Alaattin Şen - Publications, H-index & Citations

Alaattin Şen

Abdullah Gul University

21H指数

166论文数

1.5K被引数

收录论文 31

发表时间

Targeting cholinergic dysfunction and neuroinflammation through rationally designed Thieno[3,2-d]pyrimidine hybrids 靶向胆碱能功能障碍和神经炎症，通过合理设计的Thieno[3,2-d]pyrimidine杂化物

Bioorganic Chemistry

IF4.7

2026-03-19

PREAI

Feyzi Sinan Tokalı; Ozden Ozgun Acar; Yeliz Demir; Halil Şenol; Busra Acar; Furkan Çakır; Alaattin Sen

Design and synthesis of Polymethoxy Rhodanines as selective small-molecule candidates for breast cancers 多甲氧基硫代巴比妥酸的设计与合成及其作为乳腺癌选择性小分子候选物的应用

Journal of Molecular Structure

IF4.7

2026-02-14

PREAI

Feyzi Sinan Tokalı; Gurbet Çelik Turgut; Ayşe Merve Şenol; Pelin Tokalı; Furkan Çakır; Halil Şenol; Alaattin Şen

A Small Indole Derivative Isolated From Caper (Capparis ovata) as an Inducer of P53-Mediated Apoptosis in Prostate Cancer: Comprehensive In Vitro and In Silico Studies

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

IF2.8

2025-12-31

PREAI

Acar, Ozden Ozgun; Gazioglu, Isil; Oruc, Hatice; Kale, Elif; Senol, Halil; Topcu, Gulacti; Sen, Alaattin

A series of 4-thiomorpholinophenyl-thiosemicarbazones as cholinesterase inhibitors with anti-neuroblastoma effects 一系列4-噻吗啉基苯基-硫代半卡巴腙作为胆碱酯酶抑制剂，具有抗神经母细胞瘤效果

Bioorganic Chemistry

IF4.7

2025-12-09

PREAI

Hina Aftab; Furkan Çakır; Gurbet Çelik Turgut; Nastaran Sadeghian; Rima D. Alharthy; Parham Taslimi; Alaattin Şen; Magdi E.A. Zaki; Sobhi M. Gomha; Javid Hussain; Zahid Shafiq; Halil Şenol

Interaction of Inula viscosa (L.) Aiton with Iba1 via Rosmarinic Acid and Rutin: Insights from Computational Models and Biological Effects

CHEMISTRYSELECT

IF2

2025-10-29

PREAI

Aktas Pepe, Nihan; Acar, Busra; Ceylan Ekiz, Yagmur; Senol, Ayse Merve; Semiz, Gurkan; Sen, Alaattin; Celik Turgut, Gurbet

Synthesis, Characterization, and Comprehensive In Vitro and In Silico Evaluation of the Anti-Inflammatory Potential of Novel 1,2,3-Triazole–Arylidenehydrazide/Thiazolidinone Hybrids 合成、表征及对新型1,2,3-三唑-亚苄基酰肼/噻唑烷酮杂合物的抗炎潜力的全面体外和计算机模拟评价

Archiv der Pharmazie

IF3.6

2025-09-03

PREAI

Nihan Aktaş Pepe; Furkan Çakır; Tuğba Atalay; Büşra Acar; Gurbet Çelik Turgut; Alaattin Şen; Halil Şenol

Novel thiazolidinedione hybrids as cholinesterase inhibitors and targeting neuroblastoma: design, synthesis, in vitro and in silico biological evaluations 新型噻唑烷二酮杂合体作为胆碱酯酶抑制剂并靶向神经母细胞瘤：设计、合成、体外及计算机生物学评价

Bioorganic Chemistry

IF4.7

2025-08-14

PREAI

Gurbet Çelik Turgut; Furkan Çakır; Alaattin Şen; Feyzi Sinan Tokalı; Halil Şenol

Role of Long Non-Coding RNA X-Inactive-Specific Transcript (XIST) in Neuroinflammation and Myelination: Insights from Cerebral Organoids and Implications for Multiple Sclerosis 长链非编码RNA X-Inactive-Specific Transcript (XIST)在神经炎症和髓鞘化中的作用：来自脑类器官的见解及其对多发性硬化的意义

non coding rna research

IF0

2025-08-09

OAAI

Nihan Aktas Pepe; Busra Acar; Gozde Erturk Zararsiz; Serife Ayaz Guner; Alaattin Sen

Cinnamomum zeylanicum extract incorporated electrospun poly(lactic acid)/gelatin membrane as a new wound dressing 肉桂提取物复合的电纺聚乳酸/明胶膜作为新型伤口敷料

