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A

Ana J. García‐Sáez

Institute of Genetics

50H指数
208论文数
1.6W被引数
收录论文 112
发表时间
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Disruption of MCL1/BOK transmembrane interaction as a novel strategy to induce cell death in tumours破坏MCL1/BOK跨膜相互作用作为诱导肿瘤细胞死亡的新策略
errCell Death & Disease
IF9.6
err2026-07-03
err0
errOAAI
errM. Buffa; D. Leiva; A. Garcia-Jareño; M. Garcés-Flores; E. Díaz; F. Lucantoni; M. Telechea; L. Chen; E. Lucendo; R. Shalaby; F. Lolicato; W. Kulig; AJ. Garcia-Saez; G. Moreno-Bueno; M. Sancho; M. Orzáez
err分享
err收藏
Author Correction: 7-Dehydrocholesterol is an endogenous suppressor of ferroptosis作者更正: 7-脱氢胆固醇是铁死亡的内源性抑制因子
errNature
IF48.5
err2026-03-24
err0
PREAI
errFlorencio Porto Freitas; Hamed Alborzinia; Ancély Ferreira dos Santos; Palina Nepachalovich; Lohans Pedrera; Omkar Zilka; Alex Inague; Corinna Klein; Nesrine Aroua; Kamini Kaushal; Bettina Kast; Svenja M. Lorenz; Viktoria Kunz; Helene Nehring; Thamara N. Xavier da Silva; Zhiyi Chen; Sena Atici; Sebastian G. Doll; Emily L. Schaefer; Ifedapo Ekpo; Werner Schmitz; Aline Horling; Peter Imming; Sayuri Miyamoto; Ann M. Wehman; Thiago C. Genaro-Mattos; Karoly Mirnics; Lokender Kumar; Judith Klein-Seetharaman; Svenja Meierjohann; Isabel Weigand; Matthias Kroiss; Georg W. Bornkamm; Fernando Gomes; Luis Eduardo Soares Netto; Manjima B. Sathian; David B. Konrad; Douglas F. Covey; Bernhard Michalke; Kurt Bommert; Ralf C. Bargou; Ana Garcia-Saez; Derek A. Pratt; Maria Fedorova; Andreas Trumpp; Marcus Conrad; José Pedro Friedmann Angeli
err分享
err收藏
What does BCL-2 do? From new molecular insights to the clinical implicationsBCL-2的功能是什么？从新的分子见解到临床意义
errcell death & differentiation
IF0
err2026-02-19
err0
PREAI
errCarlo M. Croce; Stephen W. G. Tait; Ana J. Garcia-Sáez; Andreas Villunger; Anthony Letai; Harriet S. Walter; Martin J. S. Dyer; Douglas R. Green; Yufang Shi; Gerry Melino
err分享
err收藏
Mitochondrial dynamics and pore formation in regulated cell death pathways线粒体动力学和孔道形成在调控性细胞死亡通路中的作用
errTrends in Biochemical Sciences
IF11
err2025-10-02
err0
errOAAI
errLisa Hohorst; Uris Ros; Ana J. Garcia-Saez
err分享
err收藏
Dynamic regulation of cell death signaling细胞死亡信号通路的动态调控
errCurrent Opinion in Cell Biology
IF4.3
err2025-09-26
err0
PREAI
errAsma Majoul; Ana J. Garcia-Saez
err分享
err收藏
Activator of apoptosis harakiri (HRK) localisation at mitochondria alters mitochondrial morphology independently of other BCL-2 proteins促凋亡因子 harakiri (HRK) 在线粒体的定位独立于其他 BCL-2 蛋白，改变了线粒体的形态。
errThe FEBS Journal
IF0
err2025-09-12
err0
errOAAI
errLouise E. King; Lukas Faber; Ana J. García-Sáez
err分享
err收藏
Convolutional Neural Network approach to classify mitochondrial morphologies卷积神经网络方法用于分类线粒体形态学
errcomputational chemistry
IF3.1
err2025-06-02
err0
