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E

Eija Pirinen

University of Oulu
H指数:33
被引数:7,723

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Human brown fat metabolism associates with systemic branched-chain amino acids homeostasis

人类棕色脂肪代谢与系统性支链氨基酸稳态相关

Molecular Metabolism
IF6.6
2026-09-010
PRE
U-Din, Mueez; Acosta, Francisco M.; Saari, Teemu; Laaksonen, Vanessa D. de Mello; van der Kolk, Birgitta W.; Monfort-Pires, Milena; Clemente-Postigo, Mercedes; Niemi, Tarja; Taittonen, Markku; Tuomainen, Marjo; Fromme, Tobias; Lehtonen, Marko; Kristiansen, Karsten; Newman, John W.; Pietilainen, Kirsi H.; Pihlajamaki, Jussi; Pirinen, Eija; Klingenspor, Martin; Hanhineva, Kati; Raiko, Juho; Virtanen, Kirsi A.
Human whole-blood NAD+ levels do not vary with age or lifestyle interventions

人类全血NAD水平不随年龄或生活方式干预而变化

Nature Metabolism
IF20.8
2026-05-140
PRE
Maria M. Trętowicz; Angelique M. L. Scantlebery; Bauke V. Schomakers; Kaan D. Eroğlu; Michel van Weeghel; Vera Spek; Kasper T. Vinten; Luc Legon; Evrim Coskun; Fernando Millan-Domingo; Gloria Olaso-Gonzalez; Maria Carmen Gomez-Cabrera; Silvia Montoro-García; Clara Noguera-Navarro; André B. P. van Kuilenburg; Sofia Moco; Juliette C. van Hattum; Harald T. Jørstad; Mohammed Benali; Jantine van der Helder; Esmee J. M. Biersteker; Maheswary Muniandy; Kirsi H. Pietiläinen; Eija Pirinen; P. Eline Slagboom; Marian Beekman; Joris Deelen; Rubén Zapata-Pérez; Peter J. M. Weijs; Michael Tieland; Georges E. Janssens; Riekelt H. Houtkooper
Human Skeletal Muscle Mitochondria Responses to Weight Loss Induced by Bariatric Surgery or Lifestyle Intervention

人体骨骼肌线粒体对减肥手术或生活方式干预所诱导的体重减轻的响应

Acta Physiologica
IF5.6
2026-02-010
OAAI
Van Der Kolk, Birgitta W.; Heinonen, Sini; White, James W.; Wagner, Anita; Karppinen, Jari E.; Saari, Sina; Muniandy, Maheswary; Metsikko, Simo; Dillon, Eugene T.; Groop, Per-henrik; Saarinen, Tuure; Le Roux, Carel W.; Virtanen, Kirsi A.; Docherty, Neil G.; Pirinen, Eija; Juuti, Anne; Pietilainen, Kirsi H.
The effect of obesity and aging on NAD+/Sirtuin metabolism transcription and DNA methylation in subcutaneous adipose tissue of monozygotic twin pairs discordant for BMI

肥胖和衰老对体重指数不一致的单卵双胞胎皮下脂肪组织中NAD+/Sirtuin代谢转录和DNA甲基化的影响

International Journal of Obesity
IF3.8
2026-01-050
OAAI
Helena A. K. Lapatto; Birgitta W. van der Kolk; Maheswary Muniandy; Sini Heinonen; Aino Heikkinen; Marcus Alvarez; Seung Hyuk T. Lee; Riikka Jokinen; Jesper Lundbom; Juho Kuula; Antti Hakkarainen; Per-Henrik Groop; Jaakko Kaprio; Taru Tukiainen; Miina Ollikainen; Päivi Pajukanta; Eija Pirinen; Kirsi H. Pietiläinen
Emerging strategies, applications and challenges of targeting NAD+ in the clinic

张 J, 王H-L, Lautrup S, Nilsen HL, Treebak JT, Watne LO, 等. 靶向NAD+的临床新兴策略、应用与挑战。Nat Aging. (2025). doi: 10.1038/s43587-025-00947-6

Nature Aging
IF19.4
2025-09-090
PRE
Jianying Zhang; He-Ling Wang; Sofie Lautrup; Hilde Loge Nilsen; Jonas T. Treebak; Leiv Otto Watne; Geir Selbæk; Lindsay E. Wu; Torbjørn Omland; Eija Pirinen; Tin Cho Cheung; Jun Wang; Mathias Ziegler; Ole-Bjørn Tysnes; Rubén Zapata-Pérez; Santina Bruzzone; Carles Canto; Michela Deleidi; Georges E. Janssens; Riekelt H. Houtkooper; Morten Scheibye-Knudsen; Masaya Koshizaka; Koutaro Yokote; Eric Verdin; Vilhelm A. Bohr; Charalampos Tzoulis; David A. Sinclair; Evandro Fei Fang
Nicotinamide riboside first alleviates symptoms but later downregulates dopamine metabolism in proteasome inhibition mouse model of Parkinson's disease

