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J

Jan Rekowski

The Institute of Cancer Research
H指数:24
被引数:2,191

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Corrigendum to “B7-H3 as a Therapeutic Target in Advanced Prostate Cancer” [European Urology 83 (2023) 224–238

勘误：“B7-H3 作为晚期前列腺癌的治疗靶点” [欧洲泌尿外科杂志 83 (2023) 224–238]

European Urology
IF25.2
2026-08-070
OAAI
Christina Guo; Ines Figueiredo; Bora Gurel; Antje Neeb; George Seed; Mateus Crespo; Suzanne Carreira; Jan Rekowski; Lorenzo Buroni; Jon Welti; Denisa Bogdan; Lewis Gallagher; Adam Sharp; Maria D. Fenor de la Maza; Pasquale Rescigno; Daniel Westaby; Khobe Chandran; Ruth Riisnaes; Ana Ferreira; Susana Miranda
An Open-label, Phase 1 Dose-finding Study of Single-agent IMU-935, a Novel RORγ/RORγt Inverse Agonist, in Patients with Progressive Metastatic Castration-resistant Prostate Cancer

一项开放标签、I期剂量探索研究，评估单药IMU-935（一种新型RORγ/RORγt反向激动剂）在进展性转移性去势抵抗性前列腺癌患者中的疗效。

European Urology Oncology
IF9.3
2026-03-110
OAAI
Rafael Grochot; Christina Guo; Suzanne Carreira; Mateus Crespo; Jon Welti; Susana Miranda; Ines Figueiredo; Claudia Bertan; Jan Rekowski; Wei Yuan; Nina Tunariu; Katarzyna Abramowicz; Ana Ferreira; Ruth Riisnaes; Antje Neeb; Bora Gurel; Maria de Los Dolores Fenor de la Maza; Khobe Chandran; Juliet Carmichael; Daniel Westaby
Chromosomal instability in circulating tumor cells and cabazitaxel resistance in metastatic castration-resistant prostate cancer

循环肿瘤细胞中的染色体不稳定性与转移性去势抵抗性前列腺癌中的卡巴他赛耐药性

JCI Insight
IF6.1
2025-12-220
OA
Longoria, Ossian; Rekowski, Jan; Gupta, Santosh; Beije, Nick; Pantel, Klaus; Efstathiou, Eleni; Sternberg, Cora; Castellano, Daniel; Fizazi, Karim; Tombal, Bertrand; Sharp, Adam; Sartor, Oliver; Mace, Sandrine; Geffriaud-Ricouard, Christine; Wenstrup, Richard; De Wit, Ronald; De Bono, Johann
Developing therapeutic strategies to target MCL1 and BCLXL in lethal prostate cancer

开发针对MCL1和BCLXL的致死性前列腺癌的治疗策略

iScience
IF4.1
2025-11-100
OAAI
Daniel Westaby; Juan M. Jiménez-Vacas; Ines Figueiredo; Jonathan Welti; Bora Gurel; Denisa Bogdan; Lorenzo Buroni; Antje J. Neeb; Jan Rekowski; Ana Padilha; Souvik Das; Joe Taylor; Wanting Zeng; Nick Waldron; Thomas Goldsmith; Emily Hobern; Florian Gabel; Nicole Pandell; Susana Miranda; Maryou B. Lambros
Elucidating molecularly stratified single agent, and combination, therapeutic strategies targeting MCL1 for lethal prostate cancer

