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Glucagon-like peptide-1 (GLP-1) receptor agonists in inflammatory bowel disease: mechanisms, clinical implications, and therapeutic potential Colwill, M.; Povlsen, S.; Pollok, R.; Patel, K.; Goodhand, J.; Ahmad, T.; Honap, S. 胰高血糖素样肽（GLP-1）受体激动剂在炎症性肠病中的应用：机制、临床意义和治疗潜力。J. Crohns Colitis 2025, 19, jjaf167. [Google Scholar] [CrossRef] Colwill, Michael; Povlsen, Sebastian; Pollok, Richard; Patel, Kamal; Goodhand, James; Ahmad, Tariq; Honap, Sailish 分享 收藏
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Mechanisms and management of loss of response to anti-TNF therapy for patients with Crohn's disease: 3-year data from the prospective, multicentre PANTS cohort study Chanchlani, Neil; Lin, Simeng; Bewshea, Claire; Hamilton, Benjamin; Thomas, Amanda; Smith, Rebecca; Roberts, Christopher; Bishara, Maria; Nice, Rachel; Lees, Charlie W.; Sebastian, Shaji; Irving, Peter M.; Russell, Richard K.; McDonald, Timothy J.; Goodhand, James R.; Ahmad, Tariq; Kennedy, Nicholas A. 分享 收藏
A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn's disease (PROFILE): a multicentre, open-label randomised controlled trial Noor, Nurulamin M.; Lee, James C.; Bond, Simon; Dowling, Francis; Brezina, Biljana; Patel, Kamal, V; Ahmad, Tariq; Banim, Paul J.; Berrill, James W.; Cooney, Rachel; Negro, Juan De La Revilla; de Silva, Shanika; Din, Shahida; Durai, Dharmaraj; Gordon, John N.; Irving, Peter M.; Johnson, Matthew; Kent, Alexandra J.; Kok, Klaartje B.; Moran, Gordon W.; Mowat, Craig; Patel, Pritash; Probert, Chris S.; Raine, Tim; Saich, Rebecca; Seward, Abigail; Sharpstone, Dan; Smith, Melissa A.; Subramanian, Sreedhar; Upponi, Sara S.; Wiles, Alan; Williams, Horace R. T.; van den Brink, Gijs R.; Vermeire, Severine; Jairath, Vipul; D'Haens, Geert R.; McKinney, Eoin F.; Lyons, Paul A.; Lindsay, James; Kennedy, Nicholas A.; Smith, Kenneth G. C.; Parkes, Miles 分享 收藏
Antibody Responses to Influenza Vaccination are Diminished in Patients With Inflammatory Bowel Disease on Infliximab or Tofacitinib 使用英夫利昔单抗或托法替尼的炎症性肠病患者对流感疫苗的抗体反应减弱 Liu, Zhigang; Alexander, James L.; Eng, Kai Yee; Ibraheim, Hajir; Anandabaskaran, Sulak; Saifuddin, Aamir; Constable, Laura; Seoane, Rocio Castro; Bewshea, Claire; Nice, Rachel; D'Mello, Andrea; Jones, Gareth R.; Balarajah, Sharmili; Fiorentino, Francesca; Sebastian, Shaji; Irving, Peter M.; Hicks, Lucy C.; Williams, Horace R. T.; Kent, Alexandra J.; Linger, Rachel; Parkes, Miles; Kok, Klaartje; Patel, Kamal, V; Teare, Julian P.; Altmann, Daniel M.; Boyton, Rosemary J.; Hart, Ailsa L.; Lees, Charlie W.; Goodhand, James R.; Kennedy, Nicholas A.; Pollock, Katrina M.; Ahmad, Tariq; Powell, Nick 分享 收藏