在帕金森病的蛋白酶体抑制小鼠模型中，烟酰胺核苷首先缓解症状，但随后下调多巴胺代谢

HELIYON
IF3.6
2024-07-010
OAAI
Turconi, Giorgio; Alam, Farhan; Sengupta, Tanima; Pirnes-Karhu, Sini; Olfat, Soophie; Schmidt, Mark S.; Matlik, Kart; Montano-Rodriguez, Ana; Heiskanen, Vladimir; Garton, Daniel; Piepponen, Petteri T.; Brenner, Charles; Holmberg, Carina I.; Nilsen, Hilde; Pirinen, Eija; Andressoo, Jaan-Olle
Metabolic support by macrophages sustains colonic epithelial homeostasis

巨噬细胞的代谢支持维持结肠上皮稳态

CELL METABOLISM
IF30.9
2023-11-0119
OAAI
Fritsch, Stephanie Deborah; Sukhbaatar, Nyamdelger; Gonzales, Karine; Sahu, Alishan; Tran, Loan; Vogel, Andrea; Mazic, Mario; Wilson, Jayne Louise; Forisch, Stephan; Mayr, Hannah; Oberle, Raimund; Weiszmann, Jakob; Brenner, Martin; Vanhoutte, Roeland; Hofmann, Melanie; Pirnes-Karhu, Sini; Magnes, Christoph; Kueurohnast, Torben; Weckwerth, Wolfram; Bock, Christoph; Klavins, Kristaps; Hengstschlaeger, Markus; Moissl-Eichinger, Christine; Schabbauer, Gernot; Egger, Gerda; Pirinen, Eija; Verhelst, Steven H. L.; Weichhart, Thomas
Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD plus metabolism in humans
CELL REPORTS
IF6.9
2023-09-013
OA
U-Din, Mueez; de Mello, Vanessa D.; Tuomainen, Marjo; Raiko, Juho; Niemi, Tarja; Fromme, Tobias; Klavus, Anton; Gautier, Nadine; Haimilahti, Kimmo; Lehtonen, Marko; Kristiansen, Karsten; Newman, John W.; Pietilaeinen, Kirsi H.; Pihlajamaeki, Jussi; Amri, Ez-Zoubir; Klingenspor, Martin; Nuutila, Pirjo; Pirinen, Eija; Hanhineva, Kati; Virtanen, Kirsi A.
NAD+ repletion with niacin counteracts cancer cachexia

NAD充满烟酸可抵消癌症恶病质

NATURE COMMUNICATIONS
IF15.7
2023-04-0324
OAAI
Beltra, Marc; Pollanen, Noora; Fornelli, Claudia; Tonttila, Kialiina; Hsu, Myriam Y.; Zampieri, Sandra; Moletta, Lucia; Corra, Samantha; Porporato, Paolo E.; Kivelae, Riikka; Viscomi, Carlo; Sandri, Marco; Hulmi, Juha J.; Sartori, Roberta; Pirinen, Eija; Penna, Fabio
Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism
MOLECULAR AND CELLULAR BIOLOGY
IF2.7
2023-03-27119
OAAI
Pirinen, Eija; Kuulasmaa, Teemu; Pietila, Marko; Heikkinen, Sami; Tusa, Maija; Itkonen, Paula; Boman, Susanna; Skommer, Joanna; Virkamaki, Antti; Hohtola, Esa; Kettunen, Mikko; Fatrai, Szabolcs; Kansanen, Emilia; Koota, Suvi; Niiranen, Kirsi; Parkkinen, Jyrki; Levonen, Anna-Liisa; Yla-Herttuala, Seppso; Hiltunen, J. Kalervo; Alhonen, Leena; Smith, Ulf; Janne, Juhani; Laakso, Markku
Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study

烟酰胺核苷改善肌肉线粒体生物合成、卫星细胞分化和肠道微生物群的双生子研究

SCIENCE ADVANCES
IF12.5
2023-01-1348
OAAI
Lapatto, Helena A. K.; Kuusela, Minna; Heikkinen, Aino; Muniandy, Maheswary; van der Kolk, Birgitta W.; Gopalakrishnan, Swetha; Pollanen, Noora; Sandvik, Martin; Schmidt, Mark S.; Heinonen, Sini; Saari, Sina; Kuula, Juho; Hakkarainen, Antti; Tampio, Janne; Saarinen, Tuure; Taskinen, Marja-Riitta; Lundbom, Nina; Groop, Per-Henrik; Tiirola, Marja; Katajisto, Pekka; Lehtonen, Marko; Brenner, Charles; Kaprio, Jaakko; Pekkala, Satu; Ollikainen, Miina; Pietilainen, Kirsi H.; Pirinen, Eija

研究方向

暂未获取到该数据
K
Kirsi H. Pietiläinen
H 指数:77论文数:439被引数:2.7万
J
Johan Auwerx
H 指数:183论文数:915被引数:12.6万
K
Kirsi A. Virtanen
H 指数:50论文数:189被引数:1.5万
J
Jussi Pihlajamäki
H 指数:73论文数:377被引数:2.1万
M
Maheswary Muniandy
H 指数:14论文数:33被引数:1,298
S
Sini Heinonen
H 指数:28论文数:77被引数:2,999
N
Nina Lundbom
H 指数:54论文数:194被引数:9,723
A
Antti Hakkarainen
H 指数:51论文数:248被引数:8,517
L
Leena Alhonen
H 指数:44论文数:277被引数:7,039
M
Marko Pietilä
H 指数:23论文数:50被引数:1,462