阐明靶向MCL1的分子分层单药及联合治疗策略，以治疗致命性前列腺癌

Nature Communications
IF15.7
2025-10-080
OAAI
Juan M. Jiménez-Vacas; Daniel Westaby; Ines Figueiredo; Alexis De Haven Brandon; Ana Padilha; Wei Yuan; George Seed; Denisa Bogdan; Bora Gurel; Claudia Bertan; Susana Miranda; Maryou Lambros; Antonio J. Montero-Hidalgo; Ilsa Coleman; Ivan Pak Lok Yu; Lorenzo Buroni; Wanting Zeng; Antje J. Neeb; Jon Welti; Jan Rekowski; Roberta Paravati; Florian Gabel; Nicole Pandell; Ana Ferreira; Mateus Crespo; Ruth Riisnaes; Souvik Das; Joe Taylor; Nick Waldron; Emily Hobern; Melanie Valenti; Jian Ning; Ilona Bernett; Kate Liodaki; Thomas Persse; Patricia Galipeau; Scott Wilkinson; Shana Y. Trostel; Fatima Karzai; Cindy H. Chau; Erica L. Beatson; Xiaohu Zhang; Carleen Klumpp-Thomas; Andreas Varkaris; Raul M. Luque; Amanda Swain; Florence Raynaud; Nathan A. Lack; Craig J. Thomas; Gavin Ha; William D. Figg; Marco Bezzi; Adam G. Sowalsky; Peter S. Nelson; Suzanne Carreira; Steven P. Balk; Johann S. de Bono; Adam Sharp
Defactinib with avutometinib in patients with solid tumors: the phase 1 FRAME trial

德法替尼联合阿瓦替尼治疗实体瘤患者: 1期框架试验

Nature Medicine
IF50
2025-06-270
OAAI
Susana Banerjee; Matthew G. Krebs; Alastair Greystoke; Alvaro Ingles Garces; Vicky Sanchez Perez; Angelika Terbuch; Rajiv Shinde; Reece Caldwell; Rafael Grochot; Mahtab Rouhifard; Ruth Ruddle; Bora Gurel; Karen Swales; Nina Tunariu; Toby Prout; Mona Parmar; Stefan Symeonides; Jan Rekowski; Christina Yap; Adam Sharp; Alec Paschalis; Juanita Lopez; Anna Minchom; Johann Sebastian de Bono; Udai Banerji
BCL2 expression is enriched in advanced prostate cancer with features of lineage plasticity
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-09-170
OAAI
Westaby, Daniel; Jimenez-Vaca, Juan M.; Figueiredo, Ines; Rekowski, Jan; Pettinger, Claire; Gurel, Bora; Lundberg, Arian; Bogdan, Denisa; Buroni, Lorenzo; Neeb, Antje; Padilha, Ana; Taylor, Joe; Zeng, Wanting; Das, Souvik; Hobern, Emily; Riisnaes, Ruth; Crespo, Mateus; Miranda, Susana; Ferreira, Ana; Hanratty, Brian P.; Rodrigues, Daniel Nava; Bertan, Claudia; Seed, George; Maza, Maria de Los Dolores Fenor de La; Guo, Christina; Carmichael, Juliet; Grochot, Rafael; Chandran, Khobe; Stavridi, Anastasia; Varkaris, Andreas; Stylianou, Nataly; Hollier, Brett G.; Tunariu, Nina; Balk, Steven P.; Carreira, Suzanne; Yuan, Wei; Nelson, Peter S.; Corey, Eva; Haffner, Michael; de Bono, Johann; Sharp, Adam
RNASEH2B loss and PARP inhibition in advanced prostate cancer
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-06-040
OAAI
Carmichael, Juliet; Figueiredo, Ines; Gurel, Bora; Beije, Nick; Yuan, Wei; Rekowski, Jan; Seed, George; Carreira, Suzanne; Bertan, Claudia; de La Maza, Maria de Los Dolores Fenor; Chandran, Khobe; Neeb, Antje; Welti, Jon; Gallagher, Lewis; Bogdan, Denisa; Crespo, Mateus; Riisnaes, Ruth; Ferreira, Ana; Miranda, Susana; Lu, Jinqiu; Shen, Michael M.; Hall, Emma; Porta, Nuria; Westaby, Daniel; Guo, Christina; Grochot, Rafael; Lord, Christopher J.; Mateo, Joaquin; Sharp, Adam; de Bono, Johann
Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer
MOLECULAR CANCER THERAPEUTICS
IF5.5
2024-02-272
OAAI
Neeb, Antje; Figueiredo, Ines; Bogdan, Denisa; Cato, Laura; Stober, Jutta; Jimenez-Vacas, Juan M.; Gourain, Victor; Lee, Irene I.; Seeger, Rebecca; Muhle-Goll, Claudia; Gurel, Bora; Welti, Jonathan; Nava Rodrigues, Daniel; Rekowski, Jan; Qiu, Xintao; Jiang, Yija; Di Micco, Patrizio; Mateos, Borja; Bielskute, Stase; Riisnaes, Ruth; Ferreira, Ana; Miranda, Susana; Crespo, Mateus; Buroni, Lorenzo; Ning, Jian; Carreira, Suzanne; Braese, Stefan; Jung, Nicole; Graessle, Simone; Swain, Amanda; Salvatella, Xavier; Plymate, Stephen R.; Al-Lazikani, Bissan; Long, Henry W.; Yuan, Wei; Brown, Myles; Cato, Andrew C. B.; de Bono, Johann S.; Sharp, Adam
Development and Validation of a New BAG-1L-Specific Antibody to Quantify BAG-1L Protein Expression in Advanced Prostate Cancer