Neutralising antibody responses against SARS-CoV-2 Omicron BA.4/5 and wild-type virus in patients with inflammatory bowel disease following three doses of COVID-19 vaccine (VIP): a prospective, multicentre, cohort study 炎症性肠病患者在三剂新型冠状病毒肺炎疫苗 (VIP) 后中和针对SARS-CoV-2 Omicron BA.4/5和野生型病毒的抗体反应: 一项前瞻性、多中心、队列研究 Liu, Zhigang; Alexander, James L.; Le, Kaixing; Zhou, Xin; Ibraheim, Hajir; Anandabaskaran, Sulak; Saifuddin, Aamir; Lin, Kathy Weitung; McFarlane, Leon R.; Constable, Laura; Seoane, Rocio Castro; Anand, Nikhil; Bewshea, Claire; Nice, Rachel; D'Mello, Andrea; Jones, Gareth R.; Balarajah, Sharmili; Fiorentino, Francesca; Sebastian, Shaji; Irving, Peter M.; Hicks, Lucy C.; Williams, Horace R. T.; Kent, Alexandra J.; Linger, Rachel; Parkes, Miles; Kok, Klaartje; Patel, Kamal V.; Teare, Julian P.; Altmann, Daniel M.; Boyton, Rosemary J.; Hart, Ailsa L.; Lees, Charlie W.; Goodhand, James R.; Kennedy, Nicholas A.; Pollock, Katrina M.; Ahmad, Tariq; Powell, Nick 分享 收藏
Baseline Expression of Immune Gene Modules in Blood is Associated With Primary Response to Anti-TNF Therapy in Crohn's Disease Patients Bai, Benjamin Y. H.; Reppell, Mark; Smaoui, Nizar; Waring, Jeffrey F.; Pivorunas, Valerie; Guay, Heath; Lin, Simeng; Chanchlani, Neil; Bewshea, Claire; Goodhand, James R.; Kennedy, Nicholas A.; Ahmad, Tariq; Anderson, Carl A. 分享 收藏
Whole Blood DNA Methylation Changes Are Associated with Anti-TNF Drug Concentration in Patients with Crohn's Disease 克罗恩病患者全血DNA甲基化改变与抗TNF药物浓度相关 Lin, Simeng; Hannon, Eilis; Reppell, Mark; Waring, Jeffrey F.; Smaoui, Nizar; Pivorunas, Valerie; Guay, Heath; Chanchlani, Neil; Bewshea, Claire; Bai, Benjamin Y. H.; Kennedy, Nicholas A.; Goodhand, James R.; Mill, Jonathan; Ahmad, Tariq 分享 收藏
Prevalence of NUDT15 Genetic Variants and Incidence of Thiopurine-induced Leukopenia in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis 炎症性肠病中NUDT15基因变异的患病率和硫嘌呤诱导的白细胞减少症的发生率: 系统回顾和荟萃分析 Yu, Natalie; Sriranganathan, Danujan; Walker, Gareth J.; Sazonovs, Aleksejs; Wilding, Helen; Roberts, Christopher; Kennedy, Nicholas A.; Ahmad, Tariq; Boyapati, Ray K.; Ding, Nik S.; Segal, Jonathan P. 分享 收藏
Neutralising antibody potency against SARS-CoV-2 wild- type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study Liu, Zhigang; Le, Kaixing; Zhou, Xin; Alexander, James L.; Lin, Simeng; Bewshea, Claire; Chanchlani, Neil; Nice, Rachel; McDonald, Timothy J.; Lamb, Christopher A.; Sebastian, Shaji; Kok, Klaartje; Lees, Charlie W.; Hart, Ailsa L.; Pollok, Richard C.; Boyton, Rosemary J.; Altmann, Daniel M.; Pollock, Katrina M.; Goodhand, James R.; Kennedy, Nicholas A.; Ahmad, Tariq; Powell, Nick 分享 收藏
The gut microbiota and metabolome are associated with diminished COVID-19 vaccine-induced antibody responses in immunosuppressed inflammatory bowel disease patients Alexander, James L.; Mullish, Benjamin H.; Danckert, Nathan P.; Liu, Zhigang; Olbei, Marton L.; Saifuddin, Aamir; Torkizadeh, Melissa; Ibraheim, Hajir; Blanco, Jesus Miguens; Roberts, Lauren A.; Bewshea, Claire M.; Nice, Rachel; Lin, Simeng; Prabhudev, Hemanth; Sands, Caroline; Horneffer-van der Sluis, Verena; Lewis, Matthew; Sebastian, Shaji; Lees, Charlie W.; Teare, Julian P.; Hart, Ailsa; Goodhand, James R.; Kennedy, Nicholas A.; Korcsmaros, Tamas; Marchesi, Julian R.; Ahmad, Tariq; Powell, Nick 分享 收藏