PREAI
errZaghbani, Soumaya; Faber, Lukas; Garcia-Saez, Ana J.
err分享
err收藏
MLKL activity requires a splicing-regulated, druggable intramolecular interactionMLKL的活性需要一种受剪接调控的、可成药的分子内相互作用。
errMOLECULAR CELL
IF16.6
err2025-04-01
err0
errOAAI
errRos, Uris; Martinez-Osorio, Veronica; Valiente, Pedro A.; Abdelwahab, Yasmin; Gojkovic, Milos; Shalaby, Raed; Zanna, Silvia; Saggau, Julia; Wachsmuth, Laurens; Nemade, Harshal N.; Zoeller, Jonathan; Lottermoser, Hannah; Chen, Yu-Guang; Ibrahim, Mohamed; Kelepouras, Konstantinos; Vasilikos, Lazaros; Bedoya, Paula; Espiritu, Rafael A.; Mueller, Stefan; Altmannova, Veronika; Tieleman, D. Peter; Weir, John; Langer, Julian; Adam, Matti; Walczak, Henning; Wong, W. Wei-Lynn; Liccardi, Gianmaria; Mollenhauer, Martin; Pasparakis, Manolis; Peltzer, Nieves; Garcia-Saez, Ana J.
err分享
err收藏
MitoSkel: AI tool for semantic segmentation and quantification of mitochondria from light microscopy imagesMitoSkel: 用于从光学显微镜图像中语义分割和量化线粒体的AI工具
errBIOMEDICAL SIGNAL PROCESSING AND CONTROL
IF4.9
err2025-02-28
err0
errOAAI
errZaghbani, Soumaya; Pranti, Rubaiya Kabir; Faber, Lukas; Garcia-Saez, Ana J.
err分享
err收藏
A novel biosensor for the spatiotemporal analysis of STING activation during innate immune responses to dsDNA一种用于分析dsDNA诱导固有免疫应答期间STING激活时空特征的新型生物传感器
errEMBO JOURNAL
IF8.3
err2025-02-21
err0
errOAAI
errSmarduch, Steve; Moreno-Velasquez, Sergio David; Ilic, Doroteja; Dadsena, Shashank; Morant, Ryan; Ciprinidis, Anja; Pereira, Gislene; Binder, Marco; Garcia-Saez, Ana J.; Acebron, Sergio P.
err分享
err收藏
Ferroptosis triggers mitochondrial fragmentation via Drp1 activation
errCELL DEATH & DISEASE
IF9.6
err2025-01-25
err0
errOAAI
errPedrera, Lohans; Clemente, Laura Prieto; Dahlhaus, Alina; Nasudivar, Sara Lotfipour; Tishina, Sofya; Gonzalez, Daniel Olmo; Stroh, Jenny; Yapici, Fatma Isil; Singh, Randhwaj Pratap; Grotehans, Nils; Langer, Thomas; Garcia-Saez, Ana J.; von Karstedt, Silvia
err分享
err收藏
Iron-Induced Lipid Oxidation Alters Membrane Mechanics Favoring Permeabilization
errLANGMUIR
IF3.9
err2024-11-12
err1
errOAAI
errNasudivar, Sara Lotfipour; Pedrera, Lohans; Garcia-Saez, Ana J.
err分享
err收藏
Targeting mitochondrial metabolism by the mitotoxin bromoxib in leukemia and lymphoma cells
errCELL COMMUNICATION AND SIGNALING
IF8.9
err2024-11-12
err1
errOAAI
errSchmitt, Laura; Krings, Karina S.; Wolsing, Andre; Buque, Xabier; Zimmermann, Marcel; Flores-Romero, Hector; Lenz, Thomas; Lechtenberg, Ilka; Peter, Christoph; Stork, Bjoern; Teusch, Nicole; Proksch, Peter; Stuehler, Kai; Garcia-Saez, Ana J.; Reichert, Andreas S.; Aspichueta, Patricia; Bhatia, Sanil; Wesselborg, Sebastian
err分享
err收藏
Lipid unsaturation promotes BAX and BAK pore activity during apoptosis脂质不饱和度在细胞凋亡过程中促进BAX和BAK孔活性
errNATURE COMMUNICATIONS
IF15.7
err2024-06-03