一种新的BAG-1L-Specific抗体的开发和验证，以量化晚期前列腺癌中的BAG-1L蛋白表达

LABORATORY INVESTIGATION
IF4.2
2023-11-011
OAAI
Neeb, Antje; Figueiredo, Ines; Gurel, Bora; Rodrigues, Daniel Nava; Rekowski, Jan; Riisnaes, Ruth; Ferreira, Ana; Miranda, Susana; Crespo, Mateus; Westaby, Daniel; de La Maza, Maria de Los Dolores Fenor; Guo, Christina; Carmichael, Juliet; Grochot, Rafael; Tunariu, Nina; Cato, Andrew C. B.; Plymate, Stephen R.; de Bono, Johann S.; Sharp, Adam
Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance

提高早期剂量发现临床试验的报告质量和影响: CONSORT剂量发现扩展 (CONSORT-DEFINE) 指南

BMJ-BRITISH MEDICAL JOURNAL
IF42.7
2023-10-209
OAAI
Yap, Christina; Solovyeva, Olga; de Bono, Johann; Rekowski, Jan; Patel, Dhrusti; Jaki, Thomas; Mander, Adrian; Evans, Thomas R. Jeffry; Peck, Richard; Hayward, Kathryn S.; Hopewell, Sally; Ursino, Moreno; Rantell, Khadija Rerhou; Calvert, Melanie; Lee, Shing; Kightley, Andrew; Ashby, Deborah; Chan, An-Wen; Garrett-Mayer, Elizabeth; Isaacs, John; Golub, Robert; Kholmanskikh, Olga; Richards, Dawn; Boix, Oliver; Matcham, James; Seymour, Lesley; Ivy, S. Percy; Marshall, Lynley, V; Hommais, Antoine; Liu, Rong; Tanaka, Yoshiya; Berlin, Jordan; Espinasse, Aude; Dimairo, Munyaradzi; Weir, Christopher J.
Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance

提高早期剂量发现临床试验方案的质量和影响: 精神剂量发现扩展 (SPIRIT-DEFINE) 指南

BMJ-BRITISH MEDICAL JOURNAL
IF42.7
2023-10-207
OA
Yap, Christina; Rekowski, Jan; Ursino, Moreno; Solovyeva, Olga; Patel, Dhrusti; Dimairo, Munyaradzi; Weir, Christopher J.; Chan, An-Wen; Jaki, Thomas; Mander, Adrian; Evans, Thomas R. Jeffry; Peck, Richard; Hayward, Kathryn S.; Calvert, Melanie; Rantell, Khadija Rerhou; Lee, Shing; Kightley, Andrew; Hopewell, Sally; Ashby, Deborah; Garrett-Mayer, Elizabeth; Isaacs, John; Golub, Robert; Kholmanskikh, Olga; Richards, Dawn P.; Boix, Oliver; Matcham, James; Seymour, Lesley; Ivy, S. Percy; Marshall, Lynley, V; Hommais, Antoine; Liu, Rong; Tanaka, Yoshiya; Berlin, Jordan; Espinasse, Aude; de Bono, Johann
Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance