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COVID-19 vaccine-induced antibody and T-cell responses in immunosuppressed patients with inflammatory bowel disease after the third vaccine dose (VIP): a multicentre, prospective, case-control study 免疫抑制的炎症性肠病患者在第三次疫苗剂量 (VIP) 后新型冠状病毒肺炎疫苗诱导的抗体和T细胞反应: 一项多中心，前瞻性，病例对照研究 Alexander, James L.; Liu, Zhigang; Sandoval, Diana Munoz; Reynolds, Catherine; Ibraheim, Hajir; Anandabaskaran, Sulak; Saifuddin, Aamir; Seoane, Rocio Castro; Anand, Nikhil; Nice, Rachel; Bewshea, Claire; D'Mello, Andrea; Constable, Laura; Jones, Gareth R.; Balarajah, Sharmili; Fiorentino, Francesca; Sebastian, Shaji; Irving, Peter M.; Hicks, Lucy C.; Williams, Horace R. T.; Kent, Alexandra J.; Linger, Rachel; Parkes, Miles; Kok, Klaartje; Patel, Kamal V.; Teare, Julian P.; Altmann, Daniel M.; Goodhand, James R.; Hart, Ailsa L.; Lees, Charlie W.; Boyton, Rosemary J.; Kennedy, Nicholas A.; Ahmad, Tariq; Powell, Nick 分享 收藏
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility 大规模测序鉴定与克罗恩病易感性相关的多个基因和罕见变异 Sazonovs, Aleksejs; Stevens, Christine R.; Venkataraman, Guhan R.; Yuan, Kai; Avila, Brandon; Abreu, Maria T.; Ahmad, Tariq; Allez, Matthieu; Ananthakrishnan, Ashwin N.; Atzmon, Gil; Baras, Aris; Barrett, Jeffrey C.; Barzilai, Nir; Beaugerie, Laurent; Beecham, Ashley; Bernstein, Charles N.; Bitton, Alain; Bokemeyer, Bernd; Chan, Andrew; Chung, Daniel; Cleynen, Isabelle; Cosnes, Jacques; Cutler, David J.; Daly, Allan; Damas, Oriana M.; Datta, Lisa W.; Dawany, Noor; Devoto, Marcella; Dodge, Sheila; Ellinghaus, Eva; Fachal, Laura; Farkkila, Martti; Faubion, William; Ferreira, Manuel; Franchimont, Denis; Gabriel, Stacey B.; Ge, Tian; Georges, Michel; Gettler, Kyle; Giri, Mamta; Glaser, Benjamin; Goerg, Siegfried; Goyette, Philippe; Graham, Daniel; Hamalainen, Eija; Haritunians, Talin; Heap, Graham A.; Hiltunen, Mikko; Hoeppner, Marc; Horowitz, Julie E.; Irving, Peter; Iyer, Vivek; Jalas, Chaim; Kelsen, Judith; Khalili, Hamed; Kirschner, Barbara S.; Kontula, Kimmo; Koskela, Jukka T.; Kugathasan, Subra; Kupcinskas, Juozas; Lamb, Christopher A.; Laudes, Matthias; Levesque, Chloe; Levine, Adam P.; Lewis, James D.; Liefferinckx, Claire; Loescher, Britt-Sabina; Louis, Edouard; Mansfield, John; May, Sandra; McCauley, Jacob L.; Mengesha, Emebet; Mni, Myriam; Moayyedi, Paul; Moran, Christopher J.; Newberry, Rodney D.; O'Charoen, Sirimon; Okou, David T.; Oldenburg, Bas; Ostrer, Harry; Palotie, Aarno; Paquette, Jean; Pekow, Joel; Peter, Inga; Pierik, Marieke J.; Ponsioen, Cyriel Y.; Pontikos, Nikolas; Prescott, Natalie; Pulver, Ann E.; Rahmouni, Souad; Rice, Daniel L.; Saavalainen, Paivi; Sands, Bruce; Sartor, R. Balfour; Schiff, Elena R.; Schreiber, Stefan; Schumm, L. Philip; Segal, Anthony W.; Seksik, Philippe; Shawky, Rasha; Sheikh, Shehzad Z.; Silverberg, Mark