International Journal of Biological Macromolecules

IF8.5

2025-07-08

PREAI

Seray Zora Tarhan; Nihan Aktaş Pepe; Alaattin Şen; İsmail Alper İşoğlu

Amelioration potential of synthetic oxime chemical cores against multiple sclerosis and Alzheimer 's diseases: Evaluation in aspects of in silico and in vitro experiments

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2024-12-01

PREAI

Yilmaz, Anil; Koca, Murat; Ercan, Selami; Acar, Ozden Ozgun; Boga, Mehmet; Sen, Alaattin; Kurt, Adnan

Evaluation of Selected Plant Phenolics via Beta-Secretase-1 Inhibition, Molecular Docking, and Gene Expression Related to Alzheimer's Disease

PHARMACEUTICALS

IF4.8

2024-10-28

OAAI

Akyurek, Tugba Ucar; Orhan, Ilkay Erdogan; Deniz, F. Sezer Senol; Eren, Gokcen; Acar, Busra; Sen, Alaattin

Synthesis and Comprehensive in Vivo Activity Profiling of Olean-12-en-28-ol, 3β-Pentacosanoate in Experimental Autoimmune Encephalomyelitis: A Natural Remyelinating and Anti-Inflammatory Agent

JOURNAL OF NATURAL PRODUCTS

IF3.6

2023-01-04

OAAI

Senol, Halil; Ozgun-Acar, Ozden; Dag, Aydan; Eken, Ahmet; Guner, Huseyin; Aykut, Zaliha Gamze; Topcu, Gulacti; Sen, Alaattin

Biochemical, pharmacological, and toxicological attributes of caper (Capparis ovata) flowering buds and berries pickles

FOOD SCIENCE & NUTRITION

IF3.8

2022-07-30

OAAI

Ozgun-Acar, Ozden; Celik-Turgut, Gurbet; Guner, Huseyin; Sezer, Serdar; Sen, Alaattin

Triterpenoids and steroids isolated from Anatolian Capparis ovata and their activity on the expression of inflammatory cytokines

PHARMACEUTICAL BIOLOGY

IF4.8

2020-09-11

OAAI

Gazioglu, Isil; Semen, Sevcan; Acar, Ozden Ozgun; Kolak, Ufuk; Sen, Alaattin; Topcu, Gulacti

Role of cytochrome P450 polymorphisms and functions in development of ulcerative colitis

WORLD JOURNAL OF GASTROENTEROLOGY

IF5.4

2019-06-21

OAAI

Sen, Alaattin; Stark, Holger

Bioactive factors secreted by Bifidobacterium breve B-3 enhance barrier function in human intestinal Caco-2 cells

BENEFICIAL MICROBES

IF3.1

2019-02-08

PREAI

Kurose, Y.; Minami, J.; Sen, A.; Iwabuchi, N.; Abe, F.; Xiao, J.; Suzuki, T.

Tetrangomycin from Streptomyces stramineus CAH29 and its antimicrobial and cytotoxic activities

JOURNAL OF BIOTECHNOLOGY

IF3.9

2018-08-01

PREAI

Ozakin, Suleyman; Sen, Alaattin; Ince, Ebru

Stigmast-5,22-dien-3β-ol myristate isolated from Capparis ovata having anti-inflammatory and immunomodulatory actions could be of interest for use in multiple sclerosis

JOURNAL OF BIOTECHNOLOGY

IF3.9

2017-08-01

PREAI

Sen, Alaattin; Acar, Ozden Ozgun; Gazioglu, Isil; Kolak, Ufuk; Topcu, Gulacti

Computer design, synthesis, and bioactivity analyses of drugs like fingolimod used in the treatment of multiple sclerosis

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2017-01-01

PREAI

Turgut, Gurbet Celik; Doyduk, Dogukan; Yildirir, Yilmaz; Yavuz, Serkan; Akdemir, Atilla; Disli, Ali; Sen, Alaattin

Modulatory actions of o-coumaric acid on carcinogen-activating cytochrome P450 isozymes and the potential for drug interactions in human hepatocarcinoma cells o-香豆酸对人肝癌细胞中致癌物激活的细胞色素P450同工酶的调节作用和药物相互作用的潜力

PHARMACEUTICAL BIOLOGY

IF4.8

2015-04-16

OAAI

Sen, Alaattin; Terzioglu, Gulsum; Atmaca, Pelin; Celik, Gurbet; Ozgun, Ozden; Arslan, Sevki

研究方向