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Nuclear poly(A)-binding protein and nucleolin utilize their RNA recognition motifs to read PAR chains 核多聚(A)结合蛋白和核仁素利用它们的RNA识别基序来读取PAR链 Shi, Leilei; Dasovich, Morgan; Horton, John R.; Liu, Hongrui; Zhan, Qiansheng; Manickavinayaham, Swarnalatha; Jeter, Collene R.; Mixon, Isaiah J.; Zehrbach, Nicholas M.; Ishak, Charles A.; Yoon, Je-Hyun; Cheng, Xiaodong; Leung, Anthony K. L.; Bedford, Mark T. 分享 收藏
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Multimeric transcription factor BCL11A utilizes two zinc-finger tandem arrays to bind clustered short sequence motifs 多聚体转录因子BCL11A利用两个锌指串联阵列结合成簇的短序列基序 Horton, John R.; Yu, Meigen; Zhou, Jujun; Tran, Melody; Anakal, Rithvi R.; Lu, Yue; Blumenthal, Robert M.; Zhang, Xiaotian; Huang, Yun; Zhang, Xing; Cheng, Xiaodong 分享 收藏
Quinoline-based compounds can inhibit diverse enzymes that act on DNA Zhou, Jujun; Chen, Qin; Ren, Ren; Yang, Jie; Liu, Bigang; Horton, John R.; Chang, Caleb; Li, Chuxuan; Maksoud, Leora; Yang, Yifei; Rotili, Dante; Jain, Abhinav K.; Zhang, Xing; Blumenthal, Robert M.; Chen, Taiping; Gao, Yang; Valente, Sergio; Mai, Antonello; Cheng, Xiaodong 分享 收藏
Allometric scaling of preclinical dosimetry for the Nectin-4 miniprotein binders AKY-807 and AKY-1189 accurately predicts human absorbed dose to major organs Ramonaheng, K.; Qebetu, M.; Ndlovu, H.; Kabunda, J.; Mokoala, K.; Smith, L.; Swanepoel, C.; Davis, C.; Mathiba, R.; Singh, K.; Mathabe, K.; Khanyile, R.; Mashudu, M.; Makvandi, M.; Kovacs, J.; Horton, J.; Herrmann, K.; Sathekge, M. 分享 收藏
The ICF syndrome protein CDCA7 harbors a unique DNA binding domain that recognizes a CpG dyad in the context of a non-B DNA Hardikar, Swanand; Ren, Ren; Ying, Zhengzhou; Zhou, Jujun; Horton, John R.; Bramble, Matthew D.; Liu, Bin; Lu, Yue; Liu, Bigang; Della Coletta, Luis; Shen, Jianjun; Dan, Jiameng; Zhang, Xing; Cheng, Xiaodong; Chen, Taiping 分享 收藏
DNA sequence and chromatin differentiate sequence-specific transcription factor binding in the human malaria parasite Plasmodium falciparum Bonnell, Victoria A.; Zhang, Yuning; Brown, Alan S.; Horton, John; Josling, Gabrielle A.; Chiu, Tsu-Pei; Rohs, Remo; Mahony, Shaun; Gordan, Raluca; Llinas, Manuel 分享 收藏
Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga Zhou, Jujun; Horton, John R.; Kaur, Gundeep; Chen, Qin; Li, Xuwen; Mendoza, Fabian; Wu, Tao; Blumenthal, Robert M.; Zhang, Xing; Cheng, Xiaodong 分享 收藏
HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription (vol 54, 1417, 2022) Huang, Peng; Peslak, Scott A.; Ren, Ren; Khandros, Eugene; Qin, Kunhua; Keller, Cheryl A.; Giardine, Belinda; Bell, Henry W.; Lan, Xianjiang; Sharma, Malini; Horton, John R.; Abdulmalik, Osheiza; Chou, Stella T. T.; Shi, Junwei; Crossley, Merlin; Hardison, Ross C.; Cheng, Xiaodong; Blobel, Gerd A. 分享 收藏
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Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase Zhou, Jujun; Deng, Youchao; Iyamu, Iredia D.; Horton, John R.; Yu, Dan; Hajian, Taraneh; Vedadi, Masoud; Rotili, Dante; Mai, Antonello; Blumenthal, Robert M.; Zhang, Xing; Huang, Rong; Cheng, Xiaodong 分享 收藏
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Allosteric autoregulation of DNA binding via a DNA-mimicking protein domain: a biophysical study of ZNF410-DNA interaction using small angle X-ray scattering Kaur, Gundeep; Ren, Ren; Hammel, Michal; Horton, John R.; Yang, Jie; Cao, Yu; He, Chenxi; Lan, Fei; Lan, Xianjiang; Blobel, Gerd A.; Blumenthal, Robert M.; Zhang, Xing; Cheng, Xiaodong 分享 收藏
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence Zhou, Jujun; Horton, John R.; Menna, Martina; Fiorentino, Francesco; Ren, Ren; Yu, Dan; Hajian, Taraneh; Vedadi, Masoud; Mazzoccanti, Giulia; Ciogli, Alessia; Weinhold, Elmar; Hueben, Michael; Blumenthal, Robert M.; Zhang, Xing; Mai, Antonello; Rotili, Dante; Cheng, Xiaodong 分享 收藏
HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription Huang, Peng; Peslak, Scott A.; Ren, Ren; Khandros, Eugene; Qin, Kunhua; Keller, Cheryl A.; Giardine, Belinda; Bell, Henry W.; Lan, Xianjiang; Sharma, Malini; Horton, John R.; Abdulmalik, Osheiza; Chou, Stella T.; Shi, Junwei; Crossley, Merlin; Hardison, Ross C.; Cheng, Xiaodong; Blobel, Gerd A. 分享 收藏
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Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia Pappalardi, Melissa B.; Keenan, Kathryn; Cockerill, Mark; Kellner, Wendy A.; Stowell, Alexandra; Sherk, Christian; Wong, Kristen; Pathuri, Sarath; Briand, Jacques; Steidel, Michael; Chapman, Philip; Groy, Arthur; Wiseman, Ashley K.; McHugh, Charles F.; Campobasso, Nino; Graves, Alan P.; Fairweather, Emma; Werner, Thilo; Raoof, Ali; Butlin, Roger J.; Rueda, Lourdes; Horton, John R.; Fosbenner, David T.; Zhang, Cunyu; Handler, Jessica L.; Muliaditan, Morris; Mebrahtu, Makda; Jaworski, Jon-Paul; McNulty, Dean E.; Burt, Charlotte; Eberl, H. Christian; Taylor, Amy N.; Ho, Thau; Merrihew, Susan; Foley, Shawn W.; Rutkowska, Anna; Li, Mei; Romeril, Stuart P.; Goldberg, Kristin; Zhang, Xing; Kershaw, Christopher S.; Bantscheff, Marcus; Jurewicz, Anthony J.; Minthorn, Elisabeth; Grandi, Paola; Patel, Mehul; Benowitz, Andrew B.; Mohammad, Helai P.; Gilmartin, Aidan G.; Prinjha, Rab K.; Ogilvie, Donald; Carpenter, Christopher; Heerding, Dirk; Baylin, Stephen B.; Jones, Peter A.; Cheng, Xiaodong; King, Bryan W.; Luengo, Juan, I; Jordan, Allan M.; Waddell, Ian; Kruger, Ryan G.; McCabe, Michael T. 分享 收藏
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