S.; Simmons, Alison; Skeiceviciene, Jurgita; Sokol, Harry; Solomonson, Matthew; Somineni, Hari; Sun, Dylan; Targan, Stephan; Turner, Dan; Uhlig, Holm H.; van der Meulen, Andrea E.; Vermeire, Severine; Verstockt, Sare; Voskuil, Michiel D.; Winter, Harland S.; Young, Justine; Duerr, Richard H.; Franke, Andre; Brant, Steven R.; Cho, Judy; Weersma, Rinse K.; Parkes, Miles; Xavier, Ramnik J.; Rivas, Manuel A.; Rioux, John D.; McGovern, Dermot P. B.; Huang, Hailiang; Anderson, Carl A.; Daly, Mark J. 分享 收藏
Implications for sequencing of biologic therapy and choice of second anti-TNF in patients with inflammatory bowel disease: Results from the IMmunogenicity to Second Anti-TNF therapy (IMSAT) therapeutic drug monitoring study Chanchlani, Neil; Lin, Simeng; Auth, Marcus K.; Lee, Chai Leng; Robbins, Helena; Looi, Shi; Murugesan, Senthil, V; Riley, Tom; Preston, Cathryn; Stephenson, Sophie; Cardozo, Wendy; Sonwalkar, Sunil A.; Allah-Ditta, Mohammed; Mansfield, Lynne; Durai, Dharmaraj; Baker, Mark; London, Ian; London, Emily; Gupta, Sanjay; Di Mambro, Alex; Murphy, Aisling; Gaynor, Edward; Jones, Kelsey D. J.; Claridge, Andrew; Sebastian, Shaji; Ramachandran, Sankaranarayanan; Selinger, Christian P.; Borg-Bartolo, Simon P.; Knight, Paul; Sprakes, Michael B.; Burton, Julie; Kane, Patricia; Lupton, Stephanie; Fletcher, Aimee; Gaya, Daniel R.; Colbert, Roghan; Seenan, John Paul; MacDonald, Jonathan; Lynch, Lucy; McLachlan, Iain; Shields, Stephanie; Hansen, Richard; Gervais, Lisa; Jere, Mwansa; Akhtar, Muhammad; Black, Karen; Henderson, Paul; Russell, Richard K.; Lees, Charlie W.; Derikx, Lauranne A. A. P.; Lockett, Melanie; Betteridge, Frederica; De Silva, Aminda; Hussenbux, Arif; Beckly, John; Bendall, Oliver; Hart, James W.; Thomas, Amanda; Hamilton, Ben; Gordon, Claire; Chee, Desmond; McDonald, Timothy J.; Nice, Rachel; Parkinson, Marian; Gardner-Thorpe, Helen; Butterworth, Jeff R.; Javed, Asima; Al-Shakhshir, Sarah; Yadagiri, Rekha; Maher, Sebrene; Pollok, Richard C. G.; Ng, Tze; Appiahene, Priscilla; Donovan, Fiona; Lok, James; Chandy, Rajiv; Jagdish, Reema; Baig, Daniyal; Mahmood, Zahid; Marsh, Liane; Moss, Allison; Abdulgader, Amin; Kitchin, Angus; Walker, Gareth J.; George, Becky; Lim, Yuen-Hui; Gulliver, James; Bloom, Stuart; Theaker, Holly; Carlson, Sean; Cummings, J. R. Fraser; Livingstone, Robert; Beale, Amanda; Carter, Josiah O.; Bell, Andrew; Coulter, Archibald; Snook, Jonathon; Stone, Helen; Kennedy, Nicholas A.; Goodhand, James R.; Ahmad, Tariq 分享 收藏
Understanding anti-TNF treatment failure: Does serum triiodothyronine-to-thyroxine (T3/T4) ratio predict therapeutic outcome to anti-TNF therapies in biologic-naive patients with active luminal Crohn's disease? Lin, Simeng; Chanchlani, Neil; Carbery, Isabel; Janjua, Malik; Nice, Rachel; McDonald, Timothy J.; Bewshea, Claire; Kennedy, Nicholas A.; Ahmad, Tariq; Selinger, Christian P.; Goodhand, James R. 分享 收藏
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