err4
errOAAI
errDadsena, Shashank; Arenas, Rodrigo Cuevas; Vieira, Goncalo; Brodesser, Susanne; Melo, Manuel N.; Garcia-Saez, Ana J.
err分享
err收藏
Nanobodies as novel tools to monitor the mitochondrial fission factor Drp1
errLIFE SCIENCE ALLIANCE
IF2.9
err2024-05-30
err0
errOAAI
errFroehlich, Theresa; Jenner, Andreas; Cavarischia-Rega, Claudia; Fagbadebo, Funmilayo; Lurz, Yannic; Frecot, Desiree, I; Kaiser, Philipp; Nueske, Stefan; Scholz, Armin M.; Schaeffer, Erik; Garcia-Saez, Ana J.; Macek, Boris; Rothbauer, Ulrich
err分享
err收藏
Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2
errCELL DEATH DISCOVERY
IF7
err2024-03-09
err6
errOAAI
errSchmitt, Laura; Lechtenberg, Ilka; Driessen, Daniel; Flores-Romero, Hector; Skowron, Margaretha A.; Sekeres, Marlena; Hoppe, Julia; Krings, Karina S.; Llewellyn, Tanya R.; Peter, Christoph; Stork, Bjorn; Qin, Nan; Bhatia, Sanil; Nettersheim, Daniel; Fritz, Gerhard; Garcia-Saez, Ana J.; Mueller, Thomas J. J.; Wesselborg, Sebastian
err分享
err收藏
A guideline on the molecular ecosystem regulating ferroptosis调控铁死亡的分子生态系统指南
errNATURE CELL BIOLOGY
IF19.1
err2024-02-29
err53
PREAI
errDai, Enyong; Chen, Xin; Linkermann, Andreas; Jiang, Xuejun; Kang, Rui; Kagan, Valerian E.; Bayir, Huelya; Yang, Wan Seok; Garcia-Saez, Ana J.; Ioannou, Maria S.; Janowitz, Tobias; Ran, Qitao; Gu, Wei; Gan, Boyi; Krysko, Dmitri V.; Zhu, Xiaofeng; Wang, Jiayi; Krautwald, Stefan; Toyokuni, Shinya; Xie, Yangchun; Greten, Florian R.; Yi, Qing; Schick, Joel; Liu, Jiao; Gabrilovich, Dmitry I.; Liu, Jinbao; Zeh, Herbert J.; Zhang, Donna D.; Yang, Minghua; Iovanna, Juan; Kopf, Manfred; Adolph, Timon E.; Chi, Jen-Tsan; Li, Changfeng; Ichijo, Hidenori; Karin, Michael; Sankaran, Vijay G.; Zou, Weiping; Galluzzi, Lorenzo; Bush, Ashley I.; Li, Binghui; Melino, Gerry; Baehrecke, Eric H.; Lotze, Michael T.; Klionsky, Daniel J.; Stockwell, Brent R.; Kroemer, Guido; Tang, Daolin
err分享
err收藏
Expanding roles of BCL-2 proteins in apoptosis execution and beyond
errJOURNAL OF CELL SCIENCE
IF3.6
err2023-11-23
err14
errOAAI
errKing, Louise E.; Hohorst, Lisa; Garcia-Saez, Ana J.
err分享
err收藏
Calcium as a master regulator of ferroptosis and other types of regulated necrosis
errCELL CALCIUM
IF4
err2023-09-01
err16
PREAI
errPedrera, Lohans; Ros, Uris; Garcia-Saez, Ana J.
err分享
err收藏
Dying in self-defense: cell death signaling in animals and plants
errCELL DEATH AND DIFFERENTIATION
IF15.4
err2023-08-10
err1
errOAAI
errGarcia-Saez, Ana J.
err分享
err收藏

研究方向

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合作学者
合作期刊
G
Guido Kroemer
H 指数: 283 · 论文数: 2.3K
M
Michael Karin
H 指数: 254 · 论文数: 904
C
Carlo M. Croce
H 指数: 209 · 论文数: 1.8K
D
Douglas R. Green
H 指数: 199 · 论文数: 966
J
Josef Penninger
H 指数: 174 · 论文数: 1.6K
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