alex; Serajuddin, Abu T. M.; Verbic, Tatjana Z.
err分享
err收藏
Supersolubilization and Amorphization of a Weakly Acidic Drug, Flurbiprofen, by applying Acid-Base supersolubilization (ABS) principle通过应用酸碱超增溶 (ABS) 原理对弱酸性药物氟比洛芬进行超增溶和非晶化
errINTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
err2024-09-01
err2
PREAI
errSyed, Mohammed I.; Kandagatla, Hari P.; Avdeef, Alex; Serajuddin, Abu T. M.
err分享
err收藏
A comparison of USP 2 and μDISS Profiler™ apparatus for studying dissolution phenomena of ibuprofen and its salts
errEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF4.7
err2024-02-01
err2
errOAAI
errZoeller, Laurin; Avdeef, Alex; Karlsson, Eva; Borde, Anders; Carlert, Sara; Saal, Christoph; Dressman, Jennifer
err分享
err收藏
Mechanistically transparent models for predicting aqueous solu-bility of rigid, slightly flexible, and very flexible drugs (MW<2000) Accuracy near that of random forest regression
errADMET AND DMPK
IF4.3
err2023-08-21
err2
errOAAI
errAvdeef, Alex
err分享
err收藏
Anomalous salting-out, self-association and pKa effects in the practically-insoluble bromothymol blue
errADMET AND DMPK
IF4.3
err2023-05-23
err3
errOAAI
errAvdeef, Alex
err分享
err收藏
Understanding the pH Dependence of Supersaturation State-A Case Study of Telmisartan
errPHARMACEUTICS
IF5.5
err2022-08-05
err4
errOAAI
errKadar, Szabina; Csicsak, Dora; Tozser, Petra; Farkas, Attila; Palla, Tamas; Mirzahosseini, Arash; Toth, Blanka; Toth, Gergo; Fiser, Bela; Horvath, Peter; Madarasz, Janos; Avdeef, Alex; Takacs-Novak, Krisztina; Sinko, Balint; Borbas, Eniko; Volgyi, Gergely
err分享
err收藏
Integration of In Silico, In Vitro and In Situ Tools for the Preformulation and Characterization of a Novel Cardio-Neuroprotective Compound during the Early Stages of Drug Development
errPHARMACEUTICS
IF5.5
err2022-01-13
err3
errOAAI
errMiranda, Claudia; Ruiz-Picazo, Alejandro; Pomares, Paula; Gonzalez-Alvarez, Isabel; Bermejo, Marival; Gonzalez-Alvarez, Marta; Avdeef, Alex; Cabrera-Perez, Miguel-Angel
err分享
err收藏
Is equilibrium slurry pH a good surrogate for solid surface pH during drug dissolution?
errEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF4.7
err2022-01-01
err8
errOAAI
errUekusa, Taiga; Avdeef, Alex; Sugano, Kiyohiko
err分享
err收藏
Salt Solubility and Disproportionation - Uses and Limitations of Equations for pHmax and the In-silico Prediction of pHmax盐的溶解度和歧化-pHmax方程式的使用和局限性以及pHmax的计算机预测
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2022-01-01
err13
errOAAI
errAvdeef, Alex; Sugano, Kiyohiko
err分享
err收藏
The Critical Role of Passive Permeability in Designing Successful Drugs被动渗透性在设计成功药物中的关键作用
errCHEMMEDCHEM
IF3.4
err2020-09-10
err76
PREAI
errDi, Li; Artursson, Per; Avdeef, Alex; Benet, Leslie Z.; Houston, J. Brian; Kansy, Manfred; Kerns, Edward H.; Lennernaes, Hans; Smith, Dennis A.; Sugano, Kiyohiko
err分享
err收藏
Do you know your r2?
errADMET AND DMPK
IF4.3
err2020-08-30
err16
errOAAI
errAvdeef, Alex
err分享
err收藏
Findings of the Second Challenge to Predict Aqueous Solubility
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2020-08-14
err43
PREAI
errLlinas, Antonio; Oprisiu, Ioana; Avdeef, Alex
err分享
err收藏
Potentiometric CheqSol and standardized shake-flask solubility methods are complimentary tools in physicochemical profiling电位法CheqSol和标准化摇瓶溶解度法是理化分析中的补充工具
errEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF4.7
err2020-05-01
err0
errOAAI
errLucero-Borja, Diego; Subirats, Xavier; Barbas, Rafael; Prohens, Rafel; Avdeef, Alex; Rafols, Clara
err分享
err收藏
Can small drugs predict the intrinsic aqueous solubility of 'beyond Rule of 5' big drugs?
errADMET AND DMPK
IF4.3
err2020-04-25
err11
errOAAI
errAvdeef, Alex; Kansy, Manfred
err分享
err收藏
Prediction of aqueous intrinsic solubility of druglike molecules using Random Forest regression trained with Wiki-pS0 database
errADMET AND DMPK
IF4.3
err2020-03-04
err44
errOAAI
errAvdeef, Alex
err分享
err收藏
Solubility Challenge Revisited after Ten Years, with Multilab Shake-Flask Data, Using Tight (SD ∼ 0.17 log) and Loose (SD ∼ 0.62 log) Test Sets
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2019-05-01
err45
PREAI
errLlinas, Antonio; Avdeef, Alex
err分享
err收藏
Solubility-pH profile of desipramine hydrochloride in saline phosphate buffer: Enhanced solubility due to drug-buffer aggregates
errEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF4.7
err2019-05-01
err28
errOAAI
errMarkovic, Olivera S.; Pesic, Milos P.; Shah, Ankita, V; Serajuddin, Abu T. M.; Verbic, Tatjana Z.; Avdeef, Alex
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
K
Kenneth N. Raymond
H 指数: 107 · 论文数: 800
P
Per Artursson
H 指数: 94 · 论文数: 374
B
Beate I. Escher
H 指数: 91 · 论文数: 510
L
Leslie Z. Benet
H 指数: 89 · 论文数: 628
J
Jennifer Dressman
H 指数: 85 · 论文数: 402
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