靶向髓系趋化逆转前列腺癌治疗耐药

Nature
IF48.5
2023-10-160
OAAI
Christina Guo; Adam Sharp; Bora Gurel; Mateus Crespo; Ines Figueiredo; Suneil Jain; Ursula Vogl; Jan Rekowski; Mahtab Rouhifard; Lewis Gallagher; Wei Yuan; Suzanne Carreira; Khobe Chandran; Alec Paschalis; Ilaria Colombo; Anastasios Stathis; Claudia Bertan; George Seed; Jane Goodall; Florence Raynaud; Ruth Ruddle; Karen E. Swales; Jason Malia; Denisa Bogdan; Crescens Tiu; Reece Caldwell; Caterina Aversa; Ana Ferreira; Antje Neeb; Nina Tunariu; Daniel Westaby; Juliet Carmichael; Maria Dolores Fenor de la Maza; Christina Yap; Ruth Matthews; Hannah Badham; Toby Prout; Alison Turner; Mona Parmar; Holly Tovey; Ruth Riisnaes; Penny Flohr; Jesus Gil; David Waugh; Shaun Decordova; Anna Schlag; Bianca Calì; Andrea Alimonti; Johann S. de Bono
Circulating tumor DNA (ctDNA) low pass whole genome sequencing (lpWGS) studies identify genomic alterations associating with taxane outcomes in prospective phase III taxane trials for metastatic castration resistant prostate cancer (mCRPC) sufferers
ANNALS OF ONCOLOGY
IF65.4
2023-10-010
OA
Seed, G.; Greening, S.; Goodall, J.; Rekowski, J.; Christova, R.; Mehra, N.; Eisenberger, M.; Fizazi, K.; Tombal, B.; Wuelfing, C.; Sternberg, C. N.; Gauna, D. E. Castellano; Oudard, S.; Sartor, O.; Geffriaud-Ricouard, C.; Chadjaa, M.; Mace, S.; Carreira, S.; Yuan, W.; de Bono, J. S.
BCL2 expression is enriched in AR-independent advanced prostate cancer
CANCER RESEARCH
IF16.6
2023-06-021
PRE
Westaby, Daniel; Jimenez-Vacas, Juan M.; Figueiredo, Ines; Pettinger, Claire; Gurel, Bora; Bogdan, Denisa; Rekowski, Jan; Buroni, Lorenzo; Neeb, Antje; Riisnaes, Ruth; Crespo, Mateus; Miranda, Susana; Ferreira, Ana; Rodrigues, Daniel Nava; Seed, George; Bertan, Claudia; de la Maza, Maria de los Dolores Fenor; Guo, Christina; Carmichael, Juliet; Grochot, Rafael; Chandran, Khobe; Varkaris, Andreas; Balk, Steven P.; Yuan, Wei; Carreira, Suzanne; Nelson, Peter S.; Haffner, Michael; Corey, Eva; de Bono, Johann; Sharp, Adam

研究方向

暂未获取到该数据
J
Johann S. de Bono
H 指数:160论文数:2,491被引数:13.4万
B
Bora Gürel
H 指数:37论文数:417被引数:7,020
A
Adam Sharp
H 指数:41论文数:495被引数:6,063
S
Suzanne Carreira
H 指数:49论文数:437被引数:1.4万
A
Antje Neeb
H 指数:31论文数:315被引数:4,331
S
Susana Miranda
H 指数:44论文数:341被引数:1.4万
M
Mateus Crespo
H 指数:41论文数:365被引数:5,760
G
George Seed
H 指数:28论文数:157被引数:6,576
R
Ruth Riisnaes
H 指数:41论文数:442被引数:9,970
I
Ines Figueiredo
H 指数:39论文数:288被引数:7,863